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The map label for this gene is rnhB

Identifier: 126454836

GI number: 126454836

Start: 2431222

End: 2431866

Strand: Reverse

Name: rnhB

Synonym: BURPS1106A_2478

Alternate gene names: 126454836

Gene position: 2431866-2431222 (Counterclockwise)

Preceding gene: 126454896

Following gene: 126452067

Centisome position: 60.97

GC content: 69.46

Gene sequence:

>645_bases
ATGGCGACGACGCGCAAACCCCGCGGCGGCGCCGGCGGCGCGACCCAGCCCGCGCTCGATTTCGACGCGCCGGGCGAGAT
CGTCTGCGGCGTCGACGAAGCCGGGCGCGGCCCGCTCGCCGGGCCCGTCGTCGCGGCGGCCGTCGTGCTCGATCCGGCGC
GGCCGATCGTCGGCCTCGACGATTCGAAGGCGTTGTCCGCGAAGAAGCGCGAGCGGCTCTTCGACGAAATCGTCGCGTAT
GCGCTCGCGTACAGCGTCGCCTCGGCGAGCGTCGAGGAAATCGACAGCCTCAACATCCTGCATGCGACGATGCTCGCGAT
GAAGCGCGCAGTCGAAGGGCTCTCGGTGCTGCCGACGCTCGCGAAGATCGACGGCAACCGCTGCCCGATGCTCGCGATCC
GCAGCGAAGCGATCGTCGGCGGCGACGCGCTCGTGCCGAGCATCTCGGCCGCGTCGATCCTCGCGAAGGTCACGCGCGAC
CGGATGCTCGTCGAACTGCATCAGCAGTTTCCGATGTACGGTTTCGATGCGCACGCGGGCTACGGCACGCCGCAGCATCT
GGCCGCCTTGCGCGAGCATGGGCCGTGCGAGCATCATCGCCGCTCGTTCGCGCCGGTGCGCGAAGCCTTCGATCTGATTC
GATGA

Upstream 100 bases:

>100_bases
CCGACATTTTCACCGACATGCATCTCGCGTTGCGCCAGAATACCGCGCAGCGCGCGGCCGAGGCCGTCGCGCACGTGATC
GACAGCAGGAAGCCGCGCTG

Downstream 100 bases:

>100_bases
AAGCGATCACTTCCCGCGACAATCCGCTGTACAAGCGCCTGAAGGCGCTCGCGGGATCGACGCACCAGCAGCGGCGCGGC
GAGCAGGCGCTCCTCGAAGG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVAY
ALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRD
RMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR

Sequences:

>Translated_214_residues
MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVAY
ALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRD
RMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
>Mature_213_residues
ATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVAYA
LAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDR
MLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=195, Percent_Identity=58.974358974359, Blast_Score=219, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17536263, Length=186, Percent_Identity=35.4838709677419, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_BURM7 (A3MKS8)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001080864.1
- ProteinModelPortal:   A3MKS8
- SMR:   A3MKS8
- GeneID:   4894644
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_1313
- TIGR:   BMA10247_1313
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   BMAL320389:BMA10247_1313-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22655; Mature: 22524

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
DSKALSAKKRERLFDEIVAYALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAG
HHCCCCCCCEEEECCCHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLD
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
DSKALSAKKRERLFDEIVAYALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAG
HHCCCCCCCEEEECCCHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA