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The map label for this gene is thrB

Identifier: 126446815

GI number: 126446815

Start: 295909

End: 296904

Strand: Reverse

Name: thrB

Synonym: BMA10247_A0338

Alternate gene names: 126446815

Gene position: 296904-295909 (Counterclockwise)

Preceding gene: 126447150

Following gene: 126446133

Centisome position: 12.62

GC content: 68.98

Gene sequence:

>996_bases
ATGGCCGTTTTCACCGCAGTTTCCGACGCTGACCTCGCACTCTGGATGCGCCACTACGATCTCGGCGACGTTGTCGCGTT
CCGCGGCATTCCGTCCGGCATCGAGAACAGCAACTTCTTCCTGACGACGACGCGCGGCGAATACGTGCTCACGATCTTCG
AGAACCTGACGGCCGGGCAATTGCCGTTCTACGTCGATCTGATGAGCCATCTCGCGAAGCACGGGGTGCCCGTGCCCGCG
CCCGTCGCGCGCGACGACGGCACGCTGTTCGGCGAGTTGCACGGCAAGCCGGCCGCGATCGTCACCAAGCTCGAGGGCGC
GGCGCAGCTCGCGCCGGGCGTCGAGCACTGCGTCGAAGTCGGGCAGATGCTCGCGCGCATGCACCTCGCGGGCCGCGACT
ATCCGCGGCATCAGCCCAACTTGCGCAGCCTGCCGTGGTGGCGCGACACGGTGCCCGCGATCGCGCCGTTCGTCACGGGC
GAGCAGCGCGCGCTGCTGGAAGGCGAGCTCGCGCACCAGGCCGCGTTCTTCGCATCGGACGATTACGCGGCGCTGCCGGA
AGGCCCGTGCCATTGCGACCTGTTTCGCGACAATGCGCTCTTCGCGCACGCGGAGCCCGACACCGGCCATTCGGTGCGGC
TCGGCGGCTTCTTCGATTTCTACTTCGCCGGCTGCGACAAATGGCTGTTCGACGTCGCGGTGACGGTCAACGACTGGTGC
GTCGATCTGCCGACGGGCGCGCTCGACGCCGCGCGCGCCGACGCGCTGCTGCGCGCGTACCAGACGGTGCGCCCGTTCAC
CGCGGGCGAGCGCCGCCGCTGGGGCGACATGCTGCGCGCGGGCGCGTACCGCTTCTGGGTATCGCGCCTGTATGATTTCC
ACCTTCCCCGCGCCGCGCAGATGCTCAAGCCGCACGACCCGGGCCATTTCGAACGCATCCTGCGCGAACGCATCGCGCAC
GCGGGCGCGCTCCCCGAGACCCACGCATGCAACTGA

Upstream 100 bases:

>100_bases
CTATTGACGCACCGCCGGCGCCGCGCGGCGCCGGCCCCCTTCCGCCCTTTTGCGACACCGGCACGCCGCCGGCGCGCCAA
CCCGAACCGACGTTTCCTGC

Downstream 100 bases:

>100_bases
TCGAAGTCTCCGCCAAGACCGGCTACGTGTGGTTCCGCCAAGGCATCTGGCTGTTCCGGCGCAATCCGCTCGCATTCGTC
ACACTGTTCTTCACGTACCT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQLPFYVDLMSHLAKHGVPVPA
PVARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEVGQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTG
EQRALLEGELAHQAAFFASDDYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
VDLPTGALDAARADALLRAYQTVRPFTAGERRRWGDMLRAGAYRFWVSRLYDFHLPRAAQMLKPHDPGHFERILRERIAH
AGALPETHACN

Sequences:

>Translated_331_residues
MAVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQLPFYVDLMSHLAKHGVPVPA
PVARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEVGQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTG
EQRALLEGELAHQAAFFASDDYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
VDLPTGALDAARADALLRAYQTVRPFTAGERRRWGDMLRAGAYRFWVSRLYDFHLPRAAQMLKPHDPGHFERILRERIAH
AGALPETHACN
>Mature_330_residues
AVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQLPFYVDLMSHLAKHGVPVPAP
VARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEVGQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTGE
QRALLEGELAHQAAFFASDDYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWCV
DLPTGALDAARADALLRAYQTVRPFTAGERRRWGDMLRAGAYRFWVSRLYDFHLPRAAQMLKPHDPGHFERILRERIAHA
GALPETHACN

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_BURM7 (A3MBA7)

Other databases:

- EMBL:   CP000547
- RefSeq:   YP_001077543.1
- ProteinModelPortal:   A3MBA7
- SMR:   A3MBA7
- GeneID:   4890794
- GenomeReviews:   CP000547_GR
- KEGG:   bmn:BMA10247_A0338
- TIGR:   BMA10247_A0338
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   BMAL320389:BMA10247_A0338-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 36779; Mature: 36648

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQ
CEEEEECCCCHHHHHHHHCCCHHHHEECCCCCCCCCCCEEEEECCCCEEEEEECCCCCCC
LPFYVDLMSHLAKHGVPVPAPVARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEV
CHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHCCHHHHHHHH
GQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTGEQRALLEGELAHQAAFFASD
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
DYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
CCCCCCCCCCEEEEEECCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEECCEE
VDLPTGALDAARADALLRAYQTVRPFTAGERRRWGDMLRAGAYRFWVSRLYDFHLPRAAQ
EECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MLKPHDPGHFERILRERIAHAGALPETHACN
HCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQ
EEEEECCCCHHHHHHHHCCCHHHHEECCCCCCCCCCCEEEEECCCCEEEEEECCCCCCC
LPFYVDLMSHLAKHGVPVPAPVARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEV
CHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHCCHHHHHHHH
GQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTGEQRALLEGELAHQAAFFASD
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
DYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
CCCCCCCCCCEEEEEECCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEECCEE
VDLPTGALDAARADALLRAYQTVRPFTAGERRRWGDMLRAGAYRFWVSRLYDFHLPRAAQ
EECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MLKPHDPGHFERILRERIAHAGALPETHACN
HCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA