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The map label for this gene is eco [H]

Identifier: 126454622

GI number: 126454622

Start: 1098081

End: 1098620

Strand: Direct

Name: eco [H]

Synonym: BURPS1106A_1123

Alternate gene names: 126454622

Gene position: 1098081-1098620 (Clockwise)

Preceding gene: 126453647

Following gene: 126453123

Centisome position: 27.53

GC content: 66.85

Gene sequence:

>540_bases
ATGAAATCAGCCTCTCGCTTGGCAGCCTGGGCGGCGTATGCCGCATTCGCCGGCTATTCCGCCGTCGCGGCGGCGGCGAG
CGCGTCGACGCCCGCCGCGGGCGCCGATGCCGCGTCGTCGCCGAAGCCGGCCGTGGAAGACATCAAGATGTTCCCGGCCG
CCCAGGCGGGGCAGAAGCGCGAGGTCATCGTGCTGCCCGCCGAAAAGCTGGAAGAAGACATTCGCGTCGAACTCGTCGTC
GGCAGGACGATCAAGGTCGATTGCAATCAGCACTGGTTCGGCGGCGATCTCAAGCATGAAACGGTGCAGGGCTGGGGCTA
TCCGTACTACGTGCTCGCCGACGCGAAGGGGCCGGCCGCCACGCTGATGGCCTGCCCGGGCCAGGAATCGCAGCAGGCGT
TCGTGCCGGTGCGCGGCAGCGGCTACCTGTTGCGCTACAACAGCCGCCTGCCGATCGTCGTGTACGTGCCGAAGGAGTTC
GAGGTTCGCTACCGGTTGTGGTACGGGTCGAACGAAGTGGCGCGCGCGGTCGAGAAGTAA

Upstream 100 bases:

>100_bases
TTGTGTCCGCACATTACAATCACGTAAGCGGTCGAAGTACGGAAGCCGGCTGCGTGTCGCGTTTTTCGTTCAATTCAACA
CTCTTCTTCAGGAGCACCGT

Downstream 100 bases:

>100_bases
GCGGCGCGGCGGCTCGCTGCGATCCGCGGCGGTCGCGGCGCGACGTGCCGCGCGCGGATCGCGCCGGCGCCCCGACGGCG
GTTGCGCTGCTGCGGCGTCA

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKSASRLAAWAAYAAFAGYSAVAAAASASTPAAGADAASSPKPAVEDIKMFPAAQAGQKREVIVLPAEKLEEDIRVELVV
GRTIKVDCNQHWFGGDLKHETVQGWGYPYYVLADAKGPAATLMACPGQESQQAFVPVRGSGYLLRYNSRLPIVVYVPKEF
EVRYRLWYGSNEVARAVEK

Sequences:

>Translated_179_residues
MKSASRLAAWAAYAAFAGYSAVAAAASASTPAAGADAASSPKPAVEDIKMFPAAQAGQKREVIVLPAEKLEEDIRVELVV
GRTIKVDCNQHWFGGDLKHETVQGWGYPYYVLADAKGPAATLMACPGQESQQAFVPVRGSGYLLRYNSRLPIVVYVPKEF
EVRYRLWYGSNEVARAVEK
>Mature_179_residues
MKSASRLAAWAAYAAFAGYSAVAAAASASTPAAGADAASSPKPAVEDIKMFPAAQAGQKREVIVLPAEKLEEDIRVELVV
GRTIKVDCNQHWFGGDLKHETVQGWGYPYYVLADAKGPAATLMACPGQESQQAFVPVRGSGYLLRYNSRLPIVVYVPKEF
EVRYRLWYGSNEVARAVEK

Specific function: General inhibitor of family S1 serine proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=158, Percent_Identity=44.3037974683544, Blast_Score=137, Evalue=4e-34,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 19369; Mature: 19369

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSASRLAAWAAYAAFAGYSAVAAAASASTPAAGADAASSPKPAVEDIKMFPAAQAGQKR
CCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
EVIVLPAEKLEEDIRVELVVGRTIKVDCNQHWFGGDLKHETVQGWGYPYYVLADAKGPAA
EEEEECHHHCCCCEEEEEEECCEEEEECCCCCCCCCCCCCEECCCCCCEEEEEECCCCCE
TLMACPGQESQQAFVPVRGSGYLLRYNSRLPIVVYVPKEFEVRYRLWYGSNEVARAVEK
EEEECCCCCCCEEEEEECCCCEEEEECCCCCEEEECCCCEEEEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MKSASRLAAWAAYAAFAGYSAVAAAASASTPAAGADAASSPKPAVEDIKMFPAAQAGQKR
CCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
EVIVLPAEKLEEDIRVELVVGRTIKVDCNQHWFGGDLKHETVQGWGYPYYVLADAKGPAA
EEEEECHHHCCCCEEEEEEECCEEEEECCCCCCCCCCCCCEECCCCCCEEEEEECCCCCE
TLMACPGQESQQAFVPVRGSGYLLRYNSRLPIVVYVPKEFEVRYRLWYGSNEVARAVEK
EEEECCCCCCCEEEEEECCCCEEEEECCCCCEEEECCCCEEEEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA