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The map label for this gene is paaN [H]

Identifier: 126455462

GI number: 126455462

Start: 3480926

End: 3482632

Strand: Direct

Name: paaN [H]

Synonym: BURPS1106A_3573

Alternate gene names: 126455462

Gene position: 3480926-3482632 (Clockwise)

Preceding gene: 126452513

Following gene: 126453966

Centisome position: 87.28

GC content: 66.43

Gene sequence:

>1707_bases
ATGACCCATCCTCTGTTCACGAAGCATGAAGACACGTTGAAGCACGCGCTCTCCACGATCGAAACGCGCGGCTACTGGAG
CCCGTTCGCCGAGATGCCGAGCCCCAAAGTGTACGGGGAAAGCGCCAATACAGACGGCGAAGCAGCATTCAAAGCCCAGT
TGGACAAGCCCTTTGAACTCGACCAACCCGCCTCGGGCGGAACGGTCGGCGCCGAGCGTTCGCCATACGGGTTTGCGCTC
GGCGTCCGCTACCCGAAGTCGACGCCCGACGAGCTCATCGCCGCCGCCGCGCAGGCGGAATGCGCGTGGCGCAAGGCCGG
GCCGACCGCGTGGGCTGGCGTGTGTCTCGAAATTCTCGCCCGGCTGAATCGCGCGAGCTTCGAGATCGCATACAGCGTGA
TGCACACCACGGGACAGGCGTTCATGATGGCGTTCCAGGCGGGCGGCCCGCACGCGCAGGATCGCGCGCTCGAAGCCGTC
GCCTATGCATGGCAAGAACTGCAGCGCATTCCCGCCGAAGCGCACTGGGAGAAGCCGCAGGGCAAGAACCCGCCGCTCGC
GATGCGCAAGCGCTACACGATCGTGCCGCGCGGGACGGGGCTCGTGCTCGGGTGCTGCACGTTCCCGACCTGGAACGGCT
ATCCCGGTCTGTTCGCCGATCTGGCGACCGGCAACACAGTCATCGTCAAGCCGCATCCCGGCGCGATCCTGCCGCTCGCG
ATCACCGTGCGCATCGCGCGCGACGTGCTGCGCGAAGCGGGCTTCGATCCGAACATCGTCACGCTGCTCGCGACCGAAGG
AAACGACGGCGCACTCGTCCAGGATCTGGCGCGCCGGCCGGAAATCAAGCTGATCGACTTCACCGGCAGCTCGCAAAACG
GCACCTGGCTCGAGCGCAATGCGTACCAGGCGCAGGTCTATACGGAGAAGGCGGGCGTCAACCAGATCGTGATCGATTCC
GTCGACGACCTGAAAGCCGCCGTCAAGAACATCGCGTTCTCGCTTGCGCTCTACTCCGGCCAGATGTGCACAGCGCCGCA
AAACATCTATGTGCCGCGTGACGGCATCCGCACCGCCGAAGGGCACGTCGGCTTCGACGACGTCGCGCAGGCGATCGCCG
ACGCCGTGCAAAAGCTGACGGGCGACCCGGCACGCTCGGTCGAACTCATCGGGGCGCTGCAGAACGAAGGCGTCGCGGCA
CGTATCGACGAAGCGCGCAAGCTCGGCCGCATTCTCGCCGACAGCCAGGCGCTCGAGCACCCGGCATTCAAGGACGCGCG
CGTGCGCACGCCGCTCGTGCTGCAACTCGACGTCGCGGACCGTGCGAAGTACACGCAGGAATGGTTCGGTCCGATCTCGT
TCGTCATCGCGACCGATTCGACTGCGCAATCGCTCGATCTCGCCAGCTCGATCGCGGCCGAGCATGGCGCGCTCACGCTG
TCCGTCTATAGCACGGACGACGCCGTCGTCGAAGCGGCGCACGAAGCGGCGGTGCGCGGCGGCGTCGCGCTGTCGATCAA
TCTGACGGGCGGCGTGTTCGTCAATCAGTCGGCGGCGTTCTCCGACTTTCACGGCACGGGCGCCAATCCGGCCGCGAATG
CGTCGCTCGCCGACGCCGCGTTCGTCGCGAACCGCTTCCGCGTCGTTCAGAGCCGCCACCATGTTGCGCCGAAGGCGGCT
CCCGCGGAAGCCGGCCAAACGGCATAA

Upstream 100 bases:

>100_bases
TGCCGCACACGCACGGATGATTTGATGCTAACATTTTCCGACCAACCGGTCGGTTAATTAATGACCACCGCTTCCCTCAA
CGTTCACCAAGCCTGCCGCC

Downstream 100 bases:

>100_bases
CCCGTTCGGCCGAGCTGCCGATCGCGCGACCGTTCACTACCATGAATGAACCCGCCCGCTCGCGGGTTCACCTTTGCCGG
AATTCGACATGACCGAAGCA

Product: phenylacetic acid degradation protein paaN

Products: NA

Alternate protein names: P5C dehydrogenase [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTHPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANTDGEAAFKAQLDKPFELDQPASGGTVGAERSPYGFAL
GVRYPKSTPDELIAAAAQAECAWRKAGPTAWAGVCLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWQELQRIPAEAHWEKPQGKNPPLAMRKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
ITVRIARDVLREAGFDPNIVTLLATEGNDGALVQDLARRPEIKLIDFTGSSQNGTWLERNAYQAQVYTEKAGVNQIVIDS
VDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAEGHVGFDDVAQAIADAVQKLTGDPARSVELIGALQNEGVAA
RIDEARKLGRILADSQALEHPAFKDARVRTPLVLQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLASSIAAEHGALTL
SVYSTDDAVVEAAHEAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAAFVANRFRVVQSRHHVAPKAA
PAEAGQTA

Sequences:

>Translated_568_residues
MTHPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANTDGEAAFKAQLDKPFELDQPASGGTVGAERSPYGFAL
GVRYPKSTPDELIAAAAQAECAWRKAGPTAWAGVCLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWQELQRIPAEAHWEKPQGKNPPLAMRKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
ITVRIARDVLREAGFDPNIVTLLATEGNDGALVQDLARRPEIKLIDFTGSSQNGTWLERNAYQAQVYTEKAGVNQIVIDS
VDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAEGHVGFDDVAQAIADAVQKLTGDPARSVELIGALQNEGVAA
RIDEARKLGRILADSQALEHPAFKDARVRTPLVLQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLASSIAAEHGALTL
SVYSTDDAVVEAAHEAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAAFVANRFRVVQSRHHVAPKAA
PAEAGQTA
>Mature_567_residues
THPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANTDGEAAFKAQLDKPFELDQPASGGTVGAERSPYGFALG
VRYPKSTPDELIAAAAQAECAWRKAGPTAWAGVCLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVA
YAWQELQRIPAEAHWEKPQGKNPPLAMRKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLAI
TVRIARDVLREAGFDPNIVTLLATEGNDGALVQDLARRPEIKLIDFTGSSQNGTWLERNAYQAQVYTEKAGVNQIVIDSV
DDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAEGHVGFDDVAQAIADAVQKLTGDPARSVELIGALQNEGVAAR
IDEARKLGRILADSQALEHPAFKDARVRTPLVLQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLASSIAAEHGALTLS
VYSTDDAVVEAAHEAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAAFVANRFRVVQSRHHVAPKAAP
AEAGQTA

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Homo sapiens, GI115387104, Length=288, Percent_Identity=25, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1787250, Length=369, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787684, Length=279, Percent_Identity=26.1648745519713, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551164, Length=285, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534176, Length=305, Percent_Identity=23.9344262295082, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321828, Length=342, Percent_Identity=25.7309941520468, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320917, Length=191, Percent_Identity=31.9371727748691, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 60665; Mature: 60534

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANTDGEAAFKAQLDKPFEL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEECCCCCCCCCCHHHHHCCCCCCC
DQPASGGTVGAERSPYGFALGVRYPKSTPDELIAAAAQAECAWRKAGPTAWAGVCLEILA
CCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWQELQRIPAEAHWEKPQ
HHCCCHHHHHHHHHHHCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCC
GKNPPLAMRKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCCHHCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEECCCCCCEEHHH
ITVRIARDVLREAGFDPNIVTLLATEGNDGALVQDLARRPEIKLIDFTGSSQNGTWLERN
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEECC
AYQAQVYTEKAGVNQIVIDSVDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAE
CEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHEECCCEECCCCCEEECCCCCCCCC
GHVGFDDVAQAIADAVQKLTGDPARSVELIGALQNEGVAARIDEARKLGRILADSQALEH
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCHHHCC
PAFKDARVRTPLVLQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLASSIAAEHGALTL
CCCCCCCCCCCEEEEEECHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEE
SVYSTDDAVVEAAHEAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAA
EEECCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHH
FVANRFRVVQSRHHVAPKAAPAEAGQTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANTDGEAAFKAQLDKPFEL
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEECCCCCCCCCCHHHHHCCCCCCC
DQPASGGTVGAERSPYGFALGVRYPKSTPDELIAAAAQAECAWRKAGPTAWAGVCLEILA
CCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWQELQRIPAEAHWEKPQ
HHCCCHHHHHHHHHHHCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCC
GKNPPLAMRKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCCHHCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEECCCCCCEEHHH
ITVRIARDVLREAGFDPNIVTLLATEGNDGALVQDLARRPEIKLIDFTGSSQNGTWLERN
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEECC
AYQAQVYTEKAGVNQIVIDSVDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAE
CEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHEECCCEECCCCCEEECCCCCCCCC
GHVGFDDVAQAIADAVQKLTGDPARSVELIGALQNEGVAARIDEARKLGRILADSQALEH
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCHHHCC
PAFKDARVRTPLVLQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLASSIAAEHGALTL
CCCCCCCCCCCEEEEEECHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEE
SVYSTDDAVVEAAHEAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAA
EEECCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHH
FVANRFRVVQSRHHVAPKAAPAEAGQTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA