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The map label for this gene is gatA1 [H]

Identifier: 126446400

GI number: 126446400

Start: 2284495

End: 2286081

Strand: Reverse

Name: gatA1 [H]

Synonym: BMA10247_A2352

Alternate gene names: 126446400

Gene position: 2286081-2284495 (Counterclockwise)

Preceding gene: 126445602

Following gene: 126445990

Centisome position: 97.17

GC content: 74.73

Gene sequence:

>1587_bases
ATGAAACGACGGCAATTCCTTCACACGCTCGGCGCGCTGGGCCCGACGCACGCCCTGCTCGCGAGCGCGCCCGCCTCGGC
CGGGCAGACCGCGCTCGACGAGCGCGCCGGCGCATCGGCGCCCGCGCCGCCGCACGATGCGGCGCCCGCGTCGCGGGCGG
TGCGCGAATCGCTCGAGCGCATCGCGCGGATCGATCGCGACGGCCCGCGCCTGAACGCGATCATCGAATTGAATCCGGAT
GCCGAAGCGATCGCGCATGCGCTCGACGCCGAGCGGGCCGCGGGCGTCGCGCGCGGCCCGCTGCACGGCGTGACCGTCGC
GTTGAAGGACAACATCGCGACGGGCGACCGGATGTCGACGACGGCCGGCTCGCTCGCGCTCGACGGCGTGCGCGCGACGC
GCGATGCGCATCTCGTCGCGCGGCTGCGGCGCGCGGGGGCGGTGATCGTCGCGAAGGCCAACCTGAGCGAATGGGCGAAC
TTCCGCTCGACGCGCTCGACGAGCGGCTGGAGCGCGCGCGGCGGGCTGTCGCGCAACCCGTACGCGCTCGACCGGACGAC
GAGCGGATCGAGCTCCGGCTCGGCGGCGGCGGTGGCGGCGGGGCTCGTCGCCGTCTCGGTCGGCACCGAGACCGACGGCT
CGATCGTGTCGCCCGCCGCGATCAACGGCTGCGTCGGCCTGAAGCCGACGCTTGGGCGCGTGAGCCGAGACGGGATCGTG
CCGGTGTCGCACACGCAGGACACGGCGGGGCCGATCGCGCGCACGGTCCGCGACGCGGCGCGGCTGCTCGGCGCGCTCGC
GGGCGGCGACGCGCGCGACTCCGCAACGGCGAGCGCGCCCGCGCCGGCGGACTACGTCGCCGCGCTCGATGCGAATGCGC
TGCGCGGCGCGCGGCTCGGCATCGCGCGCGCGTACTTCACCGGGCACGACGAGGTGGACGTGCAGATCGAGCGCGCGATC
GCCGAGATGAAGCGGCTCGGCGCGGTCGTGATCGACCCGGTCGATCTGCCGAAAGCCGATTACGAGGAAGACGAGAAGGT
CGTGCTGCTGCACGAGTTCAAGCACGGCTTGCCGTCGTGGTTGCGGACGTTCGCGCCGCACGCGCGCGTGCGCACGCTCG
CCGACGTGATCGCGTTCAACGCGCGGCAGCATGCGCGGGAGATGCCGTATTTCGGGCAGGAGCTGCTGCTGCACGCGCAG
GAGGCGGGCGGGCTCGACGCCGCCGCGTACCGCGACGCGCTCGCCCGTTGCGGCCGCCGCGCGCGCGACGAGGGGCTCGC
GCGCGTGCTGCGCGAGCACCGGCTCGACGCGCTCGTCGCGCCGACCGAGGGCAACGCTTGGCTGATCGACCTGATCAACG
GCGACAGCGGCGGCGACGGCTTTTCGACGCCCGCCGCGGTCGCGGGTTTTCCGCATCTGACCGTGCCCGCCGGGCTCGTG
CGCGGCTTGCCGGTCGGCGTATCGTTCGTCGGCGCGCCGTGGAGCGAGGCGCGGCTGCTCGCGCTCGGCTACGCGTTCGA
GCAGGCCACGCAGTGGCGGCGCGAGCCGCGGTTCGTCGAGCGCTCGAACGTGCCGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
ACACTCCACCCACGCGCGCGCTCGCCGGACACGGCGGCGCGCCGCACGCGCGGCCGGCGTCCGGCCGCGCGGCCGCATCA
CGACAACAGGACGTACCGGA

Downstream 100 bases:

>100_bases
ACCGGTTGACGCCGAGCCACCCCGCAGGCCGCGTCGAGGCGCGGCGGGCGCGCCCGCATGCGCCGCCCCGGCGATCGCCG
TCGGCGCGCGGGATGCCGGC

Product: amidase

Products: NA

Alternate protein names: Glu-ADT subunit A 1 [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MKRRQFLHTLGALGPTHALLASAPASAGQTALDERAGASAPAPPHDAAPASRAVRESLERIARIDRDGPRLNAIIELNPD
AEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMSTTAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWAN
FRSTRSTSGWSARGGLSRNPYALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLGIARAYFTGHDEVDVQIERAI
AEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSWLRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQ
EAGGLDAAAYRDALARCGRRARDEGLARVLREHRLDALVAPTEGNAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR

Sequences:

>Translated_528_residues
MKRRQFLHTLGALGPTHALLASAPASAGQTALDERAGASAPAPPHDAAPASRAVRESLERIARIDRDGPRLNAIIELNPD
AEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMSTTAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWAN
FRSTRSTSGWSARGGLSRNPYALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLGIARAYFTGHDEVDVQIERAI
AEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSWLRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQ
EAGGLDAAAYRDALARCGRRARDEGLARVLREHRLDALVAPTEGNAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR
>Mature_528_residues
MKRRQFLHTLGALGPTHALLASAPASAGQTALDERAGASAPAPPHDAAPASRAVRESLERIARIDRDGPRLNAIIELNPD
AEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMSTTAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWAN
FRSTRSTSGWSARGGLSRNPYALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLGIARAYFTGHDEVDVQIERAI
AEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSWLRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQ
EAGGLDAAAYRDALARCGRRARDEGLARVLREHRLDALVAPTEGNAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=506, Percent_Identity=29.2490118577075, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI195972892, Length=220, Percent_Identity=30.9090909090909, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17543272, Length=426, Percent_Identity=26.7605633802817, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17537465, Length=316, Percent_Identity=26.5822784810127, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17556264, Length=214, Percent_Identity=30.8411214953271, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323950, Length=504, Percent_Identity=24.6031746031746, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319685, Length=236, Percent_Identity=33.4745762711864, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648113, Length=477, Percent_Identity=30.188679245283, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356731, Length=263, Percent_Identity=30.7984790874525, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24644968, Length=482, Percent_Identity=27.1784232365145, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI161078093, Length=479, Percent_Identity=25.678496868476, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648435, Length=221, Percent_Identity=30.316742081448, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648437, Length=221, Percent_Identity=30.316742081448, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550774, Length=221, Percent_Identity=30.316742081448, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648441, Length=173, Percent_Identity=31.7919075144509, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648439, Length=173, Percent_Identity=31.7919075144509, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652985, Length=238, Percent_Identity=33.1932773109244, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922090, Length=238, Percent_Identity=33.1932773109244, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652981, Length=238, Percent_Identity=33.1932773109244, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652983, Length=238, Percent_Identity=33.1932773109244, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 55349; Mature: 55349

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRQFLHTLGALGPTHALLASAPASAGQTALDERAGASAPAPPHDAAPASRAVRESLER
CCHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
IARIDRDGPRLNAIIELNPDAEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMST
HHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCC
TAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWANFRSTRSTSGWSARGGLSRNP
CCCCCEECCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCC
YALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
EEEECCCCCCCCCCHHHHHHHHHEEEECCCCCCCEECCHHHCCCCCCCCCCCCCCCCCCE
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLG
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCHHHH
IARAYFTGHDEVDVQIERAIAEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSW
HHHHEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEHHHHCCHHHH
LRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQEAGGLDAAAYRDALARCGRR
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ARDEGLARVLREHRLDALVAPTEGNAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHH
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR
CCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
>Mature Secondary Structure
MKRRQFLHTLGALGPTHALLASAPASAGQTALDERAGASAPAPPHDAAPASRAVRESLER
CCHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
IARIDRDGPRLNAIIELNPDAEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMST
HHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCC
TAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWANFRSTRSTSGWSARGGLSRNP
CCCCCEECCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCC
YALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
EEEECCCCCCCCCCHHHHHHHHHEEEECCCCCCCEECCHHHCCCCCCCCCCCCCCCCCCE
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLG
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCHHHH
IARAYFTGHDEVDVQIERAIAEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSW
HHHHEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEHHHHCCHHHH
LRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQEAGGLDAAAYRDALARCGRR
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ARDEGLARVLREHRLDALVAPTEGNAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHH
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR
CCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]