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The map label for this gene is hpaD [H]

Identifier: 126445600

GI number: 126445600

Start: 1463835

End: 1464683

Strand: Reverse

Name: hpaD [H]

Synonym: BMA10247_A1510

Alternate gene names: 126445600

Gene position: 1464683-1463835 (Counterclockwise)

Preceding gene: 126446976

Following gene: 126446238

Centisome position: 62.26

GC content: 66.78

Gene sequence:

>849_bases
ATGGGAAAGCTGTCACTCGCCGCGAAGATCACGCACGTGCCCTCGATGTACCTGTCCGAGCTGCCGGGCAGGCATCACGG
CTGCCGCGCGGAGGCGATCCGCGGCCATCAGGCGATCGGCGAGCGCTGCCGCGCGCTCGGCGTCGATACGATCGTCGTCG
CCGATACGCACTGGCTCGTCAACGCCGGCTATCACGTGAACTGCAACGGGCATTTCGCGGGCGTCTACACGAGCAACGAG
CTGCCGCACTTCATCCGCGACATGCGCTACGAATACCCGGGCAATCCGGCGCTCGGCCATCTGATCGCGGCGAGCGCGAA
CGAGCGCGGGATCGGCACGCGCGCGCACGAGATCGACAGCCTCGAGCTCGAGTACGGCACGCTCGTGCCGATGCGCTACA
TGAACGCCGATCAGCGCTTCAAGGTCGTGTCGATCGCCGGCTGGTGCATGTGGCACGCGCTCGACGAGAGCCGCCGCTTC
GGCGAGGCGCTCAGGCACGCGATCGACGCGAGCGACGCGAACGTCGCGTTCCTCGCGAGCGGCTCGCTGTCGCACCGCTT
CAACGACAACGGCAGCCCCGAGGAGGCGATCCACATGATCAGCCGCGAGTTCTACAGGCAAGTCGACCTGCGCGTGGTCG
AGCTGTGGAAGCAGGGCGATTTCGCGACGTTCTGCAAGATGCTGCCCGAGTACAACGCGCACTGCCACGGCGAGGGCGGC
ATGCACGACACCGCGATGCTGCTCGGCCTGCTCGGCTGGGATCGCTACGACAAGCCGGTCGAGATCGTGACCGACTACTT
CGCGAGCTCGGGCACGGGGCAGATCAACGCGATCTTCCCGCTGCCGTGA

Upstream 100 bases:

>100_bases
CAGCCATCACATTCCCCGCTGGGGCGTGTGACGCCCGCCGACAACGAACGATACGCCGCGTGCCGGAGCCGTCGGCCGGC
CGCGCGGCAGGAGACTCACG

Downstream 100 bases:

>100_bases
GCGGCGCGGCGGTTCGCTTCGAGCGCCCGCGCAATCCTCGGAACAACGGAGAGCCCCATGCCTCACATCATCGTCGAATA
CACCGCGAACATTCGCGACG

Product: 3,4-dihydroxyphenylacetate 2,3-dioxygenase

Products: NA

Alternate protein names: Homoprotocatechuate 2,3-dioxygenase; HPC dioxygenase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MGKLSLAAKITHVPSMYLSELPGRHHGCRAEAIRGHQAIGERCRALGVDTIVVADTHWLVNAGYHVNCNGHFAGVYTSNE
LPHFIRDMRYEYPGNPALGHLIAASANERGIGTRAHEIDSLELEYGTLVPMRYMNADQRFKVVSIAGWCMWHALDESRRF
GEALRHAIDASDANVAFLASGSLSHRFNDNGSPEEAIHMISREFYRQVDLRVVELWKQGDFATFCKMLPEYNAHCHGEGG
MHDTAMLLGLLGWDRYDKPVEIVTDYFASSGTGQINAIFPLP

Sequences:

>Translated_282_residues
MGKLSLAAKITHVPSMYLSELPGRHHGCRAEAIRGHQAIGERCRALGVDTIVVADTHWLVNAGYHVNCNGHFAGVYTSNE
LPHFIRDMRYEYPGNPALGHLIAASANERGIGTRAHEIDSLELEYGTLVPMRYMNADQRFKVVSIAGWCMWHALDESRRF
GEALRHAIDASDANVAFLASGSLSHRFNDNGSPEEAIHMISREFYRQVDLRVVELWKQGDFATFCKMLPEYNAHCHGEGG
MHDTAMLLGLLGWDRYDKPVEIVTDYFASSGTGQINAIFPLP
>Mature_281_residues
GKLSLAAKITHVPSMYLSELPGRHHGCRAEAIRGHQAIGERCRALGVDTIVVADTHWLVNAGYHVNCNGHFAGVYTSNEL
PHFIRDMRYEYPGNPALGHLIAASANERGIGTRAHEIDSLELEYGTLVPMRYMNADQRFKVVSIAGWCMWHALDESRRFG
EALRHAIDASDANVAFLASGSLSHRFNDNGSPEEAIHMISREFYRQVDLRVVELWKQGDFATFCKMLPEYNAHCHGEGGM
HDTAMLLGLLGWDRYDKPVEIVTDYFASSGTGQINAIFPLP

Specific function: Transforms homoprotocatechuic acid (HPC) into 5- carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) [H]

COG id: COG3384

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011984
- InterPro:   IPR004183 [H]

Pfam domain/function: PF02900 LigB [H]

EC number: =1.13.11.15 [H]

Molecular weight: Translated: 31439; Mature: 31308

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLSLAAKITHVPSMYLSELPGRHHGCRAEAIRGHQAIGERCRALGVDTIVVADTHWLV
CCCCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEE
NAGYHVNCNGHFAGVYTSNELPHFIRDMRYEYPGNPALGHLIAASANERGIGTRAHEIDS
ECCEEEECCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHEEEECCCCCCCCCCHHCCCC
LELEYGTLVPMRYMNADQRFKVVSIAGWCMWHALDESRRFGEALRHAIDASDANVAFLAS
EEECCCCCCCHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GSLSHRFNDNGSPEEAIHMISREFYRQVDLRVVELWKQGDFATFCKMLPEYNAHCHGEGG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEHHHCCCHHHHHHHCCCCCCEECCCCC
MHDTAMLLGLLGWDRYDKPVEIVTDYFASSGTGQINAIFPLP
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure 
GKLSLAAKITHVPSMYLSELPGRHHGCRAEAIRGHQAIGERCRALGVDTIVVADTHWLV
CCCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEE
NAGYHVNCNGHFAGVYTSNELPHFIRDMRYEYPGNPALGHLIAASANERGIGTRAHEIDS
ECCEEEECCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHEEEECCCCCCCCCCHHCCCC
LELEYGTLVPMRYMNADQRFKVVSIAGWCMWHALDESRRFGEALRHAIDASDANVAFLAS
EEECCCCCCCHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GSLSHRFNDNGSPEEAIHMISREFYRQVDLRVVELWKQGDFATFCKMLPEYNAHCHGEGG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEHHHCCCHHHHHHHCCCCCCEECCCCC
MHDTAMLLGLLGWDRYDKPVEIVTDYFASSGTGQINAIFPLP
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2261999 [H]