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The map label for this gene is dnaQ [H]

Identifier: 126455280

GI number: 126455280

Start: 1451250

End: 1452011

Strand: Reverse

Name: dnaQ [H]

Synonym: BURPS1106A_1495

Alternate gene names: 126455280

Gene position: 1452011-1451250 (Counterclockwise)

Preceding gene: 126454731

Following gene: 126452173

Centisome position: 36.41

GC content: 66.01

Gene sequence:

>762_bases
TTGCCCTTCACGACTGACTCGAATTTCCGTTTTCCCGACATGCGCCAGATCATTCTCGATACCGAAACCACCGGCCTGAA
CGCCCGCGCGGGCGACCGCATCATCGAAATCGGCTGCGTCGAGCTGCTGAACCGCCGGCTCACCGGCAAGAACCTGCACT
TCTACGTGAATCCCGAACGCGACAGCGATCCGGGCGCGCTCGCGGTGCACGGCCTCACGACCGAATTCCTGAGCGACAAG
CCGAAGTTCGCCGAAATCGTCGATCCGTTGCGCGATTTCGTCCGCGACGCGGAACTGATCATCCACAACGCGCCGTTCGA
CCTCGGCTTTCTCGACGCCGAGTTCGCGCTGCTCGGCCTGCCGTCCTTCACCGACCACTGCGCGGGCGTGATCGACACGC
TCGTGCAGGCCAAGCAAATGTTCCCGGGCAAGCGCAACTCGCTCGACGCGCTGTGCGACCGCTTCGGGATCAGCAACGCG
CACCGGACGCTGCACGGCGCGCTGCTGGACTCCGAGTTGCTCGCCGAGGTGTATCTCGCGATGACGCGCGGGCAGGAAAG
CCTCGTGATCGACATGCTCGACGAAGCCGGCGACGCGCATCGCAACGGCGACGCGCCGCGAATGGCGTTCAGCGGACTCG
ATCTGCCGGTGCTCGCCGCGACCGACGCGGAGCTCGCCGCGCACGAGGCGCAGCTCGACGCGCTCGACAAGTCGGCCAAG
GGCGTATGCGTGTGGCGCAAGGAGGCGGTCGGCGAGGCTTGA

Upstream 100 bases:

>100_bases
GAAGGGGCACGCCGGCCATCCGGAGAACGAGCGCGCGGACGCGCTCGCGAACCGCGGCGTCGAATCGCTCGCGCAGGCAT
GAGCCCGCTCGCGCCCCCCT

Downstream 100 bases:

>100_bases
GGGGTTTTGGGGTTTTGGGGTTTTGGGGTTTTGGGGTTTTGGGGTTTTGGGGTTTTGGGGTTTTGGGGTTTTGGAGCTTG
GGTGCTTCGGGCCTTCCGAC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MPFTTDSNFRFPDMRQIILDTETTGLNARAGDRIIEIGCVELLNRRLTGKNLHFYVNPERDSDPGALAVHGLTTEFLSDK
PKFAEIVDPLRDFVRDAELIIHNAPFDLGFLDAEFALLGLPSFTDHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNA
HRTLHGALLDSELLAEVYLAMTRGQESLVIDMLDEAGDAHRNGDAPRMAFSGLDLPVLAATDAELAAHEAQLDALDKSAK
GVCVWRKEAVGEA

Sequences:

>Translated_253_residues
MPFTTDSNFRFPDMRQIILDTETTGLNARAGDRIIEIGCVELLNRRLTGKNLHFYVNPERDSDPGALAVHGLTTEFLSDK
PKFAEIVDPLRDFVRDAELIIHNAPFDLGFLDAEFALLGLPSFTDHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNA
HRTLHGALLDSELLAEVYLAMTRGQESLVIDMLDEAGDAHRNGDAPRMAFSGLDLPVLAATDAELAAHEAQLDALDKSAK
GVCVWRKEAVGEA
>Mature_252_residues
PFTTDSNFRFPDMRQIILDTETTGLNARAGDRIIEIGCVELLNRRLTGKNLHFYVNPERDSDPGALAVHGLTTEFLSDKP
KFAEIVDPLRDFVRDAELIIHNAPFDLGFLDAEFALLGLPSFTDHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNAH
RTLHGALLDSELLAEVYLAMTRGQESLVIDMLDEAGDAHRNGDAPRMAFSGLDLPVLAATDAELAAHEAQLDALDKSAKG
VCVWRKEAVGEA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=53.781512605042, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27704; Mature: 27572

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFTTDSNFRFPDMRQIILDTETTGLNARAGDRIIEIGCVELLNRRLTGKNLHFYVNPER
CCCCCCCCCCCCHHHHHEEECCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEECCCC
DSDPGALAVHGLTTEFLSDKPKFAEIVDPLRDFVRDAELIIHNAPFDLGFLDAEFALLGL
CCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHEEEC
PSFTDHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNAHRTLHGALLDSELLAEVYLA
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MTRGQESLVIDMLDEAGDAHRNGDAPRMAFSGLDLPVLAATDAELAAHEAQLDALDKSAK
HHCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCC
GVCVWRKEAVGEA
CEEEEEHHCCCCC
>Mature Secondary Structure 
PFTTDSNFRFPDMRQIILDTETTGLNARAGDRIIEIGCVELLNRRLTGKNLHFYVNPER
CCCCCCCCCCCHHHHHEEECCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEECCCC
DSDPGALAVHGLTTEFLSDKPKFAEIVDPLRDFVRDAELIIHNAPFDLGFLDAEFALLGL
CCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHEEEC
PSFTDHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNAHRTLHGALLDSELLAEVYLA
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MTRGQESLVIDMLDEAGDAHRNGDAPRMAFSGLDLPVLAATDAELAAHEAQLDALDKSAK
HHCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCC
GVCVWRKEAVGEA
CEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]