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The map label for this gene is pcaI [H]

Identifier: 126445823

GI number: 126445823

Start: 44973

End: 45821

Strand: Direct

Name: pcaI [H]

Synonym: BMA10247_A0056

Alternate gene names: 126445823

Gene position: 44973-45821 (Clockwise)

Preceding gene: 126446347

Following gene: 126446639

Centisome position: 1.91

GC content: 66.31

Gene sequence:

>849_bases
ATGATCGGCAAAACGTTCGCTAATCGAATCTGTGTTCGATATTCGAACCAATCGGATCGTCGCGCGAAGCGCGCAGCCCT
TCGCGCGAACGCGTGCCGCGGCGGGCGACGCGCGCGGATTCGCATAGGAAGAGACATGGTCAACAAGATTTTCGATTCCC
TCCAGTCGGCGGTGGCCGACGTCCACGACGGCGCGACGATCATGATCGGCGGCTTCGGCACGGCCGGGATGCCCGCCGAG
CTGATCGACGCGCTGATCGCGCAGGGCGCGCGCGATCTGACGATCGTCAACAATAACGCCGGCAACGGCGAGACGGGCCT
CGCCGCGCTGCTGAAGGCGAGGCGCGTGCGCAAGATCATCTGCTCGTTTCCGCGGCAGGCCGATTCGCAGGTGTTCGACG
CGCTGTATCGCGCGGGCGAGATCGAGCTCGAACTGGTACCGCAAGGCAACCTCGCCGAGCGGATTCGCGCGGCGGGCGCC
GGTATCGGCGGCTTCTTCTCGCCGACGGGCTACGGCACGAAGCTCGCCGAAGGCAAGGAAACGCGCGTGATCGACGGCAA
GCACTACGTGTTCGAGACGCCGATCCATGCGGATTTCGCGCTCGTGAAGGCGTACCGGGGCGACCGCTGGGGCAACCTCG
TCTATCGGAAGACCGCGCGCAATTTCGGGCCGGTGATGGCGATGGCCGCGAAGACGTCGATCGTGCAGGTGTCGCAAGTC
GTGCCGCTCGGCGCGCTGAATCCGGAACACATCGTGACGCCCGGCATCTTCGTGCAGCGCATCGTCGAAGTGCCGCAAGC
CGCGCATGCGGCCGAACTGGCGGCCGAGCGCGCGGCGAGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GTCGTTTGGCGAGGCGGCCGCCGCATGAGCGCGCCGTGCGGCGAACGCGCACGAGATGGCCGGCGGGACGTTGCCTTGAC
AATCGTGCGCACGCCCCTCT

Downstream 100 bases:

>100_bases
ATCCCCGAGGAGAACACGATGAAACGACTGACCCGCGACGACATGGCGAAGCGCGTCGCGCAAGACATCCCCGAAGGCGC
CTATGTGAACCTCGGCATCG

Product: 3-oxoadipate CoA-transferase, alpha subunit

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MIGKTFANRICVRYSNQSDRRAKRAALRANACRGGRRARIRIGRDMVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAE
LIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPRQADSQVFDALYRAGEIELELVPQGNLAERIRAAGA
GIGGFFSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAYRGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQV
VPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA

Sequences:

>Translated_282_residues
MIGKTFANRICVRYSNQSDRRAKRAALRANACRGGRRARIRIGRDMVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAE
LIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPRQADSQVFDALYRAGEIELELVPQGNLAERIRAAGA
GIGGFFSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAYRGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQV
VPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA
>Mature_282_residues
MIGKTFANRICVRYSNQSDRRAKRAALRANACRGGRRARIRIGRDMVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAE
LIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPRQADSQVFDALYRAGEIELELVPQGNLAERIRAAGA
GIGGFFSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAYRGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQV
VPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=234, Percent_Identity=42.7350427350427, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=44.206008583691, Blast_Score=191, Evalue=5e-49,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=43.9252336448598, Blast_Score=191, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=270, Percent_Identity=39.2592592592593, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI21358325, Length=270, Percent_Identity=41.4814814814815, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24655794, Length=237, Percent_Identity=44.3037974683544, Blast_Score=198, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 30268; Mature: 30268

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKTFANRICVRYSNQSDRRAKRAALRANACRGGRRARIRIGRDMVNKIFDSLQSAVAD
CCCHHHHHCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHH
VHDGATIMIGGFGTAGMPAELIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKII
HCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
CSFPRQADSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFSPTGYGTKLAEGKE
HHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
TRVIDGKHYVFETPIHADFALVKAYRGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQV
CEEECCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGKTFANRICVRYSNQSDRRAKRAALRANACRGGRRARIRIGRDMVNKIFDSLQSAVAD
CCCHHHHHCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHH
VHDGATIMIGGFGTAGMPAELIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKII
HCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
CSFPRQADSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFSPTGYGTKLAEGKE
HHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
TRVIDGKHYVFETPIHADFALVKAYRGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQV
CEEECCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]