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The map label for this gene is iorB [H]

Identifier: 126446323

GI number: 126446323

Start: 1480270

End: 1482501

Strand: Direct

Name: iorB [H]

Synonym: BMA10247_A1531

Alternate gene names: 126446323

Gene position: 1480270-1482501 (Clockwise)

Preceding gene: 126447776

Following gene: 126447098

Centisome position: 62.92

GC content: 72.63

Gene sequence:

>2232_bases
ATGACGACCGACCTCGATCTCCCGGACGCCGTGCGCGCGTCCCGCCGCACGTTCCTGAAAGCCGCCGGCGCCGCCGCGGC
CGTCGGCCTCACGATCGGCTTCGAGTGGCTCGACGCGAGCCGCCCGGCGCTCGGCGCGACCGCGCCGGCCGCACCCGCCG
GCGACGCGGCCGGCGCGTTCGCGCCGAACGCGTTCCTGCGCGTCGCGCCGGACAACAGCGTGACCGTGATCGCGAAGCAC
GTCGAAATGGGCCAGGGCGCGTACACCGGCATCGCGACGATCGTCGCCGAAGAGCTCGACGCGAACTGGCGCGACGTGCG
CGTCGAGAGCGCGCCCGCCGACGCGTCGCGCTACGCGAACCTGCAGTTCGGCAAGCTGCAGGGCACGGGCGGCAGCTCGG
CGATGGCGAACTCGTGGATGCAACTGCGCGAGGCGGGCGCGAAGGCGCGTGCGATGCTCGTGTCCGCGGCCGCCGCGCAA
TGGAACGTGCCCGCCGCCGAGCTGACGACGGGCGACGGCGTCGTGCGCCACGCGGCGAGCCGGCGCGAGGCCACCTACGG
CTCGCTCGCGACCGCCGCGGCCGCGCTGCCCGTGCCGGAGCAGGTCGCGCTGAAGTCGCCGAGCGATTTCCGGCTGATCG
GCAAGCCGGTGCCGCGTGTCGACGCGCGCGCGAAATCCGACGGCACCGCGCAGTTCACGATCGACGTGTCGATGCCCGGC
ATGCTCGTCGCGCTGCTGCAGCGCCCGCCCGTCTTCGGCGGCAAGGTGAAATCGTTCGACGCGAGCGCGGCGAAGGCGGT
GCCGGGCGTCGTGTCGGTCGTGCAGGTCGAGCGCAGCGTGGCGGTCGTCGCGAAGGGTTTCTGGGCCGCGAAGCAAGGCC
GCGACGCGCTGAAGGTCGAATGGGACGAATCGGGCGCGGAGAAGCGCAGCTCCGACGCGATCATGCGCGAGTACCGGCAG
CTCGCCGAGCGCCCGGGCGCGTCCGCGCGCCGCGACGGCGATGCCGAGCACGCGCTCGCCGGCGCGGCGAAGCGGCTCCG
CGCGTCGTACGAGTTCCCGTACCCCGCGCACGCGCCGATGGAGCCGCTCGACGCGGTCGTCAAGCTGAGCGCCGATCGCT
GCGAGATCTGGGCGGGCGACCAGTTCCAGACGATCGACCAGGGCAACGCGGCGCGCGTCGCGGGGCTCGATCCGTCGCAG
GTCCAGATCCACACGTTGTATGCGGGCGGCAGCTTCGGCCGGCGCGCGAACGCGTGGTCGGACTACGTCGTCGAGGCCGT
GTCGATCGCGAAGGCGCTCGGCGCGAACGGCACGCCCGTCAAGCTGCAATGGACGCGCGAGGACGACATCCACGGCGGCC
TCTATCGGCCGATGTACTTCCACAGGCTCGACGCGGCGCTGTCGAAGGACGGCAAGCTCGTCGGCTGGCGGCACCGGATC
GTCGGCCAGTCGATCCTCGCCGGCACGCCGTTCGAGGCGGTGATGGTGAAGAACGGCATCGACCAGACCTCCGTCGAGGG
CGCGGCGAACCTGCCTTACGCGATCCCGAACGTATCGGTCGAGCTGACGACGACGCGATCCGCCGTGCCCGTGCTGTGGT
GGCGCGTGGTCGGCAGCTCGCACACCGCGTATGCGGTCGAGGCGTTCATCGACGAGGCCGCGCACGCGGCCGGCAAGGAT
CCGTACCTGTTCCGCCGCGACCTGCTCGCGCACGCGCCGCGCCTGAAGGGCGTGCTCGAGCTCGCCGCCGAGAAGGCCGG
CTGGGACCCGGGCAAGCCGCTGCCGAAGGGCCGCGGGCGCGGGATCGCCGTCGCCGAGGCGTTCAAGAGCTATGTCGCGC
AGGTCGCCGAAGTGTCCGTCGACGAGCACGGCGCCGTGAAGGTCGAGCGCGTCGTCTGCGCGCTCGATTGCGGCACCGCG
ATCAACCCGGACGTGATCGCCGCGCAGATGGAAGGCGGCATCGGCTTCGGGCTCGGCGCGGTGCTGCACGGCGCGATCAC
GCTGAAGGACGGCAAGGTCGAGCAGAACAACTTCGACGGCTACCGCGTGCTGCGGATCGCCGAGATGCCGAAGGTCGAGG
TGTACATCGTGCCGTCGGGCGAGGCGCCGACGGGCGTCGGCGAGCCGGGCGTCGCGCCGATCGGCCCGGCCGTCGCGAAC
GCGATCTTCGCGGCGACGGGCAAGCGCCATTACGCGCTGCCGTTCCCGGCGGCGGGAGAGGCCACGGCCTGA

Upstream 100 bases:

>100_bases
ACATCGACGCCGCGATGAACGACAACATCTGCCGTTGCGCGACCTACACCCGCATCCGCGCCGCGATTCACGAAGCGGCC
GCCACCCTGAAGGCCTGACG

Downstream 100 bases:

>100_bases
CGGGCGCGCGGCGACCGGCGGCGGCGGTCGGCGACGCGCGCCGCCGGTCGGCCGCCGTCGGCCCTGCCGGCCGGCGGCCC
CGCGAAACCGCCGGCGCGCC

Product: isoquinoline 1-oxidoreductase, beta subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MTTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAFAPNAFLRVAPDNSVTVIAKH
VEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYANLQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQ
WNVPAAELTTGDGVVRHAASRREATYGSLATAAAALPVPEQVALKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVSMPG
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVSVVQVERSVAVVAKGFWAAKQGRDALKVEWDESGAEKRSSDAIMREYRQ
LAERPGASARRDGDAEHALAGAAKRLRASYEFPYPAHAPMEPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQ
VQIHTLYAGGSFGRRANAWSDYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHRLDAALSKDGKLVGWRHRI
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSSHTAYAVEAFIDEAAHAAGKD
PYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGRGIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTA
INPDVIAAQMEGGIGFGLGAVLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
AIFAATGKRHYALPFPAAGEATA

Sequences:

>Translated_743_residues
MTTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAFAPNAFLRVAPDNSVTVIAKH
VEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYANLQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQ
WNVPAAELTTGDGVVRHAASRREATYGSLATAAAALPVPEQVALKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVSMPG
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVSVVQVERSVAVVAKGFWAAKQGRDALKVEWDESGAEKRSSDAIMREYRQ
LAERPGASARRDGDAEHALAGAAKRLRASYEFPYPAHAPMEPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQ
VQIHTLYAGGSFGRRANAWSDYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHRLDAALSKDGKLVGWRHRI
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSSHTAYAVEAFIDEAAHAAGKD
PYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGRGIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTA
INPDVIAAQMEGGIGFGLGAVLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
AIFAATGKRHYALPFPAAGEATA
>Mature_742_residues
TTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAFAPNAFLRVAPDNSVTVIAKHV
EMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYANLQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQW
NVPAAELTTGDGVVRHAASRREATYGSLATAAAALPVPEQVALKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVSMPGM
LVALLQRPPVFGGKVKSFDASAAKAVPGVVSVVQVERSVAVVAKGFWAAKQGRDALKVEWDESGAEKRSSDAIMREYRQL
AERPGASARRDGDAEHALAGAAKRLRASYEFPYPAHAPMEPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQV
QIHTLYAGGSFGRRANAWSDYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHRLDAALSKDGKLVGWRHRIV
GQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSSHTAYAVEAFIDEAAHAAGKDP
YLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGRGIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTAI
NPDVIAAQMEGGIGFGLGAVLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVANA
IFAATGKRHYALPFPAAGEATA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 78058; Mature: 77927

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAF
CCCCCCCCHHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
APNAFLRVAPDNSVTVIAKHVEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYAN
CCCCEEEECCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCC
LQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQWNVPAAELTTGDGVVRHAAS
EEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHH
RREATYGSLATAAAALPVPEQVALKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVSMPG
HHHCHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCH
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVSVVQVERSVAVVAKGFWAAKQGRDALKVE
HHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
WDESGAEKRSSDAIMREYRQLAERPGASARRDGDAEHALAGAAKRLRASYEFPYPAHAPM
ECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
EPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQVQIHTLYAGGSFGRRANAWS
CHHHHHHHCCCCCEEEECCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCHH
DYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHRLDAALSKDGKLVGWRHRI
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHH
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSS
HCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCEECCCCEEEEEECCCCHHEEEEEECCCC
HTAYAVEAFIDEAAHAAGKDPYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTAINPDVIAAQMEGGIGFGLGA
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHH
VLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
HHHCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
AIFAATGKRHYALPFPAAGEATA
HHHHHCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
TTDLDLPDAVRASRRTFLKAAGAAAAVGLTIGFEWLDASRPALGATAPAAPAGDAAGAF
CCCCCCCHHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
APNAFLRVAPDNSVTVIAKHVEMGQGAYTGIATIVAEELDANWRDVRVESAPADASRYAN
CCCCEEEECCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCC
LQFGKLQGTGGSSAMANSWMQLREAGAKARAMLVSAAAAQWNVPAAELTTGDGVVRHAAS
EEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHH
RREATYGSLATAAAALPVPEQVALKSPSDFRLIGKPVPRVDARAKSDGTAQFTIDVSMPG
HHHCHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCH
MLVALLQRPPVFGGKVKSFDASAAKAVPGVVSVVQVERSVAVVAKGFWAAKQGRDALKVE
HHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
WDESGAEKRSSDAIMREYRQLAERPGASARRDGDAEHALAGAAKRLRASYEFPYPAHAPM
ECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
EPLDAVVKLSADRCEIWAGDQFQTIDQGNAARVAGLDPSQVQIHTLYAGGSFGRRANAWS
CHHHHHHHCCCCCEEEECCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCHH
DYVVEAVSIAKALGANGTPVKLQWTREDDIHGGLYRPMYFHRLDAALSKDGKLVGWRHRI
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHH
VGQSILAGTPFEAVMVKNGIDQTSVEGAANLPYAIPNVSVELTTTRSAVPVLWWRVVGSS
HCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCEECCCCEEEEEECCCCHHEEEEEECCCC
HTAYAVEAFIDEAAHAAGKDPYLFRRDLLAHAPRLKGVLELAAEKAGWDPGKPLPKGRGR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GIAVAEAFKSYVAQVAEVSVDEHGAVKVERVVCALDCGTAINPDVIAAQMEGGIGFGLGA
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHH
VLHGAITLKDGKVEQNNFDGYRVLRIAEMPKVEVYIVPSGEAPTGVGEPGVAPIGPAVAN
HHHCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
AIFAATGKRHYALPFPAAGEATA
HHHHHCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]