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The map label for this gene is dtpA [H]

Identifier: 126446855

GI number: 126446855

Start: 337554

End: 339056

Strand: Reverse

Name: dtpA [H]

Synonym: BMA10247_A0382

Alternate gene names: 126446855

Gene position: 339056-337554 (Counterclockwise)

Preceding gene: 126447475

Following gene: 126446325

Centisome position: 14.41

GC content: 66.2

Gene sequence:

>1503_bases
ATGAATACTCGCGTCTCCCAGACCCGCTCGTTCACGACGGTCTTCCTGATCGAAATGTGGGAGCGTTTCGGCTACTACGG
GATGGCGGCCCTGCTCGTCCTGTTCATGGTCGACAAGCTCCGCTTCACCGACGGTCAGGCGAACCTGACCTGGGGCGCGT
TCACCGCGCTCGTCTACGCGTCGCCGTCGATCGGCGGCTGGATCGGCGACAAGGTGCTGGGCGCGCGGCGCTCGATGATC
ATCGGCGCCGTCGTGCTGTGCGCGGGCTATCTGATGCTCGCGATTCCGAACGATCAGCTCGCGTTCATGTACACGTCGCT
CGGCGTGATCGTCGTCGGCAACGGGCTGTTCAAGTCGAACGCCGCGAACCTCGTGCGCCGCATCTACGAAGGCGACAACG
CACGCATCGATAGCGCGTTCACGATCTACTACATGGCGGTCAACATCGGCTCCACCGCGTCGATGCTCGCGACGCCGTGG
ATCAAGGATCACTGGGGCTGGCACACGGCGTTCGCCGTCTGCTGCGCGGGGATGGCGCTCGGCATTCTCAACTTCGTGCT
GATGCATCGCACGCTCGCGCACATCGGCTCGCAGCCCGACGCGCAGCCCGTTCACTGGCGCCGCCTCGCCGCGGTCGCGG
CGGGCGGCGTCGCGCTCGGCCTCGCGACGATGTACGTGCTCGGGCACAAGCAGCTCGCGGTCGCGAGCGTGTGGGTGGCC
GCGTTCGCGATTCTCGCGATCTTCGCGTACATGATCGCGAAATCGAACCGCGCCGAGCGCTCGGGCCTCATCGCCGCGCT
GCTCCTGATCGCTCAGGTGATCCTGTTCTTCATCTTCTACGTGCAGATGCAGACGTCGCTCACGCTGTTCGCGCTGCGCA
ACGTCGATCCGCGCTTCATGCTGTTCGGCACGACGCTCTTCACGTGGAGCCCCGCTCAGTTCCAGGCGCTCAATCCGATC
TGGATCATGCTGTTGAGCCCGGTGCTCGTCGCGATCTACAACGGCCTCGGCAAGCGCGGCCGCGATCTGCCCGTGGCCGG
CAAGTACGCGCTCGGCTTCGGCGTCGTCGCGCTCGGCTATCTCGCGTTCTCGATCAGCGGACGCTTCGCGGTGGACGGCC
GCGTGTCGTCGTGGTTCATGGTCGCGGGCTACGGCTTCTATTCGCTCGGCGAGCTGCTCGTGAGCGGTCTCGGCCTCGCG
ATGATCGCGCGCTACGTGCCGGCCCGGATGGGCGGCTTCATGATGGGCGCGTACTTCGTCGCCACGGGCGTCTCTCAATA
TCTCGGCAGCGTCGTCGCGAACTTCGCGCAGATGCCGTCGAACGATCTGCCCGCGACCGCGTCGCTGCCGCTCTACATCG
AGCTGTTCACGGGCCTCGGCTGGCTCGCGGCGGCCGGCATGGCGATCGGCCTGCTGATGCTGCCGCTGATGAACAAGCTG
TCGCGCGAGCATCACCGCTGCGAAGCGCAGCGCCGCGAAACGCAGGCGCTCGCCGCGCATTAA

Upstream 100 bases:

>100_bases
CGCCCGGCCGCGCCGGCCGCCGCGCCGCGGCCGGCGTCTTGCCCACCATCCGTCGCGCCGCCGCGCGCGGCGTTTCGTCC
GTTCAATCCAGAGGTGCACA

Downstream 100 bases:

>100_bases
AGGCTCGCCTGCGCGAGACCCTGGGATCTCGCGCAGGCGAATGCCCGCAAGCGCTCGTCCGGCAAGAAGCGAGGAGCACC
GTTCGGCCGGGCCGAACGCC

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MNTRVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDKLRFTDGQANLTWGAFTALVYASPSIGGWIGDKVLGARRSMI
IGAVVLCAGYLMLAIPNDQLAFMYTSLGVIVVGNGLFKSNAANLVRRIYEGDNARIDSAFTIYYMAVNIGSTASMLATPW
IKDHWGWHTAFAVCCAGMALGILNFVLMHRTLAHIGSQPDAQPVHWRRLAAVAAGGVALGLATMYVLGHKQLAVASVWVA
AFAILAIFAYMIAKSNRAERSGLIAALLLIAQVILFFIFYVQMQTSLTLFALRNVDPRFMLFGTTLFTWSPAQFQALNPI
WIMLLSPVLVAIYNGLGKRGRDLPVAGKYALGFGVVALGYLAFSISGRFAVDGRVSSWFMVAGYGFYSLGELLVSGLGLA
MIARYVPARMGGFMMGAYFVATGVSQYLGSVVANFAQMPSNDLPATASLPLYIELFTGLGWLAAAGMAIGLLMLPLMNKL
SREHHRCEAQRRETQALAAH

Sequences:

>Translated_500_residues
MNTRVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDKLRFTDGQANLTWGAFTALVYASPSIGGWIGDKVLGARRSMI
IGAVVLCAGYLMLAIPNDQLAFMYTSLGVIVVGNGLFKSNAANLVRRIYEGDNARIDSAFTIYYMAVNIGSTASMLATPW
IKDHWGWHTAFAVCCAGMALGILNFVLMHRTLAHIGSQPDAQPVHWRRLAAVAAGGVALGLATMYVLGHKQLAVASVWVA
AFAILAIFAYMIAKSNRAERSGLIAALLLIAQVILFFIFYVQMQTSLTLFALRNVDPRFMLFGTTLFTWSPAQFQALNPI
WIMLLSPVLVAIYNGLGKRGRDLPVAGKYALGFGVVALGYLAFSISGRFAVDGRVSSWFMVAGYGFYSLGELLVSGLGLA
MIARYVPARMGGFMMGAYFVATGVSQYLGSVVANFAQMPSNDLPATASLPLYIELFTGLGWLAAAGMAIGLLMLPLMNKL
SREHHRCEAQRRETQALAAH
>Mature_500_residues
MNTRVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDKLRFTDGQANLTWGAFTALVYASPSIGGWIGDKVLGARRSMI
IGAVVLCAGYLMLAIPNDQLAFMYTSLGVIVVGNGLFKSNAANLVRRIYEGDNARIDSAFTIYYMAVNIGSTASMLATPW
IKDHWGWHTAFAVCCAGMALGILNFVLMHRTLAHIGSQPDAQPVHWRRLAAVAAGGVALGLATMYVLGHKQLAVASVWVA
AFAILAIFAYMIAKSNRAERSGLIAALLLIAQVILFFIFYVQMQTSLTLFALRNVDPRFMLFGTTLFTWSPAQFQALNPI
WIMLLSPVLVAIYNGLGKRGRDLPVAGKYALGFGVVALGYLAFSISGRFAVDGRVSSWFMVAGYGFYSLGELLVSGLGLA
MIARYVPARMGGFMMGAYFVATGVSQYLGSVVANFAQMPSNDLPATASLPLYIELFTGLGWLAAAGMAIGLLMLPLMNKL
SREHHRCEAQRRETQALAAH

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=404, Percent_Identity=23.019801980198, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI226371746, Length=346, Percent_Identity=23.9884393063584, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787922, Length=478, Percent_Identity=39.1213389121339, Blast_Score=352, Evalue=3e-98,
Organism=Escherichia coli, GI1789911, Length=494, Percent_Identity=36.8421052631579, Blast_Score=338, Evalue=3e-94,
Organism=Escherichia coli, GI1786927, Length=503, Percent_Identity=29.4234592445328, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1790572, Length=476, Percent_Identity=30.8823529411765, Blast_Score=180, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71987453, Length=406, Percent_Identity=22.4137931034483, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569141, Length=373, Percent_Identity=25.7372654155496, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54391; Mature: 54391

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDKLRFTDGQANLTWGAFTALVYA
CCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SPSIGGWIGDKVLGARRSMIIGAVVLCAGYLMLAIPNDQLAFMYTSLGVIVVGNGLFKSN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCEEEEECCCHHHH
AANLVRRIYEGDNARIDSAFTIYYMAVNIGSTASMLATPWIKDHWGWHTAFAVCCAGMAL
HHHHHHHHHCCCCCEECCEEEEEEEEEECCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
GILNFVLMHRTLAHIGSQPDAQPVHWRRLAAVAAGGVALGLATMYVLGHKQLAVASVWVA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHH
AFAILAIFAYMIAKSNRAERSGLIAALLLIAQVILFFIFYVQMQTSLTLFALRNVDPRFM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEE
LFGTTLFTWSPAQFQALNPIWIMLLSPVLVAIYNGLGKRGRDLPVAGKYALGFGVVALGY
EEECHHEEECCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LAFSISGRFAVDGRVSSWFMVAGYGFYSLGELLVSGLGLAMIARYVPARMGGFMMGAYFV
HHHHCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGVSQYLGSVVANFAQMPSNDLPATASLPLYIELFTGLGWLAAAGMAIGLLMLPLMNKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
SREHHRCEAQRRETQALAAH
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTRVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDKLRFTDGQANLTWGAFTALVYA
CCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SPSIGGWIGDKVLGARRSMIIGAVVLCAGYLMLAIPNDQLAFMYTSLGVIVVGNGLFKSN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCEEEEECCCHHHH
AANLVRRIYEGDNARIDSAFTIYYMAVNIGSTASMLATPWIKDHWGWHTAFAVCCAGMAL
HHHHHHHHHCCCCCEECCEEEEEEEEEECCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
GILNFVLMHRTLAHIGSQPDAQPVHWRRLAAVAAGGVALGLATMYVLGHKQLAVASVWVA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHH
AFAILAIFAYMIAKSNRAERSGLIAALLLIAQVILFFIFYVQMQTSLTLFALRNVDPRFM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEE
LFGTTLFTWSPAQFQALNPIWIMLLSPVLVAIYNGLGKRGRDLPVAGKYALGFGVVALGY
EEECHHEEECCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LAFSISGRFAVDGRVSSWFMVAGYGFYSLGELLVSGLGLAMIARYVPARMGGFMMGAYFV
HHHHCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGVSQYLGSVVANFAQMPSNDLPATASLPLYIELFTGLGWLAAAGMAIGLLMLPLMNKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
SREHHRCEAQRRETQALAAH
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA