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The map label for this gene is degP [H]

Identifier: 126455207

GI number: 126455207

Start: 1617844

End: 1619400

Strand: Direct

Name: degP [H]

Synonym: BURPS1106A_1664

Alternate gene names: 126455207

Gene position: 1617844-1619400 (Clockwise)

Preceding gene: 126455159

Following gene: 126453396

Centisome position: 40.56

GC content: 72.06

Gene sequence:

>1557_bases
GTGTCTCATCAAACGCTTGGCCGCGCCCTGATTCACGTTGCAGCGCTCGGGGCGGTGCTTGTCGGCTTCGCTTGCCTGCA
GCCGACGCCACTCGCCGCGGGTACGCTGCAATCGCCGGCGAAGGCGAAGCGAATCGCGCAGATCGGCGCCGCGGGGCCGG
TCGATTTTCCCACGCTCGTCGAGCGATACGGGCCCGCCGTCGTCAGCGTGAGCGTGCCTGCGCAGGATCCGCAGATGTCG
GCGTCCGGCCTCGAGGCGCTCGATCCCGACGATCCGTTCTTCGCCTACTTCAAATCCGCCGCCACGCAGCCCGCGCTGTC
GCCGGAGAACGGGCCGCGCGCGATGGCGGGCGCCGGATCCGGTTTTATCGTCGGCGCCGACGGGATCATCCTGACGACCG
CGTACGTGGTCGGGCAGGCGAGCGAGGCGACGGTTCGCCTGATCGACCGGCGCGAATTCAAGGCGCGGGTGCTGGCCGTC
GATGATTCGAGCGATGTGGCCGTGTTGCAGATCGACGCGACGAAGCTGCCGACGGTGCGGCTCGGCGATTCGTCCCGGGT
GCGCACGGGCGAGCCGGTGCTGACGATCGGCACGCCGGACGGCTCGGCGAACACGGTGACGACGGGCATCGTCAGCGCGA
CGGCGCGCATGTTGCCCGACGGCGGCCGCTTTCCGTTCTTTCAGACCGACGTGACCGGCAACCTCGACAACTCGGGCGGC
CCGGTGTTCAACCGCGCGGGCGAGGTGATCGGCATCGATGTGCAGATCTACGGCAGCGGCGAGCGCAATCCGGGCGTGAC
GTTTGCGATTCCGATCGACATGGCGATGAAGGTGCGTGCGCAGGTGCTGCAGGCGCAGCGCCAGGCGCGGCAGCAGGCGC
AGCCGCCGATGCAACAGGCGCAACAGGCGCAACAAGCGCCGCCCGCGGCGGCGCAGAACGCGCTGGGCGTCGACGCGCAG
GACGTCGGTCCGGGGCTCGCGGCGGCGTTCGGCCTGCCGCGGCCGGCGGGCGCGCTTGTCAATGCGGTGGAGCCGGGGTC
GCCGGCGGCGGCGGTCGGGCTGAAGCCGGGCGACGTGATCGTGCAGATCGGCGATCGGCCGCTCGGCCGCTCGGCGGAAC
TGGCCGGCGACCTCGCGGCGCTGCCGCCCGGGGCGAGCGCGCCGATCACGCTGATCCGCAACCGGATGCCGATGACGGTG
ATGCTCGGCTCCGGCGCGGCCGCGAGCGCGCCGACAGGCGCGACCGCATCGCCGGGCAATGCGGCCGCCGGCCGCAGCGA
GACGGGCGGCGCGGACCGCCTGGGCCTGACGATGCATCCGCTGACGGACGACGAGCGGCGCTCGACGGGATTGCCCGTCG
GCATGGTGGTCGATGCGGTGCGCGGGCCGGCGGCGAACGCGGGGATTCGGCCGGGCGACGTCGTGCTGGAGCTCGACGAT
ACGCTGATCGAGACGCCGGACATGGTGCCGGCGCTGGAGGCGAAGGCGGGGAAGGTGGTCGCGGTGCTGATTCAGCGGGG
GAGCGAGCGCAGGTTCGTGTCGGTGAAGGCGCGGTGA

Upstream 100 bases:

>100_bases
TTCGCCGGGCGCTATGCAATAATCGATTCATCAGTGCGTGCTAGTCCTTCGCGCGTCGCGCGGCGGGCCTCTGGCATAAC
GACTGCCTGGGAGGTGCACT

Downstream 100 bases:

>100_bases
AGCCGCGATGGAGGCGAAGCGCGCCGCCGGCGGTGCGCCATGCACCGGGAGCCGGCGTCGCGGCAGCGCGGCGGCGCACG
GCTCGCGCGCGGGCAATCCG

Product: peptidase s1, chymotrypsin:pdz/dhr/glgf

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSHQTLGRALIHVAALGAVLVGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLVERYGPAVVSVSVPAQDPQMS
ASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGSGFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAV
DDSSDVAVLQIDATKLPTVRLGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQAQQAQQAPPAAAQNALGVDAQ
DVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVIVQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTV
MLGSGAAASAPTGATASPGNAAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR

Sequences:

>Translated_518_residues
MSHQTLGRALIHVAALGAVLVGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLVERYGPAVVSVSVPAQDPQMS
ASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGSGFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAV
DDSSDVAVLQIDATKLPTVRLGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQAQQAQQAPPAAAQNALGVDAQ
DVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVIVQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTV
MLGSGAAASAPTGATASPGNAAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR
>Mature_517_residues
SHQTLGRALIHVAALGAVLVGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLVERYGPAVVSVSVPAQDPQMSA
SGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGSGFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAVD
DSSDVAVLQIDATKLPTVRLGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGGP
VFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQAQQAQQAPPAAAQNALGVDAQD
VGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVIVQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTVM
LGSGAAASAPTGATASPGNAAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDDT
LIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=271, Percent_Identity=35.7933579335793, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI7019477, Length=259, Percent_Identity=35.1351351351351, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI22129776, Length=274, Percent_Identity=32.4817518248175, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI24308541, Length=271, Percent_Identity=31.7343173431734, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1789629, Length=472, Percent_Identity=30.9322033898305, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786356, Length=472, Percent_Identity=28.3898305084746, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789630, Length=287, Percent_Identity=31.7073170731707, Blast_Score=132, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24646839, Length=300, Percent_Identity=31.6666666666667, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52747; Mature: 52615

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQTLGRALIHVAALGAVLVGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
ERYGPAVVSVSVPAQDPQMSASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGS
HHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCC
GFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAVDDSSDVAVLQIDATKLPTVR
CEEEECCCEEEEEEHHHCCCCCCEEEEEHHHCCEEEEEEEECCCCEEEEEECCCCCCEEE
LGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
ECCCCCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQA
CCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QQAQQAPPAAAQNALGVDAQDVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVI
HHHHHCCCHHHHHCCCCCHHHCCCCHHHHHCCCCCCHHHHCCCCCCCCCEEECCCCCCEE
VQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTVMLGSGAAASAPTGATASPGN
EEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
AAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
CCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECC
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR
HHHCCCCCCCHHHCCCCCEEEEEECCCCCCEEEEEECC
>Mature Secondary Structure 
SHQTLGRALIHVAALGAVLVGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
ERYGPAVVSVSVPAQDPQMSASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGS
HHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCC
GFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAVDDSSDVAVLQIDATKLPTVR
CEEEECCCEEEEEEHHHCCCCCCEEEEEHHHCCEEEEEEEECCCCEEEEEECCCCCCEEE
LGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
ECCCCCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQA
CCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QQAQQAPPAAAQNALGVDAQDVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVI
HHHHHCCCHHHHHCCCCCHHHCCCCHHHHHCCCCCCHHHHCCCCCCCCCEEECCCCCCEE
VQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTVMLGSGAAASAPTGATASPGN
EEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
AAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
CCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECC
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR
HHHCCCCCCCHHHCCCCCEEEEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]