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The map label for this gene is pabB [H]

Identifier: 126454445

GI number: 126454445

Start: 3225453

End: 3227462

Strand: Reverse

Name: pabB [H]

Synonym: BURPS1106A_3308

Alternate gene names: 126454445

Gene position: 3227462-3225453 (Counterclockwise)

Preceding gene: 126452366

Following gene: 126453743

Centisome position: 80.92

GC content: 72.49

Gene sequence:

>2010_bases
ATGACTGACGAAGCGGGCGCGGTTTTCGCGCTCTTCGACGATTGCGACTCGACCGCGGCGGCGCGCTCGAGTCGTTTGTA
TTCGGGCTTCTCGCACGAGCGGGCCTGCGCCGATCCGGCCGGCCTCGACGCGGTGTGCGCGGCCGTCGCCGACGACGCGC
GGCGCGGGCTGCACGCCGTCGTGCTCGGCGACTACGAGTTCGGGCGCGACCTGCAGCTCGGCAAGCGCGGCGGCGGCGCG
TTGCGGTTCCTGCTGTTCGCCGAATGCAGGATGCTCTCGCGCGAGGAGGCCGACGCGTGGCTCGCGTCGCGCGACGGCGG
CTCGGCCGAGCCGTCGGCGGCGGGCGTCGCGCACGTGACGAAGAGCGTCGCGCGCGACGCGTTCGACGCGGCGATCGCCG
CCGTGCACGATGCGCTGCGCGCGGGCGATTCGTATCAGATCAACTACACGTACCGGCTGCATTTCGATGCGTTCGGCGCG
CCGCTCGCGCTGTATCGCCGCCTGCGGGCGCGCCAGCCGGTGCGCTACGGCGCGCTCGTCGCGCTGCCGGGCGGCGCGTG
GATCGTGTCGTGCTCGCCCGAGCTGTTCGTCGAGAAGACGGGCGCGTTGCTGCGCGCGCGGCCGATGAAAGGCACCGCGC
CTCGCTCGGACGATCCGCGCGAGGATGCGGCCGCCGCGCGCTTTCTCGCGAACGATGCGAAGAATCGCGCCGAGAACGTG
ATGATCGTCGATCTGCTGCGCAACGATCTCGCGCGCATCGCGCGCACCGGATCGGTGACGGTGCCGGCGTTGTTCTCGGT
CGAGCCGTATGCGTCGGTGTGGCAGATGACGTCGACGGTCGAGGCGGGCATCGTCGAAGGCGCGACGTTCGCCGACGTGC
TGCGCGCGCTCTTTCCGTGCGGCTCGATCACGGGCGCGCCGAAGCACAGGACGATGCAACTGATCGATGCGCTCGAGACG
ACGCCGCGCGGGCTCTATACGGGCGCGATCGGCTGGCTCGATGCGGAGGAGGCGCGTGCGGACGGCGCCGAGCCTGCCGC
CGGCGCGTTCGCGCCGGCGCGTGCGGCGAGCCCGGCCGCAGGCACGGCGTCGGATGGTGCGTGCGCGGGCGAAATCGCGT
CGAAGCAGGCGTCGAAGCGTGCCGGCGCGACAAGCCCGGCCGGCGCGTGCGGCGATTTCTGCCTGTCGGTCGCGATCCGC
ACGCTGACGCTCGACGCGCCGTCGGCCGGCGGCGAGCGGCGCGGCACGATGGGCGTCGGCGCGGGCATCGTGCTCGACAG
CGTTGCCGCCGACGAATACGCGGAGTGCGAATTGAAGGCGCGTTTCCTGACCGACGCCGAGCCCGGCTTCCAGTTGTTCG
AGACGATGCTCGCCACGCGTGACGCCGGCGTGCGCCATCTCGACCGCCATGTCGCGCGGCTGCGCGCGAGTGCCGACGCG
CTCGGCTTCGCGTTCGACGAAGCGGCGGCCAGGCAGCGCATCGGCGCGCGCTGCGTGCAGCTCGGCGACGGCGAGCATCG
CTTGCGCGTCGCGCTCGCGAAGGACGGCGTGCTCGACATCGTGGCCGCGCCGCTCGCGCCGCTCGCGGGCGCCGCGGTGG
CCGTGTTGCTCGCGCCCGAGCACGGGTTCGCGCCGATGCGCTCGGGCGACTTCCTGCTCGCGCACAAGACGACGCGCCGC
GCCGATTACGATCGCGCGTGGAAAGCCGCGCAGGCGTGCGGTGCGTTCGACATGCTGTTCTTCAACGAACGCGGCGAATT
GACCGAAGGCGGGCGCACGAGCGTATTCGTGAAGCTGGCCGGGCGCTGGTTCACGCCGCCGCTGTCGTCGGGCGTGTTGC
CGGGCGTGATGCGCGGCGCGCTGCTCGACGATCCGGCATGGCAGGCGTCCGAGCGTGTAATGACGCTGGACGACGTGCTG
CGCGCCGACGCGCTGATGCTGACGAACGCATTGCGCGGCGCGATGCCCGCGCAACTCGTGCGGGCCGCCGGCGCGGCGGC
ACCGCGATAG

Upstream 100 bases:

>100_bases
AGGCGGCCCGCGTCACAGCCCGCAGAGCAAGAGCTGGTTCGACCGCGTGAAGAGCTTCTTCGAGTGACGCCCGGCGTGCG
GCCCGCAGGTGAGAGGCAGG

Downstream 100 bases:

>100_bases
GCGCGCGAAGAGCGGCCGGGCGGCCGGGCGGTCGCACGCATCGCCCTCGCGCTTCGGCTCGCAAAAAGCGGCATCCCGCA
CGTGCGGGATGCCGCTTTTT

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYEFGRDLQLGKRGGGA
LRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGA
PLALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALET
TPRGLYTGAIGWLDAEEARADGAEPAAGAFAPARAASPAAGTASDGACAGEIASKQASKRAGATSPAGACGDFCLSVAIR
TLTLDAPSAGGERRGTMGVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADA
LGFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSGDFLLAHKTTRR
ADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVL
RADALMLTNALRGAMPAQLVRAAGAAAPR

Sequences:

>Translated_669_residues
MTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYEFGRDLQLGKRGGGA
LRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGA
PLALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALET
TPRGLYTGAIGWLDAEEARADGAEPAAGAFAPARAASPAAGTASDGACAGEIASKQASKRAGATSPAGACGDFCLSVAIR
TLTLDAPSAGGERRGTMGVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADA
LGFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSGDFLLAHKTTRR
ADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVL
RADALMLTNALRGAMPAQLVRAAGAAAPR
>Mature_668_residues
TDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYEFGRDLQLGKRGGGAL
RFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGAP
LALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENVM
IVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALETT
PRGLYTGAIGWLDAEEARADGAEPAAGAFAPARAASPAAGTASDGACAGEIASKQASKRAGATSPAGACGDFCLSVAIRT
LTLDAPSAGGERRGTMGVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADAL
GFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSGDFLLAHKTTRRA
DYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLR
ADALMLTNALRGAMPAQLVRAAGAAAPR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=246, Percent_Identity=40.650406504065, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1787518, Length=219, Percent_Identity=31.9634703196347, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786809, Length=173, Percent_Identity=27.7456647398844, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=213, Percent_Identity=31.924882629108, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324361, Length=232, Percent_Identity=30.1724137931034, Blast_Score=94, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 70335; Mature: 70204

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAV
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEE
VLGDYEFGRDLQLGKRGGGALRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVT
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGAPLALYRRLRARQPVRYGALV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEE
ALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
EECCCCEEEECCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCE
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPC
EEHHHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GSITGAPKHRTMQLIDALETTPRGLYTGAIGWLDAEEARADGAEPAAGAFAPARAASPAA
CCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
GTASDGACAGEIASKQASKRAGATSPAGACGDFCLSVAIRTLTLDAPSAGGERRGTMGVG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCC
AGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADA
CHHHHHHHHCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
HGFAPMRSGDFLLAHKTTRRADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLA
CCCCCCCCCCEEEEECCHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEEC
GRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLRADALMLTNALRGAMPAQLV
CCCCCCCCCCCCCHHHHHCCCCCCCCCHHHCCEECHHHHHHHHHHHHHHHHHCCHHHHHH
RAAGAAAPR
HHHCCCCCC
>Mature Secondary Structure 
TDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAV
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEE
VLGDYEFGRDLQLGKRGGGALRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVT
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGAPLALYRRLRARQPVRYGALV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEE
ALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
EECCCCEEEECCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCE
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPC
EEHHHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GSITGAPKHRTMQLIDALETTPRGLYTGAIGWLDAEEARADGAEPAAGAFAPARAASPAA
CCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
GTASDGACAGEIASKQASKRAGATSPAGACGDFCLSVAIRTLTLDAPSAGGERRGTMGVG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCC
AGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADA
CHHHHHHHHCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
HGFAPMRSGDFLLAHKTTRRADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLA
CCCCCCCCCCEEEEECCHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEEC
GRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLRADALMLTNALRGAMPAQLV
CCCCCCCCCCCCCHHHHHCCCCCCCCCHHHCCEECHHHHHHHHHHHHHHHHHCCHHHHHH
RAAGAAAPR
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]