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The map label for this gene is rutG [H]

Identifier: 126454961

GI number: 126454961

Start: 273641

End: 274948

Strand: Direct

Name: rutG [H]

Synonym: BURPS1106A_0291

Alternate gene names: 126454961

Gene position: 273641-274948 (Clockwise)

Preceding gene: 126453883

Following gene: 126452174

Centisome position: 6.86

GC content: 68.96

Gene sequence:

>1308_bases
ATGGCCGATTCCTATTTCCCGCGGTGGCGCGCGCAGCTGCGCGACGACGCGGCCCGCGTCATCGCCCCCGACGAGCGCCT
GCCGTGGCCGCAGACGTTCGCGATGGGCGTGCAGCACGTCGTCGCGATGTTCGGCTCGACGGTGCTCGCGCCGCTGCTGA
TGGGCTTCGATCCGAATCTCTGCATCCTGATGTCCGGGATCGGCACGCTGCTGTTCTTCGTGCTCGTCGGCGGGCGCGTG
CCGAGCTACCTCGGTTCGAGCTTCGCGTTCATCGGCCTCGTGATCGCGGTGACGGGCTATGCGGGCGGCGGCGCGAATCC
GAATGTGCCGGTCGCGCTCGGCGGGATCGTCGCGTGCGGCGTCGTCTATGCGCTGATCGGGCTCGTCGTGGCGGCCGTCG
GCACGCGCTGGATCGAGACGCTGATGCCGCCCGTCGTCACCGGCGCGATCGTCGCCGTGATCGGGCTGAACCTCGCGCCG
ATCGCGGTGAAGGGCGTGTCCGCATCGACTTTCGACGCCACGCTCGCGCTCGTGACCGTGCTGTGCGTCGGCGGTGTCGC
GGTGTTCGCGCGCGGCATGCTGCAGCGCCTGCTGATCCTCGTCGGCGTGCTGATCGCGTACGTGATCTACGCGGTGCTCA
CGAACGGCATGGGGCTCGGCAAGCCGATCGATTTCGCGATCGTCGCGCAGGCGGCATGGTTCGGCGTGCCGACGTTGCAC
CGGCCCGTGTTCGATCCGCACGCGATGCTGCTGATCGCGCCCGTCGCGGTGATCCTCGTCGCGGAAAATCTGGGTCACAT
CAAGGCGGTGAGCGCGATGACGGGCCGCAATCTCGACCGCTACGTCGGCCGCGCGTTCATCGGCGACGGCCTGGCGACGG
TCGTCTCGGCCAGCATGGGCGGCACGGGCGTGACGACGTATGCGGAGAACATCGGCGTGATGGCGGTGACGAGGATCTAC
TCGACGCTCGTGTTCGTCGCGGCCGCGCTGATCGCGATCGCGCTCGGCTTCTCGCCGAAGTTCGGCGCGGTGATCCAGAC
GATTCCGGGGCCGGTGCTGGGCGGCGTGTCGATCGTCGTGTTCGGCCTGATCGCGGTGACGGGCGCGCGGATCTGGGTCG
TGAACCGCGTCGATTTCTCGGACAACCGGAACCTGATCGTCGCCGCCGTCACGCTCGTGCTCGGCGCGGGCGACTTCTCG
CTGAAACTGGGCGGCTTCGCGCTCGGCGGGATCGGTACCGCGACGTTCGGCGCGATCCTCCTCTACGCGCTGCTGCGCAA
GGAGAAGGAGCCGGGGCCGATGGTGTGA

Upstream 100 bases:

>100_bases
CCGCTTGTCAGCGCGATTCCCGCTTCGTACACTCGCGCGTGATTTTGCCCGGACGCGCCGTCGCGCGCGCCTCAATCCAG
ACCGACAGGAGAACCCCGCG

Downstream 100 bases:

>100_bases
GCGGATGGGCGGCGGGGCGCGTCGATCGAGGTGCGCGCGGCGCGATCGCGCGACGGCCGCTTTCCGCCATCATCGGCGCC
CGATGCGCGCGAGGCTGCAA

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MADSYFPRWRAQLRDDAARVIAPDERLPWPQTFAMGVQHVVAMFGSTVLAPLLMGFDPNLCILMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYAGGGANPNVPVALGGIVACGVVYALIGLVVAAVGTRWIETLMPPVVTGAIVAVIGLNLAP
IAVKGVSASTFDATLALVTVLCVGGVAVFARGMLQRLLILVGVLIAYVIYAVLTNGMGLGKPIDFAIVAQAAWFGVPTLH
RPVFDPHAMLLIAPVAVILVAENLGHIKAVSAMTGRNLDRYVGRAFIGDGLATVVSASMGGTGVTTYAENIGVMAVTRIY
STLVFVAAALIAIALGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNRVDFSDNRNLIVAAVTLVLGAGDFS
LKLGGFALGGIGTATFGAILLYALLRKEKEPGPMV

Sequences:

>Translated_435_residues
MADSYFPRWRAQLRDDAARVIAPDERLPWPQTFAMGVQHVVAMFGSTVLAPLLMGFDPNLCILMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYAGGGANPNVPVALGGIVACGVVYALIGLVVAAVGTRWIETLMPPVVTGAIVAVIGLNLAP
IAVKGVSASTFDATLALVTVLCVGGVAVFARGMLQRLLILVGVLIAYVIYAVLTNGMGLGKPIDFAIVAQAAWFGVPTLH
RPVFDPHAMLLIAPVAVILVAENLGHIKAVSAMTGRNLDRYVGRAFIGDGLATVVSASMGGTGVTTYAENIGVMAVTRIY
STLVFVAAALIAIALGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNRVDFSDNRNLIVAAVTLVLGAGDFS
LKLGGFALGGIGTATFGAILLYALLRKEKEPGPMV
>Mature_434_residues
ADSYFPRWRAQLRDDAARVIAPDERLPWPQTFAMGVQHVVAMFGSTVLAPLLMGFDPNLCILMSGIGTLLFFVLVGGRVP
SYLGSSFAFIGLVIAVTGYAGGGANPNVPVALGGIVACGVVYALIGLVVAAVGTRWIETLMPPVVTGAIVAVIGLNLAPI
AVKGVSASTFDATLALVTVLCVGGVAVFARGMLQRLLILVGVLIAYVIYAVLTNGMGLGKPIDFAIVAQAAWFGVPTLHR
PVFDPHAMLLIAPVAVILVAENLGHIKAVSAMTGRNLDRYVGRAFIGDGLATVVSASMGGTGVTTYAENIGVMAVTRIYS
TLVFVAAALIAIALGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNRVDFSDNRNLIVAAVTLVLGAGDFSL
KLGGFALGGIGTATFGAILLYALLRKEKEPGPMV

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=428, Percent_Identity=71.0280373831776, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1788843, Length=429, Percent_Identity=39.1608391608392, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI87082181, Length=474, Percent_Identity=24.4725738396624, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790087, Length=443, Percent_Identity=25.5079006772009, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082178, Length=406, Percent_Identity=24.8768472906404, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=219, Percent_Identity=28.310502283105, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=30.3867403314917, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=168, Percent_Identity=33.9285714285714, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=168, Percent_Identity=34.5238095238095, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17542262, Length=114, Percent_Identity=35.9649122807018, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44872; Mature: 44741

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADSYFPRWRAQLRDDAARVIAPDERLPWPQTFAMGVQHVVAMFGSTVLAPLLMGFDPNL
CCCCCHHHHHHHHHCHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH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HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]