Click here to switch to the map view.

The map label for this gene is rstB [H]

Identifier: 126445798

GI number: 126445798

Start: 1528903

End: 1530204

Strand: Reverse

Name: rstB [H]

Synonym: BMA10247_A1590

Alternate gene names: 126445798

Gene position: 1530204-1528903 (Counterclockwise)

Preceding gene: 126447190

Following gene: 126447034

Centisome position: 65.04

GC content: 69.2

Gene sequence:

>1302_bases
ATGGCGAAGCCGCTCGGCGTGCGTCGCGGTTTTACTGGACGAAACGCCGCGCCCGCTCATGTGCCGCGCGCAGGCCGGCC
GCGGACGCCGGCGCTGATGCCGATGCCCGCCGCCGATCGCCGCCGGTCCGGCCGGTTTCCGCCCGCTGACCGACGGCGCC
GCTTTCCCGATATTCGCGATCCGAACATGAACAGCACGCAAGCGCACCGATTATCCCCGTTCCGCTATCTCAAATGGCGC
TGGCTGCATTTCCGCCGCTCGTGGACGGACACGCGCGCCGACCGGATTCCGAGCTGGTCGCGCCTTTATCTGCGGACCTA
TCTGCACCTTGTCGGCCTCGTGCTGGTGACGGTCGGCGGGACGATCGCCGTGCTTTGCTCGGCGCTCGGTCCGCGCACGG
TGTGGCGCGCACTCGACGCGCTGCCGGGCGGCGCGCTGCCGCTCGCCGCGTTCGTGCTCGCGGTGCCGGCGCTCGCCGGC
TATCGATGGATGCGGCCCGTCTGGTCGGATCTCGTGATGGTGCGCGCGCGCGCGATCGATTTCACGGGCGGGCGCTTCAA
CACGCGCGCGCGCGAATCGCGCAGCGTGATCATCGGGCCGCTCGCGCGCACGCTGAACGCGCTCGCGATGCGCATGGAGC
GCCTGATCGCCACGCAGCGCGACCTGACCAACGGCATTTCGCACGAGCTGCGCACGCCGCTCGCGCGCGTGCGCTTCGCG
CTCGAGAGCCTGCGCGAGCCGGGCTCGGCCGCCGAGTATCAGAACGCGATCGACAGCATCGAGCAGGACGTGTCCGAGCT
CGACGAACTGATCGACATGAGCCTCACGTACGCGCGGCTCGAATACAGCTCGCTGCAGTCGAATCTCGAGCAGACGGCGC
TTGTCGCGTGGTTCGACAAGCAGGTCGCCGACGCCGCGCTGCTGTATCCGAGCAAGGCGATCGAAGCGCGCGTCGCGTTG
CCCGCCGAGCTGCGTGTGAAGATGGACAAGCGGCTGATGTCGTATGCGATGCGCAACCTGTTGCGCAACGCGAGCAAGCA
TGCGCGCGGGCGGATCTCGGTCGGGTTGCGGATACGCCACGGCAACATCGAGATCGACGTCGAGGACGACGGGCCCGGCG
TGCCGCCCGACGAGCGCGAGCGGATCTTCGACGCATTCGTGCGGCTCGATCGCCATACGGCGGGCTACGGGTTGGGGCTC
GCAATCACGCGGCTGGTGCTGCAGGCGCATAACGGGCGCGTCGCCGTCGTCGATCCGCTGCGGTTGCCGGGCGCGCGTTT
CGAGATGAGCTGGCCGGTGTGA

Upstream 100 bases:

>100_bases
GTGGTGCGAAATCGCGCGCGCCGCGTCGGCCACGGCGAACGCCTGTCCCGTGCCGGGCGGCGTCACGTGGCGCGGGCTTC
GCGATGCGGTGCGGCGGCGC

Downstream 100 bases:

>100_bases
TGCGCGGCGGGAAGGGGCGAGCGCGGGCGCGCCGCGGGCGGCTCGCACGCGCGTCTGGTCACGGCTGGCGGTCCGCGCCG
TCTTCTCGATCCATGCCCCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MAKPLGVRRGFTGRNAAPAHVPRAGRPRTPALMPMPAADRRRSGRFPPADRRRRFPDIRDPNMNSTQAHRLSPFRYLKWR
WLHFRRSWTDTRADRIPSWSRLYLRTYLHLVGLVLVTVGGTIAVLCSALGPRTVWRALDALPGGALPLAAFVLAVPALAG
YRWMRPVWSDLVMVRARAIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIATQRDLTNGISHELRTPLARVRFA
LESLREPGSAAEYQNAIDSIEQDVSELDELIDMSLTYARLEYSSLQSNLEQTALVAWFDKQVADAALLYPSKAIEARVAL
PAELRVKMDKRLMSYAMRNLLRNASKHARGRISVGLRIRHGNIEIDVEDDGPGVPPDERERIFDAFVRLDRHTAGYGLGL
AITRLVLQAHNGRVAVVDPLRLPGARFEMSWPV

Sequences:

>Translated_433_residues
MAKPLGVRRGFTGRNAAPAHVPRAGRPRTPALMPMPAADRRRSGRFPPADRRRRFPDIRDPNMNSTQAHRLSPFRYLKWR
WLHFRRSWTDTRADRIPSWSRLYLRTYLHLVGLVLVTVGGTIAVLCSALGPRTVWRALDALPGGALPLAAFVLAVPALAG
YRWMRPVWSDLVMVRARAIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIATQRDLTNGISHELRTPLARVRFA
LESLREPGSAAEYQNAIDSIEQDVSELDELIDMSLTYARLEYSSLQSNLEQTALVAWFDKQVADAALLYPSKAIEARVAL
PAELRVKMDKRLMSYAMRNLLRNASKHARGRISVGLRIRHGNIEIDVEDDGPGVPPDERERIFDAFVRLDRHTAGYGLGL
AITRLVLQAHNGRVAVVDPLRLPGARFEMSWPV
>Mature_432_residues
AKPLGVRRGFTGRNAAPAHVPRAGRPRTPALMPMPAADRRRSGRFPPADRRRRFPDIRDPNMNSTQAHRLSPFRYLKWRW
LHFRRSWTDTRADRIPSWSRLYLRTYLHLVGLVLVTVGGTIAVLCSALGPRTVWRALDALPGGALPLAAFVLAVPALAGY
RWMRPVWSDLVMVRARAIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIATQRDLTNGISHELRTPLARVRFAL
ESLREPGSAAEYQNAIDSIEQDVSELDELIDMSLTYARLEYSSLQSNLEQTALVAWFDKQVADAALLYPSKAIEARVALP
AELRVKMDKRLMSYAMRNLLRNASKHARGRISVGLRIRHGNIEIDVEDDGPGVPPDERERIFDAFVRLDRHTAGYGLGLA
ITRLVLQAHNGRVAVVDPLRLPGARFEMSWPV

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=310, Percent_Identity=35.8064516129032, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=32.3144104803493, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1789808, Length=283, Percent_Identity=31.095406360424, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=28.8702928870293, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=29.004329004329, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787374, Length=290, Percent_Identity=26.8965517241379, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=27.8260869565217, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790551, Length=287, Percent_Identity=25.7839721254355, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786783, Length=292, Percent_Identity=23.2876712328767, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=28.9592760180996, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=226, Percent_Identity=28.3185840707965, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48778; Mature: 48647

Theoretical pI: Translated: 11.63; Mature: 11.63

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPLGVRRGFTGRNAAPAHVPRAGRPRTPALMPMPAADRRRSGRFPPADRRRRFPDIRD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHCCCCCCC
PNMNSTQAHRLSPFRYLKWRWLHFRRSWTDTRADRIPSWSRLYLRTYLHLVGLVLVTVGG
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCH
TIAVLCSALGPRTVWRALDALPGGALPLAAFVLAVPALAGYRWMRPVWSDLVMVRARAID
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIATQRDLTNGISHELRTPLARVRFA
CCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESLREPGSAAEYQNAIDSIEQDVSELDELIDMSLTYARLEYSSLQSNLEQTALVAWFDK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADAALLYPSKAIEARVALPAELRVKMDKRLMSYAMRNLLRNASKHARGRISVGLRIRH
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
GNIEIDVEDDGPGVPPDERERIFDAFVRLDRHTAGYGLGLAITRLVLQAHNGRVAVVDPL
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCC
RLPGARFEMSWPV
CCCCCCEECCCCC
>Mature Secondary Structure 
AKPLGVRRGFTGRNAAPAHVPRAGRPRTPALMPMPAADRRRSGRFPPADRRRRFPDIRD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHCCCCCCC
PNMNSTQAHRLSPFRYLKWRWLHFRRSWTDTRADRIPSWSRLYLRTYLHLVGLVLVTVGG
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCH
TIAVLCSALGPRTVWRALDALPGGALPLAAFVLAVPALAGYRWMRPVWSDLVMVRARAID
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIATQRDLTNGISHELRTPLARVRFA
CCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESLREPGSAAEYQNAIDSIEQDVSELDELIDMSLTYARLEYSSLQSNLEQTALVAWFDK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADAALLYPSKAIEARVALPAELRVKMDKRLMSYAMRNLLRNASKHARGRISVGLRIRH
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
GNIEIDVEDDGPGVPPDERERIFDAFVRLDRHTAGYGLGLAITRLVLQAHNGRVAVVDPL
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCC
RLPGARFEMSWPV
CCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]