Click here to switch to the map view.

The map label for this gene is aceE [H]

Identifier: 126445627

GI number: 126445627

Start: 460046

End: 462769

Strand: Reverse

Name: aceE [H]

Synonym: BMA10247_A0512

Alternate gene names: 126445627

Gene position: 462769-460046 (Counterclockwise)

Preceding gene: 126446849

Following gene: 126445917

Centisome position: 19.67

GC content: 70.37

Gene sequence:

>2724_bases
ATGAACGATTTATCGAACGGAATTCGCCCGGTCCTCGCCACCGCGCGCCGCCACGACGATACCGATCCGCAGGAAACCGC
CGAATGGCTGGACGCGCTCGACGGCGTCGTCGCGCACGCGGGCGCCGAACGCGCGCAGTACCTGCTCGCGCAGCTCGCCG
AGCACGCGGCGCGACGCCGGCTCGCGCCGCCGCACGCGGGCGCGACGCCGTACGTGAACACGATCCCCGTCGACGAGGAG
CCGCCTTACCCGGGCGACCTGCAGCTCGAGGAGCGCCTCGCGGCGGTGCTGCGCTGGAACGCGCTCGCGATGGTGGTCCG
CGCGAACCGCGCATACGGCGAGCTGGGCGGCCACATCGCGAGCTACGCGTCGGCCGCCGATCTGTTCGAAGTCGGCTTCA
ACCATTTCTTCCGCGCGGCGGGCGACGCGTCGGGCGGCGATCTCGTCTACTTCCAGCCGCATTCGTCGCCGGGCGTCTAT
GCGCGCGCGTTCCTCGAAGGCTTCCTGAGCGACGCGCAGCTCGAGCACTACCGGCGCGAGATCGCCGGGCCGGGCCTGTG
CTCGTACCCGCATCCGTGGCTGATGCCCGACTTCTGGCAATTTCCGACGGGCTCGATGGGCATCGGCCCGATCAACGCGA
TCTACCAGGCGCGCTTCATGCGCTACCTGCAGAACCGCGGCCTGTTGCGCACCGAGGGCCGCAAGGTGTGGGGCTTCTTC
GGCGACGGCGAGATGGACGAGCCCGAATCGATCGGCGCGCTGTCGCTCGCCGCGCGCGAGGGGCTCGACAATCTCGTGTT
CGTGATCAACTGCAACCTGCAGCGCCTCGACGGCCCGGTGCGCGGCAACGGCCGCATCGTCGACGAGCTCGAATCGCAGT
TCGCGGGCGCCGGCTGGAACGTGATCAAGGTGCTGTGGGGCTCGGACTGGGACGCGCTGTTCGCGCGCGACGCGACGGGC
GCGCTCGCGCGCGCGTTCGCGCAAACGGTCGACGGCCAGTTCCAGACGTTCTCGGCGAACGACGGCGCGTACAACCGCGC
GCGCTTCTTCGGCCAGAACGACGCGCTCGCGGCGCTCGTCGCGCACCTGCGCGACGAGGACATCGACCGGCTGCGCCGCG
GCGGCCACGACGCGCGCAAGCTGTACGCCGCGTACGAGCGCGCGGTCCGGCACGAGGGCCGGCCGACGGTGATCCTCGCG
AAGACGATGAAGGGCTTCGGCCTGGGCGCGATCGGCCAGGGCCGGATGACGACCCACCAGCAAAAGAAGCTCGACGTCGA
GCACCTGCTCGCGTTCCGCGACCGCTTCCGGCTGCCGCTCACCGACGAAGACGTCGCGCAGCTGCGTTTCTACCGACCCG
AGAAAGACAGCCCGGAGATGCGATACCTGCATGCGCGCCGGGCTGCCCTGGGAGGCTGTCTGCCCAGAAGGCGGGCAGCG
GCGACGGCGGCATTGACCGTGCCGTCGTTGCCGTCCTGGGGGCAATTCGCGCTCGACGGCGGCCGCGAGATGTCGACGAC
GATGGCGATCGTGCGGATGCTCGGCGGTCTGCTGAAGGATGCGGCGCTCGGGCCGCGCATCGTGCCCATCGTCGCCGACG
AGGCGCGCACGTTCGGGATGGCGAACCTGTTCCGGCAGGTCGGCATCTACTCGCCGCTCGGCCAGCGCTACGAGCCCGAG
GATCTCGGCTCGATGCTCTACTACCGCGAGGACACGCGCGGGCAGATTCTCGAGGAAGGGATCTCGGAAGCGGGCGCGAT
ATCGTCGTGGATCGCCGCGGCGACATCGTACAGCGTGCACGATCTGCCGATGCTGCCGTTCTACATCTACTACTCGATGT
TCGGCTTCCAGCGGATCGGCGATCTGATCTGGGCCGCGGCCGACCAGCGCGCGCGCGGCTTCCTGATCGGCGCGACGTCG
GGCAAGACGACGCTCGGCGGCGAAGGGCTCCAGCACCAGGACGGCACGAGCCATCTCGCGGCGTCGACGGTGCCGAACTG
CCGCGCGTGGGATCCGGCGTTCGCCTACGAAATCGCGGTGATCGTCGACGAAGGAATGCGCGAGATGGTCGAGCGGCAGC
GCGACACGTTCTACTACCTGACCGTCACGAACGAGAATCACGCGCAGCCGACGCTGCCCGCGGACCGGCTCGACGCGGTG
CGCGGCGGCATCCTGAAAGGCATGTATCCGCTCGATGCGGCCGCGCTGCCCGCCGCGCGCGTGCAGTTGCTCGGCTCGGG
CGCGATTCTCGGCGAAGTGCAGGCGGCCGCGCGCCTGCTGCGCGACGATTGGCGAATCGACGCGGCCGTCTGGAGCGTGA
CGAGCTTCACCGAGCTGCAACGCGACGGCATCGCGGCCGAGCGCGCGCAGCGCCTCTTCGATGCCGACGACGCGAACGAA
CGCTCGCCGACGCCCCACGTCACGTCCGCGCTCGCCGCGACGCAAGGGCCCGTGATCGCCGCGACCGACTATGCGCGCGC
GCTGCCCGAGCTGATCCGCGCGTACGTGCCGCGCCGCTATGTGACGCTCGGCACCGACGGCTTCGGCCGCAGCGACACGC
GCGAAGCGCTGCGCGCGTTCTTCGAGGTCGATCGCGGCTCGATCGTGATCGCCGCGCTGCGCGCGCTCGCCGATGACGGG
GAGGTGACGCGCACCGTCGTGCGCGATGCGATCGCGCGATACGGCAAGCGGGACGCGTCGCGCACGCCGCCGTGGGAACG
GTGA

Upstream 100 bases:

>100_bases
TTCCAACCAAAAGAGATGCACATTCTGCGGCTCGATGGATAACCTTGATGGCTGTTGCCGCCTCAGCCGCCCCCACGAAC
CCGCCCGCCCGGAGCCGCGC

Downstream 100 bases:

>100_bases
GGCGCGAGAGAGCGCGGGCGGCGCGCGGCAGCGACGTGCGTCGCGGATCGCCTGCGCAGCGGCCGATGTCGAATCGAATC
CGGACGCCCCCGCCCAGCGC

Product: 2-oxoacid dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 907; Mature: 907

Protein sequence:

>907_residues
MNDLSNGIRPVLATARRHDDTDPQETAEWLDALDGVVAHAGAERAQYLLAQLAEHAARRRLAPPHAGATPYVNTIPVDEE
PPYPGDLQLEERLAAVLRWNALAMVVRANRAYGELGGHIASYASAADLFEVGFNHFFRAAGDASGGDLVYFQPHSSPGVY
ARAFLEGFLSDAQLEHYRREIAGPGLCSYPHPWLMPDFWQFPTGSMGIGPINAIYQARFMRYLQNRGLLRTEGRKVWGFF
GDGEMDEPESIGALSLAAREGLDNLVFVINCNLQRLDGPVRGNGRIVDELESQFAGAGWNVIKVLWGSDWDALFARDATG
ALARAFAQTVDGQFQTFSANDGAYNRARFFGQNDALAALVAHLRDEDIDRLRRGGHDARKLYAAYERAVRHEGRPTVILA
KTMKGFGLGAIGQGRMTTHQQKKLDVEHLLAFRDRFRLPLTDEDVAQLRFYRPEKDSPEMRYLHARRAALGGCLPRRRAA
ATAALTVPSLPSWGQFALDGGREMSTTMAIVRMLGGLLKDAALGPRIVPIVADEARTFGMANLFRQVGIYSPLGQRYEPE
DLGSMLYYREDTRGQILEEGISEAGAISSWIAAATSYSVHDLPMLPFYIYYSMFGFQRIGDLIWAAADQRARGFLIGATS
GKTTLGGEGLQHQDGTSHLAASTVPNCRAWDPAFAYEIAVIVDEGMREMVERQRDTFYYLTVTNENHAQPTLPADRLDAV
RGGILKGMYPLDAAALPAARVQLLGSGAILGEVQAAARLLRDDWRIDAAVWSVTSFTELQRDGIAAERAQRLFDADDANE
RSPTPHVTSALAATQGPVIAATDYARALPELIRAYVPRRYVTLGTDGFGRSDTREALRAFFEVDRGSIVIAALRALADDG
EVTRTVVRDAIARYGKRDASRTPPWER

Sequences:

>Translated_907_residues
MNDLSNGIRPVLATARRHDDTDPQETAEWLDALDGVVAHAGAERAQYLLAQLAEHAARRRLAPPHAGATPYVNTIPVDEE
PPYPGDLQLEERLAAVLRWNALAMVVRANRAYGELGGHIASYASAADLFEVGFNHFFRAAGDASGGDLVYFQPHSSPGVY
ARAFLEGFLSDAQLEHYRREIAGPGLCSYPHPWLMPDFWQFPTGSMGIGPINAIYQARFMRYLQNRGLLRTEGRKVWGFF
GDGEMDEPESIGALSLAAREGLDNLVFVINCNLQRLDGPVRGNGRIVDELESQFAGAGWNVIKVLWGSDWDALFARDATG
ALARAFAQTVDGQFQTFSANDGAYNRARFFGQNDALAALVAHLRDEDIDRLRRGGHDARKLYAAYERAVRHEGRPTVILA
KTMKGFGLGAIGQGRMTTHQQKKLDVEHLLAFRDRFRLPLTDEDVAQLRFYRPEKDSPEMRYLHARRAALGGCLPRRRAA
ATAALTVPSLPSWGQFALDGGREMSTTMAIVRMLGGLLKDAALGPRIVPIVADEARTFGMANLFRQVGIYSPLGQRYEPE
DLGSMLYYREDTRGQILEEGISEAGAISSWIAAATSYSVHDLPMLPFYIYYSMFGFQRIGDLIWAAADQRARGFLIGATS
GKTTLGGEGLQHQDGTSHLAASTVPNCRAWDPAFAYEIAVIVDEGMREMVERQRDTFYYLTVTNENHAQPTLPADRLDAV
RGGILKGMYPLDAAALPAARVQLLGSGAILGEVQAAARLLRDDWRIDAAVWSVTSFTELQRDGIAAERAQRLFDADDANE
RSPTPHVTSALAATQGPVIAATDYARALPELIRAYVPRRYVTLGTDGFGRSDTREALRAFFEVDRGSIVIAALRALADDG
EVTRTVVRDAIARYGKRDASRTPPWER
>Mature_907_residues
MNDLSNGIRPVLATARRHDDTDPQETAEWLDALDGVVAHAGAERAQYLLAQLAEHAARRRLAPPHAGATPYVNTIPVDEE
PPYPGDLQLEERLAAVLRWNALAMVVRANRAYGELGGHIASYASAADLFEVGFNHFFRAAGDASGGDLVYFQPHSSPGVY
ARAFLEGFLSDAQLEHYRREIAGPGLCSYPHPWLMPDFWQFPTGSMGIGPINAIYQARFMRYLQNRGLLRTEGRKVWGFF
GDGEMDEPESIGALSLAAREGLDNLVFVINCNLQRLDGPVRGNGRIVDELESQFAGAGWNVIKVLWGSDWDALFARDATG
ALARAFAQTVDGQFQTFSANDGAYNRARFFGQNDALAALVAHLRDEDIDRLRRGGHDARKLYAAYERAVRHEGRPTVILA
KTMKGFGLGAIGQGRMTTHQQKKLDVEHLLAFRDRFRLPLTDEDVAQLRFYRPEKDSPEMRYLHARRAALGGCLPRRRAA
ATAALTVPSLPSWGQFALDGGREMSTTMAIVRMLGGLLKDAALGPRIVPIVADEARTFGMANLFRQVGIYSPLGQRYEPE
DLGSMLYYREDTRGQILEEGISEAGAISSWIAAATSYSVHDLPMLPFYIYYSMFGFQRIGDLIWAAADQRARGFLIGATS
GKTTLGGEGLQHQDGTSHLAASTVPNCRAWDPAFAYEIAVIVDEGMREMVERQRDTFYYLTVTNENHAQPTLPADRLDAV
RGGILKGMYPLDAAALPAARVQLLGSGAILGEVQAAARLLRDDWRIDAAVWSVTSFTELQRDGIAAERAQRLFDADDANE
RSPTPHVTSALAATQGPVIAATDYARALPELIRAYVPRRYVTLGTDGFGRSDTREALRAFFEVDRGSIVIAALRALADDG
EVTRTVVRDAIARYGKRDASRTPPWER

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=894, Percent_Identity=53.1319910514541, Blast_Score=968, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 99905; Mature: 99905

