BacMap

Definition	Burkholderia mallei NCTC 10247 chromosome II, complete genome.
Accession	NC_009079
Length	2,352,693

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 126446991

GI number: 126446991

Start: 1720530

End: 1721306

Strand: Reverse

Name: fabG [H]

Synonym: BMA10247_A1782

Alternate gene names: 126446991

Gene position: 1721306-1720530 (Counterclockwise)

Preceding gene: 126446793

Following gene: 262192857

Centisome position: 73.16

GC content: 67.95

Gene sequence:

>777_bases
GTGAACCTGAACCTCAACGACAAGGTGGTGATCGTGACGGGCGGCGGCTCGGGCATCGGCGGCGCGATCACGCTCGCGCT
GGCCGAAGAAGGGGCGATTCCGGTCGTGTTCGGCCGCAGCCCGCTCGCCGACGCGTTCGCCGAACGCCTGCGCGCATTGC
AGTCGCGCGCGCGTTTCGTGCGCGTCGATCTCGTCGACGACGCGCGCTGCCGCGAGGCTGTCGACGAAACGGTCGCGGCG
TTCGGCCGGATCGACGGGCTCGTCAACAACGCGGGCATCAACGACGGCGTCGGACTCGACGCGGGACGCGACGCATTCGT
CGCGTCGCTCGAAAGCAATCTGATCCATTACTACGTGATCGCGCACTACTGCCTGCCGCATCTGAAGGCGAGCCGCGGCG
CGATCGTCAACGTATCGTCGAAGACCGCGATCACCGGGCAGGGCGGCACGAGCGGCTATTGCGCCTCGAAGGGCGCGCAG
CTCTCGCTGACGCGGGAATGGGCGGCATCGCTCGCCGACGACGGCGTGCGCGTGAACGCGGTGATTCCCGCCGAGGTGAT
GACGCCGCTCTACGCGAACTGGCTCGCGCGGTTCGACGATCCGGACGCGAAGCTGCAGTCGATCACGCGCAAGATCCCGC
TCGGCAAGCGGATGACGAGCGCCGAGGAGATCGCATGGACGACGGTGTTCCTGCTGTCCGAGCGCGCGTCGCACACGACG
GGGCAGTGGCTGTTCGTCGACGGCGGCTATACGCATCTCGATCGCGCGCTGACCTGA

Upstream 100 bases:

>100_bases
GCATGGACGCCCGGGCCGCGGTCGCGGCCCGGCGATGCGCGCGGCACGCGCCGGCGCTTGCTTCGGCGCGTGCCGTTCGT
CGAAACATCGGAGCAGACAA

Downstream 100 bases:

>100_bases
CGCGGCTTCACGCACGACGAACCACGGAGCGCACGGTGCGATACTGCCTGGCCTTGGACCTGAAGGACGACCCGGATGCG
ATCGCGCGCTACGAAGCGCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNLNLNDKVVIVTGGGSGIGGAITLALAEEGAIPVVFGRSPLADAFAERLRALQSRARFVRVDLVDDARCREAVDETVAA
FGRIDGLVNNAGINDGVGLDAGRDAFVASLESNLIHYYVIAHYCLPHLKASRGAIVNVSSKTAITGQGGTSGYCASKGAQ
LSLTREWAASLADDGVRVNAVIPAEVMTPLYANWLARFDDPDAKLQSITRKIPLGKRMTSAEEIAWTTVFLLSERASHTT
GQWLFVDGGYTHLDRALT

Sequences:

>Translated_258_residues
MNLNLNDKVVIVTGGGSGIGGAITLALAEEGAIPVVFGRSPLADAFAERLRALQSRARFVRVDLVDDARCREAVDETVAA
FGRIDGLVNNAGINDGVGLDAGRDAFVASLESNLIHYYVIAHYCLPHLKASRGAIVNVSSKTAITGQGGTSGYCASKGAQ
LSLTREWAASLADDGVRVNAVIPAEVMTPLYANWLARFDDPDAKLQSITRKIPLGKRMTSAEEIAWTTVFLLSERASHTT
GQWLFVDGGYTHLDRALT
>Mature_258_residues
MNLNLNDKVVIVTGGGSGIGGAITLALAEEGAIPVVFGRSPLADAFAERLRALQSRARFVRVDLVDDARCREAVDETVAA
FGRIDGLVNNAGINDGVGLDAGRDAFVASLESNLIHYYVIAHYCLPHLKASRGAIVNVSSKTAITGQGGTSGYCASKGAQ
LSLTREWAASLADDGVRVNAVIPAEVMTPLYANWLARFDDPDAKLQSITRKIPLGKRMTSAEEIAWTTVFLLSERASHTT
GQWLFVDGGYTHLDRALT

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=204, Percent_Identity=35.2941176470588, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=35.6862745098039, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=32.2448979591837, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=30.1587301587302, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=31.203007518797, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=31.8725099601594, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=29.8850574712644, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=29.718875502008, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI31542939, Length=237, Percent_Identity=27.8481012658228, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=31.1023622047244, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=30.8457711442786, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=30.8080808080808, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=32.2834645669291, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=29.718875502008, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=32.156862745098, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=32, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=28.8, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=32.4324324324324, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=28.1746031746032, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=29.8449612403101, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=29.296875, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=27.4900398406374, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=26.0700389105058, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=34.6303501945525, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=33.5907335907336, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=35.7723577235772, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=34.9624060150376, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=35.5212355212355, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=31.2741312741313, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=33.0827067669173, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=273, Percent_Identity=34.0659340659341, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=34.0996168582375, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=32.824427480916, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=275, Percent_Identity=31.2727272727273, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=30.3030303030303, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=31.0077519379845, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=32.9457364341085, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=34.2307692307692, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=31.7269076305221, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=274, Percent_Identity=32.1167883211679, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=31.4814814814815, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=32.5842696629214, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=32.4, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=33.7121212121212, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=31.6981132075472, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=29.0441176470588, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=30.4511278195489, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=223, Percent_Identity=25.5605381165919, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=27.34375, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=29.9212598425197, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=39.6825396825397, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=34.136546184739, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=34.9397590361446, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=34.4, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=33.9920948616601, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=32.1428571428571, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=31.3492063492063, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357673, Length=258, Percent_Identity=26.3565891472868, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27487; Mature: 27487

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNLNDKVVIVTGGGSGIGGAITLALAEEGAIPVVFGRSPLADAFAERLRALQSRARFV
CCCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCEE
RVDLVDDARCREAVDETVAAFGRIDGLVNNAGINDGVGLDAGRDAFVASLESNLIHYYVI
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHH
AHYCLPHLKASRGAIVNVSSKTAITGQGGTSGYCASKGAQLSLTREWAASLADDGVRVNA
HHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHCCCCEEEEE
VIPAEVMTPLYANWLARFDDPDAKLQSITRKIPLGKRMTSAEEIAWTTVFLLSERASHTT
EECHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEHHHCCCCCC
GQWLFVDGGYTHLDRALT
CCEEEEECCHHHHHHHCC
>Mature Secondary Structure
MNLNLNDKVVIVTGGGSGIGGAITLALAEEGAIPVVFGRSPLADAFAERLRALQSRARFV
CCCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCEE
RVDLVDDARCREAVDETVAAFGRIDGLVNNAGINDGVGLDAGRDAFVASLESNLIHYYVI
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHH
AHYCLPHLKASRGAIVNVSSKTAITGQGGTSGYCASKGAQLSLTREWAASLADDGVRVNA
HHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHCCCCEEEEE
VIPAEVMTPLYANWLARFDDPDAKLQSITRKIPLGKRMTSAEEIAWTTVFLLSERASHTT
EECHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEHHHCCCCCC
GQWLFVDGGYTHLDRALT
CCEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]