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The map label for this gene is pncB [H]

Identifier: 126454646

GI number: 126454646

Start: 2828004

End: 2829203

Strand: Reverse

Name: pncB [H]

Synonym: BURPS1106A_2873

Alternate gene names: 126454646

Gene position: 2829203-2828004 (Counterclockwise)

Preceding gene: 126452900

Following gene: 126452182

Centisome position: 70.93

GC content: 62.83

Gene sequence:

>1200_bases
ATGATCATCACTTCGCTGCTCGATACCGACCTGTACAAATTCACGATGATGCAGGTCGTCCTGCATCATTTCCCGGCCGC
AAGCGTCGAATATCGCTTCAAGTGCCGCACGCCCGGCGTCGATCTCGTGCCGTACATCGACGAGATCCGCGCCGAGGTTC
GCTCGCTCTGCGAGCTGCGCTTCACCGATTCCGAGCTCGACTATCTGCGCCGGCTGCGCTTCGTCAAGAGCGATTTCGTC
GATTTTCTCGCGCTCTTTCACCTGAACGAGAAGTACATCTCGATCACGCCGTCGCAAAAGGGCGGCGGCGAGATCGACAT
CGAGATCAAGGGGCCGTGGCTGCACACGATCCTTTTCGAGATTCCGGTGCTCGCGATCGTCAACGAGGTGTACTTCCGCA
ACACGCAGCGCCGGCCGGATTACCGCGAAGGGCGCGGCCGGCTGCGCGAGAAGATCAAGCTGCTCGGCGCGAAGCCCGAA
TTCGCCGATTGCAAGATCGCCGATTACGGCACGCGCCGCCGCTTCTCGAAGGTCTGGCACGAGGAGGTGCTGCGCACGCT
GCAGGACGGGCTCGGGCCGCAGTTCGCCGGCACGAGCAACGTCTATTACGCGATGACGCACGAGATCACGCCGCTCGGCA
CGATGGCGCACGAATATCTGCAGGCGTGCCAGGCGCTCGGCCCGCGGCTGCGCGATTCGCAGACCTACGGTCTCGAGATG
TGGGCGAAGGAATATCGCGGCGATCTCGGCATCGCGCTGTCCGACGTCTACGGGATGGACGCGTTCCTGCGCGACTTCGA
CATGTACTTCTGCAAGCTCTTCGACGGCGCGCGCCACGATTCGGGCGATCCGTTCGACTGGGGCGAGCGGCTCATCAAGC
ACTACGAGGAGAACCGCTGCGACCCGCGCACGAAGGTGCTCGTGTTCTCCGACGCGCTCGATATCCCGAAGGTCATGCAG
CTGTACGCACGCTTTCGCGGACGCTGCAAGCTCGCGTTCGGCGTCGGCACGAACCTCACCAACGATCTCGGCTATCAGCC
GTTGCAGATCGTCATCAAGATGGTGCGATGCAACGGGCAGCCGGTCGCGAAGCTGTCGGATTCGCCGGGCAAGAGCATGT
GCGACGACAAGGCCTACCTCGCGTATCTGCGCCAGGTGTTCGGGATCACGCAGCCGCCCGACGACGACGCGGGCAAGTAA

Upstream 100 bases:

>100_bases
CGGCGCCGCGCCGCATTCGGGTAACATGCGTCAACCGGAGGGCGGGCGCGCGAGGCGCGCAAACGCTCGGGCTCCGTTTC
GATTTTGGCAGTCTGGAATC

Downstream 100 bases:

>100_bases
CGCCGCCCGCGCGGGTGCGGACGCGGCGCCGGGAACGCGCGTGGGCGGTCCGGCAGCGTGTTTTTCGTACCGGCGGCGGC
GGGCGTGCGCCGTCTCGGCC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRAEVRSLCELRFTDSELDYLRRLRFVKSDFV
DFLALFHLNEKYISITPSQKGGGEIDIEIKGPWLHTILFEIPVLAIVNEVYFRNTQRRPDYREGRGRLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVLRTLQDGLGPQFAGTSNVYYAMTHEITPLGTMAHEYLQACQALGPRLRDSQTYGLEM
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFDWGERLIKHYEENRCDPRTKVLVFSDALDIPKVMQ
LYARFRGRCKLAFGVGTNLTNDLGYQPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGITQPPDDDAGK

Sequences:

>Translated_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRAEVRSLCELRFTDSELDYLRRLRFVKSDFV
DFLALFHLNEKYISITPSQKGGGEIDIEIKGPWLHTILFEIPVLAIVNEVYFRNTQRRPDYREGRGRLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVLRTLQDGLGPQFAGTSNVYYAMTHEITPLGTMAHEYLQACQALGPRLRDSQTYGLEM
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFDWGERLIKHYEENRCDPRTKVLVFSDALDIPKVMQ
LYARFRGRCKLAFGVGTNLTNDLGYQPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGITQPPDDDAGK
>Mature_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRAEVRSLCELRFTDSELDYLRRLRFVKSDFV
DFLALFHLNEKYISITPSQKGGGEIDIEIKGPWLHTILFEIPVLAIVNEVYFRNTQRRPDYREGRGRLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVLRTLQDGLGPQFAGTSNVYYAMTHEITPLGTMAHEYLQACQALGPRLRDSQTYGLEM
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFDWGERLIKHYEENRCDPRTKVLVFSDALDIPKVMQ
LYARFRGRCKLAFGVGTNLTNDLGYQPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGITQPPDDDAGK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=393, Percent_Identity=43.765903307888, Blast_Score=328, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6324783, Length=417, Percent_Identity=28.537170263789, Blast_Score=193, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45962; Mature: 45962

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRAEVRSLCELR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
FTDSELDYLRRLRFVKSDFVDFLALFHLNEKYISITPSQKGGGEIDIEIKGPWLHTILFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQRRPDYREGRGRLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVLRTLQDGLGPQFAGTSNVYYAMTHEITPLGTMAHEYLQACQALGPRLRDSQTYGLEM
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFDWGERLIKHYEENRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DPRTKVLVFSDALDIPKVMQLYARFRGRCKLAFGVGTNLTNDLGYQPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGITQPPDDDAGK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRAEVRSLCELR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
FTDSELDYLRRLRFVKSDFVDFLALFHLNEKYISITPSQKGGGEIDIEIKGPWLHTILFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQRRPDYREGRGRLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVLRTLQDGLGPQFAGTSNVYYAMTHEITPLGTMAHEYLQACQALGPRLRDSQTYGLEM
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFDWGERLIKHYEENRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DPRTKVLVFSDALDIPKVMQLYARFRGRCKLAFGVGTNLTNDLGYQPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGITQPPDDDAGK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA