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The map label for this gene is ndh [H]

Identifier: 126446909

GI number: 126446909

Start: 310116

End: 311498

Strand: Direct

Name: ndh [H]

Synonym: BMA10247_A0354

Alternate gene names: 126446909

Gene position: 310116-311498 (Clockwise)

Preceding gene: 126446346

Following gene: 126446414

Centisome position: 13.18

GC content: 69.27

Gene sequence:

>1383_bases
ATGCATCGTTTCATCATCGTCGGCGGCGGTGCGGGCGGACTCGAACTGGCGACCCGCCTCGGGGATCGCTATGGCGCGCG
CGGCGATCGTCCCGCGCGCGCGCTCGTGACGCTCGTCGACCGTTACCCGACCCATATCTGGAAGCCCCTGCTGCACGAAG
TGGCGGCGGGCAGCATGGATCCGTTCACGCAGGAGCTCGAATACGCGGCGCAGGCGCGCTGGCACGGCTTCGAATTTCAC
CAGGGCGAACTGATCGCGCTCGATCGCGCGTCGCGGCGCGTGACGCTCGCGCCCGTTGCCGATAACGACGGCGCCGAGTT
GCTGCCGCTGCGCGAGCTCGAATACGACACGCTCGTCATCGCGATCGGCAGCACGACGCATTATTTCGGCGTGCAGGGCG
CGCAGCAGCACTCGATCGCACTCGACACGGTCGCCGAGGCGGAGCGGTTCCGCAAGCGCCTGATCGCCGCGTGCATGCGC
GCCGAGCATCAGCCCGCGGAGCCGGCCGTGCGGACCGCCGAGGGCGGGCCCGAGCAGGCCGTGGAGCCGACGGACGCGGC
GCAGGTGTCGGCCTCGCCGCGCATTCAGGTTGCGATCGTCGGCGGCGGCGCGACGGGCGTGGAACTGTCCGCCGAGTTGC
GCAATACCGCGCAGGTGCTGTCCGCGTACGGGTTGCACAAGCTCGATCCGCGGCACGACGTCGGCATCGTGCTGATCGAA
TCGGGGCCGCGCATTCTGCCGGCGCTGCAGGAGCGCGTGTCGACGGCGACCGCCGAGCTGCTCGAGAAGCTCGGCGTGCG
CCTGCTGCTCGGCGAGCGCGTGACGGAGGTCGCGCCGGGCGTCGTGCGCACCGCGAGTGGCAAGAGCGTGCGGGCGGATC
TGACCGTGTGGGCGGCGGGCATCAAGGCGCCTTCGGTGCTCGCGAAGCTCGACGGCCTCGAAGTGAACAAGCTCGGCCAA
CTGGCCGTGCGCCGCACGCTGCAGACCGAAACCGATCCGGATGTATTCGCGTTCGGCGATTGCGCCGGCTGCGAGTGGCC
GGGCCACGAGCGTAACGTGCCGCCGCGCGCGCAAGCCGCGCATCAGCAGGCGAGCTTCATGCTGCGCGCGCTCGCAAACC
GGCTCGAAGGCCGGCCGCTGCCCGAATTCACCTATCGCGATTTCGGCTCGCTGGTGTCGCTCGGGCACTTCAGTGCGGTC
GGCAATCTGATGGGCGGGCTGATCGGCGGCAACATGCTGATCGAAGGGCTGTTCGCGCGCTTCATGTATATGTCGCTGTA
TCGGCTGCACATCGCGGCGCTGCACGGCTATCCGCGGATGGTGCTCGATACGGTCGCGCACTGGTTGAGGCGCTCGACGC
TGCCGCGTGTGAAGCTGCATTAG

Upstream 100 bases:

>100_bases
TGCCCAAAGTGTCCGAACTAGTTAGGATGTCGATTGGCGACGAACGCGGACGCGCTCGCCGCCGTGACCGCAGGCAGTCT
CGAATCGTAAGGGGAATCGG

Downstream 100 bases:

>100_bases
CGTGGGTGTCGACGTCCGACGTCCGACGTCCGACGCCCGACGCCCGACGCCCGACGCCCGACGCCCGACGCCCGACGCCC
GACGCCCGACGCCCAACGCC

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MHRFIIVGGGAGGLELATRLGDRYGARGDRPARALVTLVDRYPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFH
QGELIALDRASRRVTLAPVADNDGAELLPLRELEYDTLVIAIGSTTHYFGVQGAQQHSIALDTVAEAERFRKRLIAACMR
AEHQPAEPAVRTAEGGPEQAVEPTDAAQVSASPRIQVAIVGGGATGVELSAELRNTAQVLSAYGLHKLDPRHDVGIVLIE
SGPRILPALQERVSTATAELLEKLGVRLLLGERVTEVAPGVVRTASGKSVRADLTVWAAGIKAPSVLAKLDGLEVNKLGQ
LAVRRTLQTETDPDVFAFGDCAGCEWPGHERNVPPRAQAAHQQASFMLRALANRLEGRPLPEFTYRDFGSLVSLGHFSAV
GNLMGGLIGGNMLIEGLFARFMYMSLYRLHIAALHGYPRMVLDTVAHWLRRSTLPRVKLH

Sequences:

>Translated_460_residues
MHRFIIVGGGAGGLELATRLGDRYGARGDRPARALVTLVDRYPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFH
QGELIALDRASRRVTLAPVADNDGAELLPLRELEYDTLVIAIGSTTHYFGVQGAQQHSIALDTVAEAERFRKRLIAACMR
AEHQPAEPAVRTAEGGPEQAVEPTDAAQVSASPRIQVAIVGGGATGVELSAELRNTAQVLSAYGLHKLDPRHDVGIVLIE
SGPRILPALQERVSTATAELLEKLGVRLLLGERVTEVAPGVVRTASGKSVRADLTVWAAGIKAPSVLAKLDGLEVNKLGQ
LAVRRTLQTETDPDVFAFGDCAGCEWPGHERNVPPRAQAAHQQASFMLRALANRLEGRPLPEFTYRDFGSLVSLGHFSAV
GNLMGGLIGGNMLIEGLFARFMYMSLYRLHIAALHGYPRMVLDTVAHWLRRSTLPRVKLH
>Mature_460_residues
MHRFIIVGGGAGGLELATRLGDRYGARGDRPARALVTLVDRYPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFH
QGELIALDRASRRVTLAPVADNDGAELLPLRELEYDTLVIAIGSTTHYFGVQGAQQHSIALDTVAEAERFRKRLIAACMR
AEHQPAEPAVRTAEGGPEQAVEPTDAAQVSASPRIQVAIVGGGATGVELSAELRNTAQVLSAYGLHKLDPRHDVGIVLIE
SGPRILPALQERVSTATAELLEKLGVRLLLGERVTEVAPGVVRTASGKSVRADLTVWAAGIKAPSVLAKLDGLEVNKLGQ
LAVRRTLQTETDPDVFAFGDCAGCEWPGHERNVPPRAQAAHQQASFMLRALANRLEGRPLPEFTYRDFGSLVSLGHFSAV
GNLMGGLIGGNMLIEGLFARFMYMSLYRLHIAALHGYPRMVLDTVAHWLRRSTLPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=460, Percent_Identity=45.4347826086956, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6320118, Length=461, Percent_Identity=21.9088937093275, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323794, Length=380, Percent_Identity=24.2105263157895, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323515, Length=471, Percent_Identity=22.0806794055202, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 49976; Mature: 49976

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRFIIVGGGAGGLELATRLGDRYGARGDRPARALVTLVDRYPTHIWKPLLHEVAAGSMD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PFTQELEYAAQARWHGFEFHQGELIALDRASRRVTLAPVADNDGAELLPLRELEYDTLVI
HHHHHHHHHHHHHCCCCEECCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHCCCCEEEE
AIGSTTHYFGVQGAQQHSIALDTVAEAERFRKRLIAACMRAEHQPAEPAVRTAEGGPEQA
EECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
VEPTDAAQVSASPRIQVAIVGGGATGVELSAELRNTAQVLSAYGLHKLDPRHDVGIVLIE
CCCCCCHHCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
SGPRILPALQERVSTATAELLEKLGVRLLLGERVTEVAPGVVRTASGKSVRADLTVWAAG
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEECCCCCEEEEHEEEECC
IKAPSVLAKLDGLEVNKLGQLAVRRTLQTETDPDVFAFGDCAGCEWPGHERNVPPRAQAA
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHH
HQQASFMLRALANRLEGRPLPEFTYRDFGSLVSLGHFSAVGNLMGGLIGGNMLIEGLFAR
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMYMSLYRLHIAALHGYPRMVLDTVAHWLRRSTLPRVKLH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure
MHRFIIVGGGAGGLELATRLGDRYGARGDRPARALVTLVDRYPTHIWKPLLHEVAAGSMD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PFTQELEYAAQARWHGFEFHQGELIALDRASRRVTLAPVADNDGAELLPLRELEYDTLVI
HHHHHHHHHHHHHCCCCEECCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHCCCCEEEE
AIGSTTHYFGVQGAQQHSIALDTVAEAERFRKRLIAACMRAEHQPAEPAVRTAEGGPEQA
EECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
VEPTDAAQVSASPRIQVAIVGGGATGVELSAELRNTAQVLSAYGLHKLDPRHDVGIVLIE
CCCCCCHHCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
SGPRILPALQERVSTATAELLEKLGVRLLLGERVTEVAPGVVRTASGKSVRADLTVWAAG
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEECCCCCEEEEHEEEECC
IKAPSVLAKLDGLEVNKLGQLAVRRTLQTETDPDVFAFGDCAGCEWPGHERNVPPRAQAA
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHH
HQQASFMLRALANRLEGRPLPEFTYRDFGSLVSLGHFSAVGNLMGGLIGGNMLIEGLFAR
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMYMSLYRLHIAALHGYPRMVLDTVAHWLRRSTLPRVKLH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]