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLSNGIRPVLATARRHDDTDPQETAEWLDALDGVVAHAGAERAQYLLAQLAEHAARRR
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
LAPPHAGATPYVNTIPVDEEPPYPGDLQLEERLAAVLRWNALAMVVRANRAYGELGGHIA
CCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SYASAADLFEVGFNHFFRAAGDASGGDLVYFQPHSSPGVYARAFLEGFLSDAQLEHYRRE
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IAGPGLCSYPHPWLMPDFWQFPTGSMGIGPINAIYQARFMRYLQNRGLLRTEGRKVWGFF
HCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEE
GDGEMDEPESIGALSLAAREGLDNLVFVINCNLQRLDGPVRGNGRIVDELESQFAGAGWN
CCCCCCCCHHCCHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCCCCHHHHHHHHCCCCCE
VIKVLWGSDWDALFARDATGALARAFAQTVDGQFQTFSANDGAYNRARFFGQNDALAALV
EEEEEECCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCHHHHHHH
AHLRDEDIDRLRRGGHDARKLYAAYERAVRHEGRPTVILAKTMKGFGLGAIGQGRMTTHQ
HHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCH
QKKLDVEHLLAFRDRFRLPLTDEDVAQLRFYRPEKDSPEMRYLHARRAALGGCLPRRRAA
HHHCCHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHH
ATAALTVPSLPSWGQFALDGGREMSTTMAIVRMLGGLLKDAALGPRIVPIVADEARTFGM
HHHEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
ANLFRQVGIYSPLGQRYEPEDLGSMLYYREDTRGQILEEGISEAGAISSWIAAATSYSVH
HHHHHHHCCCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DLPMLPFYIYYSMFGFQRIGDLIWAAADQRARGFLIGATSGKTTLGGEGLQHQDGTSHLA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
ASTVPNCRAWDPAFAYEIAVIVDEGMREMVERQRDTFYYLTVTNENHAQPTLPADRLDAV
HHCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
RGGILKGMYPLDAAALPAARVQLLGSGAILGEVQAAARLLRDDWRIDAAVWSVTSFTELQ
HHHHHHCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDGIAAERAQRLFDADDANERSPTPHVTSALAATQGPVIAATDYARALPELIRAYVPRRY
HCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCE
VTLGTDGFGRSDTREALRAFFEVDRGSIVIAALRALADDGEVTRTVVRDAIARYGKRDAS
EEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
RTPPWER
CCCCCCC
>Mature Secondary Structure
MNDLSNGIRPVLATARRHDDTDPQETAEWLDALDGVVAHAGAERAQYLLAQLAEHAARRR
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
LAPPHAGATPYVNTIPVDEEPPYPGDLQLEERLAAVLRWNALAMVVRANRAYGELGGHIA
CCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SYASAADLFEVGFNHFFRAAGDASGGDLVYFQPHSSPGVYARAFLEGFLSDAQLEHYRRE
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IAGPGLCSYPHPWLMPDFWQFPTGSMGIGPINAIYQARFMRYLQNRGLLRTEGRKVWGFF
HCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEE
GDGEMDEPESIGALSLAAREGLDNLVFVINCNLQRLDGPVRGNGRIVDELESQFAGAGWN
CCCCCCCCHHCCHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCCCCHHHHHHHHCCCCCE
VIKVLWGSDWDALFARDATGALARAFAQTVDGQFQTFSANDGAYNRARFFGQNDALAALV
EEEEEECCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCHHHHHHH
AHLRDEDIDRLRRGGHDARKLYAAYERAVRHEGRPTVILAKTMKGFGLGAIGQGRMTTHQ
HHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCH
QKKLDVEHLLAFRDRFRLPLTDEDVAQLRFYRPEKDSPEMRYLHARRAALGGCLPRRRAA
HHHCCHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHH
ATAALTVPSLPSWGQFALDGGREMSTTMAIVRMLGGLLKDAALGPRIVPIVADEARTFGM
HHHEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
ANLFRQVGIYSPLGQRYEPEDLGSMLYYREDTRGQILEEGISEAGAISSWIAAATSYSVH
HHHHHHHCCCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DLPMLPFYIYYSMFGFQRIGDLIWAAADQRARGFLIGATSGKTTLGGEGLQHQDGTSHLA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
ASTVPNCRAWDPAFAYEIAVIVDEGMREMVERQRDTFYYLTVTNENHAQPTLPADRLDAV
HHCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
RGGILKGMYPLDAAALPAARVQLLGSGAILGEVQAAARLLRDDWRIDAAVWSVTSFTELQ
HHHHHHCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDGIAAERAQRLFDADDANERSPTPHVTSALAATQGPVIAATDYARALPELIRAYVPRRY
HCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCE
VTLGTDGFGRSDTREALRAFFEVDRGSIVIAALRALADDGEVTRTVVRDAIARYGKRDAS
EEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
RTPPWER
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9171401; 10984043 [H]