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The map label for this gene is garD [H]

Identifier: 126445837

GI number: 126445837

Start: 1724370

End: 1725692

Strand: Reverse

Name: garD [H]

Synonym: BMA10247_A1789

Alternate gene names: 126445837

Gene position: 1725692-1724370 (Counterclockwise)

Preceding gene: 126446504

Following gene: 126447547

Centisome position: 73.35

GC content: 70.14

Gene sequence:

>1323_bases
ATGTCCATGACAGTTTCGACGCCGGCTTCTCCGGAGCTTTCCGCCGACGGCGTGCGCCGCGTGCTGCTCGCGGGCTATGC
GCGCAGCGACGGGCGCAAGGGCATTCGCAATGTCGTCGCGGTGGCGTATCTCGTCGAATGCGCGCATCACGTCGCGCGCG
AGATCGTCGCGCAGTTCCGCGCGCCGCCGCGCCTCGGCGACGCGGCGCCCGCCGCCGAGGCGCCGCCCGTGCACCTGATC
GGCTTTCCCGGCTGCTACCCGAACGGTTACGCGGAAAAAATGATCGAGCGGCTCGCGACGCATCCGAACGTCGGTGCGGT
GCTGTTCGTGTCGCTCGGCTGCGAGAGCATGAACAAGCACTACCTCGTCGACGCGGTGCGCGCGAGCGGCCGCCCGGCCG
AGGTGCTGACGATCCAGGAGGCGGGCGGCACGCTGAATACGATCGGCGCGGGCGTCGATTGGGTGCGCGATGCGCGCGCC
ACGCTCGCGAGGCAGGCGAAGGTGCCGATGGGCGTGGGCGAACTGATCGTCGGCACGATCTGCGGCGGCTCGGACGGCAC
GAGCGGAATCACCGCGAATCCGGCCGTCGGCCGCGCGTTCGATCTGCTCGTCGAGCAGGGCGCGGCGTGCCTGTTCGAGG
AAACGGGCGAGCTCGTCGGCTGCGAATATCACATGCAGAGCCGCGCCGCGCGCCCCGAGCTCGGCCGCGAGATCGTCGCG
TGCGTGAAGAAGGCGGAGCGCTATTACTCGATCCTCGGGCACGGCAGCTTCGCCGTCGGCAACGCGGACGGCGGGCTCAC
GACGCAGGAGGAGAAATCGCTCGGCGCGTATGCGAAGAGCGGCGCATCGCCGATCGTCGGCATCGTGAAGCCGGGCGACG
TGCCGCCGACGCCGGGCCTCTATCTGCTCGACGTCGTGCCGGACGGCGAGCCGCGTTTCGGATTCCCGAACATCAGCGAC
AACGCGGAGATCGCCGAGCTGATCGCGTGCGGCGCGCACGTGATCCTGTTCACGACGGGCCGCGGCTCGGTGGTGGGCTC
CGCGCTCGCGCCCGTCGTCAAGGTGTGCGCGAATCCGGCGACATACCGCAAGCTCGAAGGCGACATGGACGTGGACGCGG
GCCGCATTCTCGAAGGCCGCGCGACGCTCGATGAAGTCGGCCGCGAGATTTTCGCGAAGACGCTCGCCGTCGCGAGCGGC
GCGGCGTCGAAATCCGAGGCGCTCGGTCACCAGGAGTTCATCCTGACGTACAAGGCGTTCGAGCCGCTCGGGCCCGCGTG
CCTGCCTGTCGCGGGGCCGCTGCGCGCGGTGCGCCCGGCATGA

Upstream 100 bases:

>100_bases
AATCTCGTGAGCGATTACCTGCCGACGTACACGCGCGACGCGGGCCGCGCGTTCGTCGCGCATTGATGCGCACGCAACCG
TTTATTCAGGTGAACCCTTC

Downstream 100 bases:

>100_bases
GCGCGCGGGCGCGGCGGACGGCGGCGACGGTGGCCGGCGTCTTCGATATTGGGCGATCGGCGCGGCGCGCGTGTTGCGTG
AGCGCGGGCGCGGGCGGACG

Product: UxaA family hydrolase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSMTVSTPASPELSADGVRRVLLAGYARSDGRKGIRNVVAVAYLVECAHHVAREIVAQFRAPPRLGDAAPAAEAPPVHLI
GFPGCYPNGYAEKMIERLATHPNVGAVLFVSLGCESMNKHYLVDAVRASGRPAEVLTIQEAGGTLNTIGAGVDWVRDARA
TLARQAKVPMGVGELIVGTICGGSDGTSGITANPAVGRAFDLLVEQGAACLFEETGELVGCEYHMQSRAARPELGREIVA
CVKKAERYYSILGHGSFAVGNADGGLTTQEEKSLGAYAKSGASPIVGIVKPGDVPPTPGLYLLDVVPDGEPRFGFPNISD
NAEIAELIACGAHVILFTTGRGSVVGSALAPVVKVCANPATYRKLEGDMDVDAGRILEGRATLDEVGREIFAKTLAVASG
AASKSEALGHQEFILTYKAFEPLGPACLPVAGPLRAVRPA

Sequences:

>Translated_440_residues
MSMTVSTPASPELSADGVRRVLLAGYARSDGRKGIRNVVAVAYLVECAHHVAREIVAQFRAPPRLGDAAPAAEAPPVHLI
GFPGCYPNGYAEKMIERLATHPNVGAVLFVSLGCESMNKHYLVDAVRASGRPAEVLTIQEAGGTLNTIGAGVDWVRDARA
TLARQAKVPMGVGELIVGTICGGSDGTSGITANPAVGRAFDLLVEQGAACLFEETGELVGCEYHMQSRAARPELGREIVA
CVKKAERYYSILGHGSFAVGNADGGLTTQEEKSLGAYAKSGASPIVGIVKPGDVPPTPGLYLLDVVPDGEPRFGFPNISD
NAEIAELIACGAHVILFTTGRGSVVGSALAPVVKVCANPATYRKLEGDMDVDAGRILEGRATLDEVGREIFAKTLAVASG
AASKSEALGHQEFILTYKAFEPLGPACLPVAGPLRAVRPA
>Mature_439_residues
SMTVSTPASPELSADGVRRVLLAGYARSDGRKGIRNVVAVAYLVECAHHVAREIVAQFRAPPRLGDAAPAAEAPPVHLIG
FPGCYPNGYAEKMIERLATHPNVGAVLFVSLGCESMNKHYLVDAVRASGRPAEVLTIQEAGGTLNTIGAGVDWVRDARAT
LARQAKVPMGVGELIVGTICGGSDGTSGITANPAVGRAFDLLVEQGAACLFEETGELVGCEYHMQSRAARPELGREIVAC
VKKAERYYSILGHGSFAVGNADGGLTTQEEKSLGAYAKSGASPIVGIVKPGDVPPTPGLYLLDVVPDGEPRFGFPNISDN
AEIAELIACGAHVILFTTGRGSVVGSALAPVVKVCANPATYRKLEGDMDVDAGRILEGRATLDEVGREIFAKTLAVASGA
ASKSEALGHQEFILTYKAFEPLGPACLPVAGPLRAVRPA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=391, Percent_Identity=29.4117647058824, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789516, Length=401, Percent_Identity=30.6733167082294, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 45776; Mature: 45645

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTVSTPASPELSADGVRRVLLAGYARSDGRKGIRNVVAVAYLVECAHHVAREIVAQFR
CCEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APPRLGDAAPAAEAPPVHLIGFPGCYPNGYAEKMIERLATHPNVGAVLFVSLGCESMNKH
CCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECHHHCCCH
YLVDAVRASGRPAEVLTIQEAGGTLNTIGAGVDWVRDARATLARQAKVPMGVGELIVGTI
HHHHHHHCCCCCEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEEE
CGGSDGTSGITANPAVGRAFDLLVEQGAACLFEETGELVGCEYHMQSRAARPELGREIVA
ECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHCCCCHHHHHHHHH
CVKKAERYYSILGHGSFAVGNADGGLTTQEEKSLGAYAKSGASPIVGIVKPGDVPPTPGL
HHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCE
YLLDVVPDGEPRFGFPNISDNAEIAELIACGAHVILFTTGRGSVVGSALAPVVKVCANPA
EEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCH
TYRKLEGDMDVDAGRILEGRATLDEVGREIFAKTLAVASGAASKSEALGHQEFILTYKAF
HHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHEEEEEECC
EPLGPACLPVAGPLRAVRPA
CCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SMTVSTPASPELSADGVRRVLLAGYARSDGRKGIRNVVAVAYLVECAHHVAREIVAQFR
CEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APPRLGDAAPAAEAPPVHLIGFPGCYPNGYAEKMIERLATHPNVGAVLFVSLGCESMNKH
CCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECHHHCCCH
YLVDAVRASGRPAEVLTIQEAGGTLNTIGAGVDWVRDARATLARQAKVPMGVGELIVGTI
HHHHHHHCCCCCEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEEE
CGGSDGTSGITANPAVGRAFDLLVEQGAACLFEETGELVGCEYHMQSRAARPELGREIVA
ECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHCCCCHHHHHHHHH
CVKKAERYYSILGHGSFAVGNADGGLTTQEEKSLGAYAKSGASPIVGIVKPGDVPPTPGL
HHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCE
YLLDVVPDGEPRFGFPNISDNAEIAELIACGAHVILFTTGRGSVVGSALAPVVKVCANPA
EEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCH
TYRKLEGDMDVDAGRILEGRATLDEVGREIFAKTLAVASGAASKSEALGHQEFILTYKAF
HHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHEEEEEECC
EPLGPACLPVAGPLRAVRPA
CCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]