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The map label for this gene is lysN [H]

Identifier: 126447000

GI number: 126447000

Start: 1572561

End: 1573676

Strand: Reverse

Name: lysN [H]

Synonym: BMA10247_A1632

Alternate gene names: 126447000

Gene position: 1573676-1572561 (Counterclockwise)

Preceding gene: 126446634

Following gene: 262192867

Centisome position: 66.89

GC content: 74.1

Gene sequence:

>1116_bases
ATGACGCTCGCCGCCGCCGTCGATTATCCGTTCGCCGCGCCGTTCGCCGATCCGCAGGGCTCGCCGATCCGCGAGCTGTT
CAAGCACGTCGGCAAGCCGGGGATGATCTCGTTCGCGGGCGGCTATCCGTCCGCCGAGCTGTTCGACCGCGAGGGCATCG
CGGCGGCGTTCGCCGACGCGGCCCGCGACGATCCGGTGGCCTGCCTGCAATATGGCGACACCGCCGGCCAGCCCGGCCTG
CGCGCCGCGCTCGCCGACTGGATGACGCGCGCGCGCGGCGTCGCGTGCGACGCTTCGCAGGTGCTCGTCACGACGGGCTC
GCAGCAAGGCTTCGATCTGCTCGTGCGCGCGCTGATCGAGCCGGGCGACGTCGCGCTCGTCGAGGCGCCCGCGTATCCGG
CCGCGCTGCAGGCGCTGCGGCTCGCGGGCGCGAAGCTCGTGCCGGTGCGCACCGATGCCGACGGCGTCGACCCCGACGCG
CTCGCCGCGCAGCTTGCCGCGTGGCCCGCGGCCGAGCGCCGTCCGAAGCTGCTGTATACGGTGCCGACGTTCGCGAATCC
GACCGGCGCGACGCTGCCGCCGGCGCGCCGCGCGCGGCTCGCGGCGGTCGCGGCCGACGCGCGGCTCGTGCTCGTCGAGG
ACGATCCGTACGCGGACCTGCGTTTCGCCGGCGAGCCCGTGAAGCCCGTGCTCGCGCATGACGGCGCATCGGACTGGACC
GTCTATCTCGGCAGCCTGTCGAAAATCGTCGCGCCGGGCCTGCGGATCGGCTGGGCGGTCGCGCCCGCCGCGGTTCTGCG
CCGGATGACCGTGGCGAAGCAGACGAGCGATTTGTGCACCGCGCCGATCGCGCAGGAAGCGATCCGCCGCTACCTGGCGA
GCGGCCGGCTTGCCGCGCATTTGCGCACGATCGCGCAGACTTACGGCAGCCGTTGCCGCGCGCTCGTGAGCGCGCTCGAG
CACAACGTGATGTACGTGCCGGGCGCGGCGTTCTACGCGCGCGACGCGGATGCGGGCAGCCTGCGGCTGTCGTTCGCCGC
GCCGGGCGAAGCGGAGATTTTCGAGGGCGTGCGCCGGCTGCGCGCGGCGCTCGCGGCGTGCCGCCAGCGCACGTGA

Upstream 100 bases:

>100_bases
CGCGGGCAATGCGACCGGCATCTTCAAGATGACGGCCGCGGCCTGATTCGCAGCGTCCCCGATTCGCCTGTTGCCCGACT
TCCATCGCACCGGAGCCGCC

Downstream 100 bases:

>100_bases
CGCACGTGCGGCGGGAGCGCCGCGCGCCGGGCACGCGAGCCCGCCGATAGGCCGAATGGCCGGTGCGCTTGCATGCGGCG
CGCGAACGCGGTCCAATCGA

Product: aminotransferase family protein

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADAARDDPVACLQYGDTAGQPGL
RAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIEPGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDA
LAAQLAAWPAAERRPKLLYTVPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAHLRTIAQTYGSRCRALVSALE
HNVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAALAACRQRT

Sequences:

>Translated_371_residues
MTLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADAARDDPVACLQYGDTAGQPGL
RAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIEPGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDA
LAAQLAAWPAAERRPKLLYTVPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAHLRTIAQTYGSRCRALVSALE
HNVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAALAACRQRT
>Mature_370_residues
TLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADAARDDPVACLQYGDTAGQPGLR
AALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIEPGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDAL
AAQLAAWPAAERRPKLLYTVPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWTV
YLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAHLRTIAQTYGSRCRALVSALEH
NVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAALAACRQRT

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=324, Percent_Identity=30.2469135802469, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI33469970, Length=324, Percent_Identity=30.2469135802469, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1787710, Length=333, Percent_Identity=28.8288288288288, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790797, Length=301, Percent_Identity=28.2392026578073, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788722, Length=271, Percent_Identity=28.4132841328413, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321236, Length=326, Percent_Identity=27.6073619631902, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321929, Length=295, Percent_Identity=24.0677966101695, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356535, Length=264, Percent_Identity=23.8636363636364, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 39083; Mature: 38952

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADA
CCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCHHHHHHHH
ARDDPVACLQYGDTAGQPGLRAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIE
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCC
PGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDALAAQLAAWPAAERRPKLLYT
CCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEE
VPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
CCCCCCCCCCCCCCHHHHHHHEEECCCEEEEECCCCCCCEEECCCCCCHHHHCCCCCCHH
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
LRTIAQTYGSRCRALVSALEHNVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRL
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHH
RAALAACRQRT
HHHHHHHHCCC
>Mature Secondary Structure 
TLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADA
CEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCHHHHHHHH
ARDDPVACLQYGDTAGQPGLRAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIE
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCC
PGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDALAAQLAAWPAAERRPKLLYT
CCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEE
VPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
CCCCCCCCCCCCCCHHHHHHHEEECCCEEEEECCCCCCCEEECCCCCCHHHHCCCCCCHH
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
LRTIAQTYGSRCRALVSALEHNVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRL
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHH
RAALAACRQRT
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA