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The map label for this gene is glmS [H]

Identifier: 126454525

GI number: 126454525

Start: 1415735

End: 1417666

Strand: Direct

Name: glmS [H]

Synonym: BURPS1106A_1458

Alternate gene names: 126454525

Gene position: 1415735-1417666 (Clockwise)

Preceding gene: 126451982

Following gene: 126455045

Centisome position: 35.5

GC content: 69.67

Gene sequence:

>1932_bases
ATGTGTGGAATTGTCGGCGCGGTGGCGCGGCGCGATGTCGTGCCCAACCTGGTGGACGGGCTGAAGCGGCTCGAATACCG
CGGCTACGATTCGTGCGGCGTGGTCGTCTATCAGGACCGGCGGCTCGTGCGGGCGCGCAGCGTCGATCGCGTCGCGGCAT
TGCAGCGCGAGATCTCGGCCCGCGCGTTGTCGGGCTACACGGGTATCGCGCACACGCGCTGGGCGACGCACGGCGCGCCC
GTGACGGCCAACGCGCATCCGCATTTTTCGTCGGGCGTCGCTACGTCGGGCGTCGCTACGCCGGGCGTCGCTACGTCGGG
CGCACCGGCGGCGAGCGCCGCCGCGTCCGGCGGCACCGCGCAGGCCGACGCGTCACCCGAAGCCCGCGCGCGGATCGCGC
TGTCGCACAACGGCATCATCGAGAACTACGAGGCGCTGCGCGCGGACCTCGAGCGGCACGGCTACGCGTTCGCGAGCCAG
ACCGACAGCGAGGCGATCGCGCATCTCGTCGATCATCTGTACGACGGCGACCTGTTCGACGCGGTGCGGCGCGCGCTCGC
GCGGCTGCGCGGCAGTTACGCGATCGCGGTGATGTGCCGCGACGAGCCGCACCGGATCGTCGGCGCGCGCGACGGGATGC
CGCTCGTCGTCGGCATCGGCGACGGCGAGCACTTCCTCGCGTCGGACGCGATCGCGCTGTCGAACCTCACCGACCGGATC
GCGTATCTCGAGAACGGCGACGTCGTCGATATCCAGCTGCACCGCCACTGGATCGTCGACGCGAGCGGGCGGCGCGTCGA
GCGGACGGTGCACACGATCGCCGCGCATGTGGCGGCGGCCGATCTCGGCGGCTATCGCTACTACATGCAAAAGGAGATCT
TCGAGCAGCCGCGCGCGGTCGCCGATACGCTGCTCGACGTCACGTCGATCATGCCCGAGCTGTTCGGCGATCGCGCATGG
CGCGCGCTGAGCGCGGCGGACTCGGTGCTGCTGCTCGCGTGCGGCGGCAGTTATCACGCGGCGCTCACCGCGAAATACTG
GATCGAGAGCATCGCCGGCCTGCCGGCGAACGTCGAGATCGCGAGCGAGTTCCGCTATCGCGACGGCGTGCCGAATCCGA
AGGCGCTCGTCGTCGCGGTGTCGCAAAGCGGCGAGACGGCCGACGTGCTCGGCGCGGTGCACGCGGCGAAGCGGCTCGGC
ATGCCGAACACGCTCGCGATCTGCAACGTGCCGACGAGCGCGCTCGTGCGCGAATGCGCGTCGAGCTTCATCACGCGGGC
CGGCATCGAGGTGGGCGTCGCGTCGACGAAGGCGTTCACGACGCAGCTCGTCGCGCTGTTCCTGTTGACGCTCGCGCTCG
CGCAGGTGCGCGCGCGCTTGTCCGACGAAGACGAGAAGCGGCATCTGCACGCGCTGCGCCACCTGCCCGAGGCGATGAGC
AAGGTGCTCGCGCTCGAGCCGCGGATCATCGCGTGGTCCGAGCGGCTCGCGCGGCGCGAGAACATGCTGTTCCTCGGCCG
CGGGATGCATTATCCGATCGCGCTCGAAGGCGCGCTGAAGATGAAGGAGATCTCGTACATCCACGCGGAGGCGTACGCGG
CGGGCGAATTGAAGCACGGCCCGCTCGCGCTCGTGAGCGACGAGATGCCCGTCATCGCGGTCGCGCCGAACGACCGGCTG
CTCGAGAAGCTGCGCTCGAACATGCACGAGGTGAGCGCGCGCAACGGCCGGCTCTTCGTGTTCGCCGACGTCGATTGCGC
GATCGCGAGCGCGCCGGGCCTCGACGTGATTCGCCTCACCGAATACTACGGGCCGCTCTCGCCGATCCTGCATGCGGTTC
CGATGCAACTGCTCGCGTTCCACGCGGCGCTCACGCGCGGCACCGATATCGACAAGCCGCGCAATCTCGCGAAATCCGTG
ACGGTCGAGTGA

Upstream 100 bases:

>100_bases
AGAAATTTCAGAGAATCGATATTTTTGAAATTAAATTCCATTGTGCCGATTCTACCATCGCGTTCGTCGATCCCGAGCGG
ATCGTTTCACGGAGAGCGAT

Downstream 100 bases:

>100_bases
GGCCGGGCGCGCGCCGCCGCTCGCCGCGCCACGCGAGGGCCGGCGCGCGCGGTTTTCGGGCATCGCGAAATACGCGGCGC
GCGCAATGGGCCGGTGCGCC

Product: glucosamine--fructose-6-phosphate aminotransferase, isomerizing

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MCGIVGAVARRDVVPNLVDGLKRLEYRGYDSCGVVVYQDRRLVRARSVDRVAALQREISARALSGYTGIAHTRWATHGAP
VTANAHPHFSSGVATSGVATPGVATSGAPAASAAASGGTAQADASPEARARIALSHNGIIENYEALRADLERHGYAFASQ
TDSEAIAHLVDHLYDGDLFDAVRRALARLRGSYAIAVMCRDEPHRIVGARDGMPLVVGIGDGEHFLASDAIALSNLTDRI
AYLENGDVVDIQLHRHWIVDASGRRVERTVHTIAAHVAAADLGGYRYYMQKEIFEQPRAVADTLLDVTSIMPELFGDRAW
RALSAADSVLLLACGGSYHAALTAKYWIESIAGLPANVEIASEFRYRDGVPNPKALVVAVSQSGETADVLGAVHAAKRLG
MPNTLAICNVPTSALVRECASSFITRAGIEVGVASTKAFTTQLVALFLLTLALAQVRARLSDEDEKRHLHALRHLPEAMS
KVLALEPRIIAWSERLARRENMLFLGRGMHYPIALEGALKMKEISYIHAEAYAAGELKHGPLALVSDEMPVIAVAPNDRL
LEKLRSNMHEVSARNGRLFVFADVDCAIASAPGLDVIRLTEYYGPLSPILHAVPMQLLAFHAALTRGTDIDKPRNLAKSV
TVE

Sequences:

>Translated_643_residues
MCGIVGAVARRDVVPNLVDGLKRLEYRGYDSCGVVVYQDRRLVRARSVDRVAALQREISARALSGYTGIAHTRWATHGAP
VTANAHPHFSSGVATSGVATPGVATSGAPAASAAASGGTAQADASPEARARIALSHNGIIENYEALRADLERHGYAFASQ
TDSEAIAHLVDHLYDGDLFDAVRRALARLRGSYAIAVMCRDEPHRIVGARDGMPLVVGIGDGEHFLASDAIALSNLTDRI
AYLENGDVVDIQLHRHWIVDASGRRVERTVHTIAAHVAAADLGGYRYYMQKEIFEQPRAVADTLLDVTSIMPELFGDRAW
RALSAADSVLLLACGGSYHAALTAKYWIESIAGLPANVEIASEFRYRDGVPNPKALVVAVSQSGETADVLGAVHAAKRLG
MPNTLAICNVPTSALVRECASSFITRAGIEVGVASTKAFTTQLVALFLLTLALAQVRARLSDEDEKRHLHALRHLPEAMS
KVLALEPRIIAWSERLARRENMLFLGRGMHYPIALEGALKMKEISYIHAEAYAAGELKHGPLALVSDEMPVIAVAPNDRL
LEKLRSNMHEVSARNGRLFVFADVDCAIASAPGLDVIRLTEYYGPLSPILHAVPMQLLAFHAALTRGTDIDKPRNLAKSV
TVE
>Mature_643_residues
MCGIVGAVARRDVVPNLVDGLKRLEYRGYDSCGVVVYQDRRLVRARSVDRVAALQREISARALSGYTGIAHTRWATHGAP
VTANAHPHFSSGVATSGVATPGVATSGAPAASAAASGGTAQADASPEARARIALSHNGIIENYEALRADLERHGYAFASQ
TDSEAIAHLVDHLYDGDLFDAVRRALARLRGSYAIAVMCRDEPHRIVGARDGMPLVVGIGDGEHFLASDAIALSNLTDRI
AYLENGDVVDIQLHRHWIVDASGRRVERTVHTIAAHVAAADLGGYRYYMQKEIFEQPRAVADTLLDVTSIMPELFGDRAW
RALSAADSVLLLACGGSYHAALTAKYWIESIAGLPANVEIASEFRYRDGVPNPKALVVAVSQSGETADVLGAVHAAKRLG
MPNTLAICNVPTSALVRECASSFITRAGIEVGVASTKAFTTQLVALFLLTLALAQVRARLSDEDEKRHLHALRHLPEAMS
KVLALEPRIIAWSERLARRENMLFLGRGMHYPIALEGALKMKEISYIHAEAYAAGELKHGPLALVSDEMPVIAVAPNDRL
LEKLRSNMHEVSARNGRLFVFADVDCAIASAPGLDVIRLTEYYGPLSPILHAVPMQLLAFHAALTRGTDIDKPRNLAKSV
TVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=721, Percent_Identity=33.0097087378641, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI205277386, Length=721, Percent_Identity=33.7031900138696, Blast_Score=362, Evalue=1e-100,
Organism=Escherichia coli, GI1790167, Length=650, Percent_Identity=47.3846153846154, Blast_Score=568, Evalue=1e-163,
Organism=Escherichia coli, GI87082251, Length=321, Percent_Identity=21.8068535825545, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=752, Percent_Identity=29.7872340425532, Blast_Score=299, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17532899, Length=435, Percent_Identity=34.7126436781609, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17532897, Length=435, Percent_Identity=34.7126436781609, Blast_Score=257, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6322745, Length=457, Percent_Identity=35.4485776805252, Blast_Score=256, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=30.5555555555556, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323730, Length=241, Percent_Identity=31.1203319502075, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21357745, Length=729, Percent_Identity=32.7846364883402, Blast_Score=349, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 69267; Mature: 69267

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVARRDVVPNLVDGLKRLEYRGYDSCGVVVYQDRRLVRARSVDRVAALQREISA
CCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
RALSGYTGIAHTRWATHGAPVTANAHPHFSSGVATSGVATPGVATSGAPAASAAASGGTA
HHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
QADASPEARARIALSHNGIIENYEALRADLERHGYAFASQTDSEAIAHLVDHLYDGDLFD
CCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHH
AVRRALARLRGSYAIAVMCRDEPHRIVGARDGMPLVVGIGDGEHFLASDAIALSNLTDRI
HHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEEEEECCCCHHHHHCHHHHHHHHHHH
AYLENGDVVDIQLHRHWIVDASGRRVERTVHTIAAHVAAADLGGYRYYMQKEIFEQPRAV
HEECCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
ADTLLDVTSIMPELFGDRAWRALSAADSVLLLACGGSYHAALTAKYWIESIAGLPANVEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEH
ASEFRYRDGVPNPKALVVAVSQSGETADVLGAVHAAKRLGMPNTLAICNVPTSALVRECA
HHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
SSFITRAGIEVGVASTKAFTTQLVALFLLTLALAQVRARLSDEDEKRHLHALRHLPEAMS
HHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KVLALEPRIIAWSERLARRENMLFLGRGMHYPIALEGALKMKEISYIHAEAYAAGELKHG
HHHHCCCCEEHHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCC
PLALVSDEMPVIAVAPNDRLLEKLRSNMHEVSARNGRLFVFADVDCAIASAPGLDVIRLT
CEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCEEEHH
EYYGPLSPILHAVPMQLLAFHAALTRGTDIDKPRNLAKSVTVE
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVARRDVVPNLVDGLKRLEYRGYDSCGVVVYQDRRLVRARSVDRVAALQREISA
CCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
RALSGYTGIAHTRWATHGAPVTANAHPHFSSGVATSGVATPGVATSGAPAASAAASGGTA
HHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
QADASPEARARIALSHNGIIENYEALRADLERHGYAFASQTDSEAIAHLVDHLYDGDLFD
CCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHH
AVRRALARLRGSYAIAVMCRDEPHRIVGARDGMPLVVGIGDGEHFLASDAIALSNLTDRI
HHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEEEEECCCCHHHHHCHHHHHHHHHHH
AYLENGDVVDIQLHRHWIVDASGRRVERTVHTIAAHVAAADLGGYRYYMQKEIFEQPRAV
HEECCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
ADTLLDVTSIMPELFGDRAWRALSAADSVLLLACGGSYHAALTAKYWIESIAGLPANVEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEH
ASEFRYRDGVPNPKALVVAVSQSGETADVLGAVHAAKRLGMPNTLAICNVPTSALVRECA
HHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
SSFITRAGIEVGVASTKAFTTQLVALFLLTLALAQVRARLSDEDEKRHLHALRHLPEAMS
HHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KVLALEPRIIAWSERLARRENMLFLGRGMHYPIALEGALKMKEISYIHAEAYAAGELKHG
HHHHCCCCEEHHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCC
PLALVSDEMPVIAVAPNDRLLEKLRSNMHEVSARNGRLFVFADVDCAIASAPGLDVIRLT
CEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCEEEHH
EYYGPLSPILHAVPMQLLAFHAALTRGTDIDKPRNLAKSVTVE
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]