Click here to switch to the map view.

The map label for this gene is exuT [H]

Identifier: 126445851

GI number: 126445851

Start: 1583012

End: 1584352

Strand: Reverse

Name: exuT [H]

Synonym: BMA10247_A1644

Alternate gene names: 126445851

Gene position: 1584352-1583012 (Counterclockwise)

Preceding gene: 126447574

Following gene: 126446288

Centisome position: 67.34

GC content: 69.5

Gene sequence:

>1341_bases
ATGCATCAGAAAACGATGGGGTGGGTCACGGTATTCCTGCTGTTCGTCGTGTACGGCATCAATTATCTCGACCGCGTCGC
GCTGTCGATCGTCGCGCCGATGGTGCGGCGGGATCTCGGGATCGACGCCGCGCAGATGGGCGTCGTCTTCAGCACGTTCT
TCGTCGGCTATGCGCTGTTCAACTTCATCGGCGGTCTCGCGTCGGACCGGCTCGGGCCGAAGCGCGTCTATGTGATCGCC
GTGGGCCTCTGGTCGATCTTCTGCGGGATGACGGCGATCACGGTCGGCTTCGTCAGCCTGCTGATCGTGCGCCTGCTGTT
CGGCATGGCCGAGGGGCCGCTCTGCTCGGCCGCGAACAAGATGGTCAACAACTGGCTGCCGCGCGAATCGGCGGCCACGG
CGATGGGGCTGCTGAGCGCCGGCTCGCCGCTCGGCGGCGCGCTCGCCGGGCCGATCGTCGGGGTGCTCGCCGCGCAGCTC
GGCTGGCGGCCGGCGTTCTGGATCGTATGCGCGATCGGCCTCGCGTGGGTGCTCGTGTGGATCGCGACGACGTCGGACCG
GCCCGCGCCGCAGGCGTCGGCGATGCCGGCCGGCGGCTCGGGCGCCGCCGCCGCGGCGGCGCGCGCTGCGGCGGCGCCGC
GCGCGTGCGCCAGCGGCGGCCGCACCGCCGATGCCGCCCATGCCTCCGAGACCGCCGACGTGCCGCCGCTGCGCGATTAC
CTGAAGCAGCCGCGCATACTGGCGACGGGCGTCGCGTTCTTCGGCTACAACTACGTGCTGTTCTTCTTCCTGAGCTGGTT
TCCGAGCTATCTCGTGCAGGCGCATCACCTGAATATCCGCGAGATGAGCGTCGCGACGGTCGTGCCGTGGCTCGTCGGCA
CGATCGGTCTCGCGTGCGGCGGCGTGATCTCGGACGGAATCTACAAGCTCACCGGCAACGCGATGCTGTCGCGCCGAATC
GTGCTCGTCGGGTGCCTGCTCGGCGCGGGGGGCTGCGTCGCGATCGCGGGCTCGGTGCGCTCGACGCAGAGCGCGATCGC
GCTGATGTCGGTATCGCTCTTTTTCCTTTACGCGACGGGTGCGATCTACTGGGCGATCGTTCAGGACATCGTCGCGCCGG
GGCGCGTCGGCGCGGTCAGCGGCTGCCTGCACTGCATGGGAAGCCTGTCGGGCGTCATCGGGCCCGCCGTCACCGGATTC
ATCGTCGAGCGCAGCGGCTCGTTCGTGTCCGCGTTCGTGCTTGCCGGCGCGATCGCGCTCGCGGGCGCGGTGCTGTCCGC
GCTCTTCCTGCGCAACCGTGCGTGCGATGCGCGTGTGCTGCGCGAAAGTCCGCTTCTGTAG

Upstream 100 bases:

>100_bases
TTCGTCGCGCGAGCCGGATCACGTTCGATCCGCGCCGCGTCCGCGAGCGGCGGCGGCCCAACACATGAACGCCGGAGACA
TCGGCATGAAGGAGACAGGC

Downstream 100 bases:

>100_bases
GCGTGGGCGCGAGGCGTGCGGCTTGGGCGCGAATGCGGGCGGCGGCTGGATGCCGAGCAGGCCGCCCGCGCACGCGCCGT
CGCCGACGAGCGCGGTGCGG

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MHQKTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGVVFSTFFVGYALFNFIGGLASDRLGPKRVYVIA
VGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANKMVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQL
GWRPAFWIVCAIGLAWVLVWIATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASETADVPPLRDY
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACGGVISDGIYKLTGNAMLSRRI
VLVGCLLGAGGCVAIAGSVRSTQSAIALMSVSLFFLYATGAIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGF
IVERSGSFVSAFVLAGAIALAGAVLSALFLRNRACDARVLRESPLL

Sequences:

>Translated_446_residues
MHQKTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGVVFSTFFVGYALFNFIGGLASDRLGPKRVYVIA
VGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANKMVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQL
GWRPAFWIVCAIGLAWVLVWIATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASETADVPPLRDY
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACGGVISDGIYKLTGNAMLSRRI
VLVGCLLGAGGCVAIAGSVRSTQSAIALMSVSLFFLYATGAIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGF
IVERSGSFVSAFVLAGAIALAGAVLSALFLRNRACDARVLRESPLL
>Mature_446_residues
MHQKTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGVVFSTFFVGYALFNFIGGLASDRLGPKRVYVIA
VGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANKMVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQL
GWRPAFWIVCAIGLAWVLVWIATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASETADVPPLRDY
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACGGVISDGIYKLTGNAMLSRRI
VLVGCLLGAGGCVAIAGSVRSTQSAIALMSVSLFFLYATGAIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGF
IVERSGSFVSAFVLAGAIALAGAVLSALFLRNRACDARVLRESPLL

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=404, Percent_Identity=22.5247524752475, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI154350196, Length=429, Percent_Identity=23.0769230769231, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI9966811, Length=397, Percent_Identity=23.6775818639798, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI21322234, Length=413, Percent_Identity=23.0024213075061, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI9945322, Length=402, Percent_Identity=22.8855721393035, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4885441, Length=407, Percent_Identity=22.3587223587224, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI223718438, Length=213, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789152, Length=446, Percent_Identity=29.5964125560538, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI2367379, Length=435, Percent_Identity=24.5977011494253, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=28.0742459396752, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87082320, Length=421, Percent_Identity=26.8408551068884, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI2367193, Length=432, Percent_Identity=22.4537037037037, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081723, Length=268, Percent_Identity=26.1194029850746, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17552542, Length=401, Percent_Identity=24.4389027431421, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17535049, Length=424, Percent_Identity=23.3490566037736, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193205400, Length=254, Percent_Identity=24.8031496062992, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=365, Percent_Identity=23.5616438356164, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=365, Percent_Identity=23.5616438356164, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71991448, Length=389, Percent_Identity=22.879177377892, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71991453, Length=389, Percent_Identity=22.879177377892, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565914, Length=259, Percent_Identity=23.9382239382239, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=259, Percent_Identity=23.9382239382239, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641682, Length=421, Percent_Identity=23.2779097387173, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24648416, Length=402, Percent_Identity=21.6417910447761, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21356189, Length=402, Percent_Identity=21.6417910447761, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19920686, Length=423, Percent_Identity=25.531914893617, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639764, Length=375, Percent_Identity=23.7333333333333, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28573299, Length=452, Percent_Identity=22.5663716814159, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24584153, Length=369, Percent_Identity=18.970189701897, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28573708, Length=408, Percent_Identity=20.5882352941176, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573707, Length=408, Percent_Identity=20.5882352941176, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550460, Length=447, Percent_Identity=20.5816554809843, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24655255, Length=429, Percent_Identity=20.5128205128205, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580790, Length=363, Percent_Identity=20.3856749311295, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46403; Mature: 46403

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQKTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGVVFSTFFVGYALF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NFIGGLASDRLGPKRVYVIAVGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANK
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQLGWRPAFWIVCAIGLAWVLVW
HHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASETADVPPLRDY
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHCCCCCCCCCHHHHH
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GVISDGIYKLTGNAMLSRRIVLVGCLLGAGGCVAIAGSVRSTQSAIALMSVSLFFLYATG
HHHHCCHHEECCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
AIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGFIVERSGSFVSAFVLAGAIAL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AGAVLSALFLRNRACDARVLRESPLL
HHHHHHHHHHHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MHQKTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGVVFSTFFVGYALF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NFIGGLASDRLGPKRVYVIAVGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANK
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQLGWRPAFWIVCAIGLAWVLVW
HHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASETADVPPLRDY
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHCCCCCCCCCHHHHH
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GVISDGIYKLTGNAMLSRRIVLVGCLLGAGGCVAIAGSVRSTQSAIALMSVSLFFLYATG
HHHHCCHHEECCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
AIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGFIVERSGSFVSAFVLAGAIAL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AGAVLSALFLRNRACDARVLRESPLL
HHHHHHHHHHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]