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The map label for this gene is rssA [H]

Identifier: 126445924

GI number: 126445924

Start: 1513457

End: 1514836

Strand: Direct

Name: rssA [H]

Synonym: BMA10247_A1571

Alternate gene names: 126445924

Gene position: 1513457-1514836 (Clockwise)

Preceding gene: 126447427

Following gene: 126447104

Centisome position: 64.33

GC content: 72.75

Gene sequence:

>1380_bases
ATGACGGGCGCGCGCGGATTCGCGCGGCGCCTGAACGCGTCGCTGCGCGGGCGGCTGCTGATGTGGCTGCTGCCCGCCGC
GTGCGTCGTCGGCGTGCTCGCGAGCACGGGCACCTATTGGGGCGCGCTGCGCGAGCTCGACGATCTGCTCGACGACCAGA
TGCGCAGCATGTCGAAGCAGATTCAGGTCGACGACGCCGGCAAGCTGTCGATCGAGGGACGTGACAGGCTCGCCAAGCGC
CATCCGGCCGACTACGATTCCGACGACGTGCTGCTGCAGGTGTGGCGCGGCGGCAAGCTCGAGTTCACGACCGACCCGGC
CACGCAACTGCCGCCGCCCGCCGCGGCCGGCTTCGTGACGCTCGACGCCGGCGGCCAGCGCTGGCACACGTACGTGCGCG
AGAGCGCGGGCACGACGATCCGCGTCGCGCAGCCGCGCCAGGCGCGCTGGGAGGCGATCGCGGGCATCGCCGTGCACCTG
CTGTGGCCGGTGCTGTCGCTGCTGCCGCTGCTCGCGATCGGGCTGTGGCTCGGCATCGGCTACGGGCTGCGCCCGCTCGG
CGCGATCGCCGCAGGCCTGAAGCGCCGCCATGCGAATCGCCTCGATCCGCTCGACATCACGACCGTGCCGACCGAGGCGC
AACCGCTCGCCTCCGAGATCAACGATCTGCTCGCGCGGCTCGATCGCTCGTTCACGCTGCAGCGCCATTTCATCGCGGAC
GCGGCGCACGAGCTGCGCACGCCGATCATGGGCCTGTCGATCCAGACGCAACTGCTGCAACGTACGGCGAGCGCCGACGA
GCGTGCGCGCATCCTCGCGCAGATTCAGGCCGGCACGACGCGCCTGTCGCATCTCGCCGAGCAATTGCTGACGCTCGCGC
GCCTCGAGCCCGAAGCGCGATCGGCGCCGTTCGCCGAGCTCGACCTCGCGGCGCTCGGCCGCTCGGTGGTCGCCGAGCGC
GCGCGCATCGCGGCCGCGCAGCACGTCGATCTCGGCGCGCTCGGCACGGCGCCCGTCCGGGTGGCCGGCAACGCGGACAC
GCTGCGCGTGCTGCTGAACAATCTCGTCGACAACGCGATCCGCTATGCGGGAGCCGGCGCGCGCGTCGACGTCGACGCGC
GCATCGACGCCGGCGGCACGCCGGTGCTCGAAGTGCGCGACAACGGCCCGGGCATTCCGGCCGCCGACCGCGAGCGCGTG
TGGGAGCGGTTCTATCGCGGCGGCGGCGCGCAGCTCGTGTCGGCGTCGGGCAGCGGGCTCGGGTTGTCGATCGTCAAGCG
CATCGCCGAACAGCATCATGCGGACGTGTCGCTCGAGGCCGGCGCCGATGGGCGCGGGCTGACGGTCACGGTGCGCTTCG
GCGCCGCGCGACAGGCGTGA

Upstream 100 bases:

>100_bases
GCAACGCGGTGCAGGTGCATATCCACAACCTGCGCAAGAAGCTCGGCCACGACACGATCCTCACGGTGCGCGGCGTCGGC
TACCGGATCGGAGACGGCGC

Downstream 100 bases:

>100_bases
GCGGTGGCGAGGCCCTTCTCGCGGGCGCTGGGTGTCGGCTGGATGGGCGTCGGTCGCTGGCGCATTGCGTGGGTTGTTGC
GGGTCGTAAGGTCGTACGTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MTGARGFARRLNASLRGRLLMWLLPAACVVGVLASTGTYWGALRELDDLLDDQMRSMSKQIQVDDAGKLSIEGRDRLAKR
HPADYDSDDVLLQVWRGGKLEFTTDPATQLPPPAAAGFVTLDAGGQRWHTYVRESAGTTIRVAQPRQARWEAIAGIAVHL
LWPVLSLLPLLAIGLWLGIGYGLRPLGAIAAGLKRRHANRLDPLDITTVPTEAQPLASEINDLLARLDRSFTLQRHFIAD
AAHELRTPIMGLSIQTQLLQRTASADERARILAQIQAGTTRLSHLAEQLLTLARLEPEARSAPFAELDLAALGRSVVAER
ARIAAAQHVDLGALGTAPVRVAGNADTLRVLLNNLVDNAIRYAGAGARVDVDARIDAGGTPVLEVRDNGPGIPAADRERV
WERFYRGGGAQLVSASGSGLGLSIVKRIAEQHHADVSLEAGADGRGLTVTVRFGAARQA

Sequences:

>Translated_459_residues
MTGARGFARRLNASLRGRLLMWLLPAACVVGVLASTGTYWGALRELDDLLDDQMRSMSKQIQVDDAGKLSIEGRDRLAKR
HPADYDSDDVLLQVWRGGKLEFTTDPATQLPPPAAAGFVTLDAGGQRWHTYVRESAGTTIRVAQPRQARWEAIAGIAVHL
LWPVLSLLPLLAIGLWLGIGYGLRPLGAIAAGLKRRHANRLDPLDITTVPTEAQPLASEINDLLARLDRSFTLQRHFIAD
AAHELRTPIMGLSIQTQLLQRTASADERARILAQIQAGTTRLSHLAEQLLTLARLEPEARSAPFAELDLAALGRSVVAER
ARIAAAQHVDLGALGTAPVRVAGNADTLRVLLNNLVDNAIRYAGAGARVDVDARIDAGGTPVLEVRDNGPGIPAADRERV
WERFYRGGGAQLVSASGSGLGLSIVKRIAEQHHADVSLEAGADGRGLTVTVRFGAARQA
>Mature_458_residues
TGARGFARRLNASLRGRLLMWLLPAACVVGVLASTGTYWGALRELDDLLDDQMRSMSKQIQVDDAGKLSIEGRDRLAKRH
PADYDSDDVLLQVWRGGKLEFTTDPATQLPPPAAAGFVTLDAGGQRWHTYVRESAGTTIRVAQPRQARWEAIAGIAVHLL
WPVLSLLPLLAIGLWLGIGYGLRPLGAIAAGLKRRHANRLDPLDITTVPTEAQPLASEINDLLARLDRSFTLQRHFIADA
AHELRTPIMGLSIQTQLLQRTASADERARILAQIQAGTTRLSHLAEQLLTLARLEPEARSAPFAELDLAALGRSVVAERA
RIAAAQHVDLGALGTAPVRVAGNADTLRVLLNNLVDNAIRYAGAGARVDVDARIDAGGTPVLEVRDNGPGIPAADRERVW
ERFYRGGGAQLVSASGSGLGLSIVKRIAEQHHADVSLEAGADGRGLTVTVRFGAARQA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=452, Percent_Identity=31.858407079646, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1790551, Length=307, Percent_Identity=30.6188925081433, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1786783, Length=287, Percent_Identity=30.3135888501742, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786600, Length=215, Percent_Identity=31.1627906976744, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=256, Percent_Identity=30.078125, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=29.4573643410853, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787894, Length=435, Percent_Identity=25.7471264367816, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=27.5229357798165, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=25.9414225941423, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=28.8617886178862, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786912, Length=203, Percent_Identity=27.0935960591133, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=27.1028037383178, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=26.8398268398268, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=23.5042735042735, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.7671232876712, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787374, Length=277, Percent_Identity=23.4657039711191, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49307; Mature: 49176

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGARGFARRLNASLRGRLLMWLLPAACVVGVLASTGTYWGALRELDDLLDDQMRSMSKQ
CCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IQVDDAGKLSIEGRDRLAKRHPADYDSDDVLLQVWRGGKLEFTTDPATQLPPPAAAGFVT
EECCCCCEEEECCHHHHHHCCCCCCCCCHHHHHEECCCEEEECCCCCCCCCCCCCCCEEE
LDAGGQRWHTYVRESAGTTIRVAQPRQARWEAIAGIAVHLLWPVLSLLPLLAIGLWLGIG
ECCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YGLRPLGAIAAGLKRRHANRLDPLDITTVPTEAQPLASEINDLLARLDRSFTLQRHFIAD
CCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHELRTPIMGLSIQTQLLQRTASADERARILAQIQAGTTRLSHLAEQLLTLARLEPEAR
HHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SAPFAELDLAALGRSVVAERARIAAAQHVDLGALGTAPVRVAGNADTLRVLLNNLVDNAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHH
RYAGAGARVDVDARIDAGGTPVLEVRDNGPGIPAADRERVWERFYRGGGAQLVSASGSGL
HHCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
GLSIVKRIAEQHHADVSLEAGADGRGLTVTVRFGAARQA
HHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TGARGFARRLNASLRGRLLMWLLPAACVVGVLASTGTYWGALRELDDLLDDQMRSMSKQ
CCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IQVDDAGKLSIEGRDRLAKRHPADYDSDDVLLQVWRGGKLEFTTDPATQLPPPAAAGFVT
EECCCCCEEEECCHHHHHHCCCCCCCCCHHHHHEECCCEEEECCCCCCCCCCCCCCCEEE
LDAGGQRWHTYVRESAGTTIRVAQPRQARWEAIAGIAVHLLWPVLSLLPLLAIGLWLGIG
ECCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YGLRPLGAIAAGLKRRHANRLDPLDITTVPTEAQPLASEINDLLARLDRSFTLQRHFIAD
CCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHELRTPIMGLSIQTQLLQRTASADERARILAQIQAGTTRLSHLAEQLLTLARLEPEAR
HHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SAPFAELDLAALGRSVVAERARIAAAQHVDLGALGTAPVRVAGNADTLRVLLNNLVDNAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHH
RYAGAGARVDVDARIDAGGTPVLEVRDNGPGIPAADRERVWERFYRGGGAQLVSASGSGL
HHCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
GLSIVKRIAEQHHADVSLEAGADGRGLTVTVRFGAARQA
HHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA