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The map label for this gene is nreB [H]

Identifier: 126446293

GI number: 126446293

Start: 1397889

End: 1399367

Strand: Reverse

Name: nreB [H]

Synonym: BMA10247_A1432

Alternate gene names: 126446293

Gene position: 1399367-1397889 (Counterclockwise)

Preceding gene: 126445658

Following gene: 126446058

Centisome position: 59.48

GC content: 67.0

Gene sequence:

>1479_bases
ATGAGTTCGCCGTCGAAAAACGTCGAGATCCTGCTGGTCGAGGACAGCGTGACCGATGCACTGCTCATCGGCGAGGCGCT
GATCGACGTGACGGAGTTCGCGCCGCACGTGGTCAACGCCGAGCTGCTGTCGGCGGCGCTCGAATGCACGAAACGCGCGC
ACTTCGATGTGGTGCTGCTCGATCTCGGCTTGCCCGACGCGCACGGGCTCGATACGTTCCGCCAGTTTCATCGGCAGGTG
CCCGACGTTCCGGTGCTCGTGCTGACGGGGCTCGACGACCTGTCCGTCGGGCTGCAGGCGATTCAGGAGGGCGCGCAGGA
CTATCTGCTGAAAAAGCGCGTCGAGACGCCGTTGCTGAGCCGGGCGATACGTTATGCGATGGAGCGGCACCGCGTCGCCG
CGGCGCTCGCGGCGAGCGAGGAGCGCTTCCAGCTCGCGGTCAGCGGCGCGAGCGCGGGGCTGTGGGACTGGAATCCGAAG
ACGGGCGCGATGTACCTGTCGCCGCACTTCAAGAAGATCATGGGCTACGAGGACCATGAGCTGCCCGACGAGATCACCGG
GCATCGGGAATCGATTCATCCGGACGACCTGAAGCGCGTGCTCGACGCGCTGAAGGCGCACCTCGAGCATCGCGACACGT
ACGACGTCGAATACCGGGTGCGCACGCGCTCGGGCGATTACCGCTGGATCCAGTCGCGCGGCCAGGCGCTGTGGAACAGC
GCGGGCGAGCCGTACCGGATGGTCGGCTGGATCATGGACGTCACCGATCGCAAGCGCGACGAGGACGCGCTGCGGGTGTC
GCGCGAGGAGCTGCGCCGCCTGTCCGCGCACATCCAGAGCATTCGGGAAGAAGAGAAAACGCGCATCGCGCGGGAATTGC
ACGACGATCTCGGCCAGCAACTGACGGCGCTGAAGATGGCCGTCACGCTCGTCGACAACGAACTGAAGGACGCGGGCTGG
GCCTCGCGCACGAGCCGTTTGCCGAACGTCTATGCGTTGATCGGCCAGTTGCTGGACTCGGTGCGGCGGATTGCGGCGGA
CCTGCGCCCCGTGATGCTCGACGATCTCGGGCTGATGGCGGCGATCGAATGGCTGACGCACGAGTTCGTCGAGCGATACC
GGATTCCGGTGACGAGCCGCATCGAAGCCGACGACATCGCGTTCACCCGCGGCAGCGCGACCGAAGTGTTCCGCATCGTG
CAGGAGGCGCTGACCAATGTCGCGCGGCATTCGGAGGCGACCGAAGTCACGCTCGACATCATTCGCGACGAGCCGAACTG
CATCGTGCGGATCGCCGATAACGGTTGCGGCACCGCGCGCGATACGCGTCCGAACCGGCACTCGCTCGGCCTGCTCGGCA
TGCGCGAGCGCGCGGCGCGCCTCGGCGGCGAGATCCGGATCGACACCGCGCCCGGCCGGGGCTTCGCGTTGACGGCGACG
CTGCCGCTTGCCGTGATCGAGGCGGCCGATTCGGCCTGA

Upstream 100 bases:

>100_bases
GCTATATCACGAAGCCCGTCGATTTCGCGAAATTCACGGACGTCGTGCACAGCATCAACGAATTCTGGCTCAGCGTCGTC
ACGTTGCCGCCCGCCAAGTC

Downstream 100 bases:

>100_bases
CGGCGCCGCATCGGCAGCGGCGCGGCATCGGCTACGGCGATTCGCGGGCGACGGCGTCGACGCCGGCGTTGCCGCGGCGC
TCAGTTCGCCGCCGCGCCCG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSSPSKNVEILLVEDSVTDALLIGEALIDVTEFAPHVVNAELLSAALECTKRAHFDVVLLDLGLPDAHGLDTFRQFHRQV
PDVPVLVLTGLDDLSVGLQAIQEGAQDYLLKKRVETPLLSRAIRYAMERHRVAAALAASEERFQLAVSGASAGLWDWNPK
TGAMYLSPHFKKIMGYEDHELPDEITGHRESIHPDDLKRVLDALKAHLEHRDTYDVEYRVRTRSGDYRWIQSRGQALWNS
AGEPYRMVGWIMDVTDRKRDEDALRVSREELRRLSAHIQSIREEEKTRIARELHDDLGQQLTALKMAVTLVDNELKDAGW
ASRTSRLPNVYALIGQLLDSVRRIAADLRPVMLDDLGLMAAIEWLTHEFVERYRIPVTSRIEADDIAFTRGSATEVFRIV
QEALTNVARHSEATEVTLDIIRDEPNCIVRIADNGCGTARDTRPNRHSLGLLGMRERAARLGGEIRIDTAPGRGFALTAT
LPLAVIEAADSA

Sequences:

>Translated_492_residues
MSSPSKNVEILLVEDSVTDALLIGEALIDVTEFAPHVVNAELLSAALECTKRAHFDVVLLDLGLPDAHGLDTFRQFHRQV
PDVPVLVLTGLDDLSVGLQAIQEGAQDYLLKKRVETPLLSRAIRYAMERHRVAAALAASEERFQLAVSGASAGLWDWNPK
TGAMYLSPHFKKIMGYEDHELPDEITGHRESIHPDDLKRVLDALKAHLEHRDTYDVEYRVRTRSGDYRWIQSRGQALWNS
AGEPYRMVGWIMDVTDRKRDEDALRVSREELRRLSAHIQSIREEEKTRIARELHDDLGQQLTALKMAVTLVDNELKDAGW
ASRTSRLPNVYALIGQLLDSVRRIAADLRPVMLDDLGLMAAIEWLTHEFVERYRIPVTSRIEADDIAFTRGSATEVFRIV
QEALTNVARHSEATEVTLDIIRDEPNCIVRIADNGCGTARDTRPNRHSLGLLGMRERAARLGGEIRIDTAPGRGFALTAT
LPLAVIEAADSA
>Mature_491_residues
SSPSKNVEILLVEDSVTDALLIGEALIDVTEFAPHVVNAELLSAALECTKRAHFDVVLLDLGLPDAHGLDTFRQFHRQVP
DVPVLVLTGLDDLSVGLQAIQEGAQDYLLKKRVETPLLSRAIRYAMERHRVAAALAASEERFQLAVSGASAGLWDWNPKT
GAMYLSPHFKKIMGYEDHELPDEITGHRESIHPDDLKRVLDALKAHLEHRDTYDVEYRVRTRSGDYRWIQSRGQALWNSA
GEPYRMVGWIMDVTDRKRDEDALRVSREELRRLSAHIQSIREEEKTRIARELHDDLGQQLTALKMAVTLVDNELKDAGWA
SRTSRLPNVYALIGQLLDSVRRIAADLRPVMLDDLGLMAAIEWLTHEFVERYRIPVTSRIEADDIAFTRGSATEVFRIVQ
EALTNVARHSEATEVTLDIIRDEPNCIVRIADNGCGTARDTRPNRHSLGLLGMRERAARLGGEIRIDTAPGRGFALTATL
PLAVIEAADSA

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=195, Percent_Identity=28.7179487179487, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87082311, Length=196, Percent_Identity=33.6734693877551, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788812, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55100; Mature: 54969

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPSKNVEILLVEDSVTDALLIGEALIDVTEFAPHVVNAELLSAALECTKRAHFDVVLL
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DLGLPDAHGLDTFRQFHRQVPDVPVLVLTGLDDLSVGLQAIQEGAQDYLLKKRVETPLLS
ECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RAIRYAMERHRVAAALAASEERFQLAVSGASAGLWDWNPKTGAMYLSPHFKKIMGYEDHE
HHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCCCEEEECHHHHHHCCCCCCC
LPDEITGHRESIHPDDLKRVLDALKAHLEHRDTYDVEYRVRTRSGDYRWIQSRGQALWNS
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCC
AGEPYRMVGWIMDVTDRKRDEDALRVSREELRRLSAHIQSIREEEKTRIARELHDDLGQQ
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALKMAVTLVDNELKDAGWASRTSRLPNVYALIGQLLDSVRRIAADLRPVMLDDLGLMA
HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AIEWLTHEFVERYRIPVTSRIEADDIAFTRGSATEVFRIVQEALTNVARHSEATEVTLDI
HHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEE
IRDEPNCIVRIADNGCGTARDTRPNRHSLGLLGMRERAARLGGEIRIDTAPGRGFALTAT
EECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEEH
LPLAVIEAADSA
HHHHHHHCCCCC
>Mature Secondary Structure 
SSPSKNVEILLVEDSVTDALLIGEALIDVTEFAPHVVNAELLSAALECTKRAHFDVVLL
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DLGLPDAHGLDTFRQFHRQVPDVPVLVLTGLDDLSVGLQAIQEGAQDYLLKKRVETPLLS
ECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RAIRYAMERHRVAAALAASEERFQLAVSGASAGLWDWNPKTGAMYLSPHFKKIMGYEDHE
HHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCCCEEEECHHHHHHCCCCCCC
LPDEITGHRESIHPDDLKRVLDALKAHLEHRDTYDVEYRVRTRSGDYRWIQSRGQALWNS
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCC
AGEPYRMVGWIMDVTDRKRDEDALRVSREELRRLSAHIQSIREEEKTRIARELHDDLGQQ
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALKMAVTLVDNELKDAGWASRTSRLPNVYALIGQLLDSVRRIAADLRPVMLDDLGLMA
HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AIEWLTHEFVERYRIPVTSRIEADDIAFTRGSATEVFRIVQEALTNVARHSEATEVTLDI
HHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEE
IRDEPNCIVRIADNGCGTARDTRPNRHSLGLLGMRERAARLGGEIRIDTAPGRGFALTAT
EECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEEH
LPLAVIEAADSA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA