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The map label for this gene is dapL [H]

Identifier: 126454437

GI number: 126454437

Start: 2461387

End: 2462619

Strand: Direct

Name: dapL [H]

Synonym: BURPS1106A_2504

Alternate gene names: 126454437

Gene position: 2461387-2462619 (Clockwise)

Preceding gene: 126451482

Following gene: 126454271

Centisome position: 61.71

GC content: 70.32

Gene sequence:

>1233_bases
GTGAATCCTCGCCTCGACACGCTCCAGCCCTATCCGTTCGAAAAGCTCCGCGCGCTCTTTGCCGGCGTGACGCCAAGCAC
GCCCCTGCCGCCGATCAGCTTCGGCATCGGCGAGCCGAAGCACGCGACGCCCGCGCTGATCCGCGACGCCGCGGCCGCCG
CGCTCGACGGCCTCGCGTCGTATCCGGCGACGGCGGGCACCGACGCGCTTCGCGATACCGTCGCGCGCTGGCTCGAGCGG
CGCTACGGGCTGCCCGCGATCGACGCGACGACGCAGGTGCTCGCCGCGTCGGGCTCGCGCGAGGCGCTCTTCTCGCTCGC
GCAGGCGGTGATCGATTCGAGCCCGCGCGAAAACGGCGCGACGCAGGACGGCGAAAGGCCGATCGTACTCTGTCCGAATC
CTTTCTATCAAATCTACGAAGGCGCGGCGCTCCTCGCGGGCGCCGCGCCGTACTTCGTCAACAGCGATCCGGCGCGCAAC
TTCGCGCCCGACTATTCGAGCGTGCCGGCCGACGTCTGGGCGCGCACGCAGCTCGTCTACGTGTGCTCGCCGGGCAACCC
GACGGGCGCCGTGCTCACGCTCGACGACTGGCGCGAGCTGTTCGCGCTGTCCGACGAACACGGCTTCGTGATCGCGTCGG
ACGAATGCTATTCGGAGATCTATTTCGACGAGACGAAGCCGCCGCTGGGCGGCCTCGAGGCGGCGCACCGGCTCGGCCGC
GACTTCACGCGCCTCGTGATGCTCTCGAGCCTGTCCAAGCGTTCGAACGTGCCGGGCATGCGTTCGGGCTTCGTCGCGGG
CGACGCGGCGCTCCTCAAGCGCTTCCTGCTGTACCGCACCTACCACGGCGCGGCGCTGTCGCCCGTCTGGCAGAAGGCGA
GCGTCGCCGCCTGGGGCGACGAGGCGCACGTGCGCGAGAACCGCGCGCTCTACGCGCAGAAATTCGCGACCGTCACGCCG
ATGCTCGCCGAGGTCCTCGACGTGCGTCTGCCCGATGCCGCGTTCTACCTGTGGGCGAACGTCGCGCGAACCGGCCTGTC
GGATACCGAGTTCGCCCGGCGCCTCTACGCCGACTATAATGTGACGGTCCTGCCCGGCTCGTATCTCGCCCGCGACGCGC
ACGGCGCGAATCCCGGCCGCGACTTCGTCCGGATCGCGCTCGTCGCCGGCACGGCCGAATGCGTCGAAGGCGCGCAGCGC
ATCGTCGATTTCTGCCGCGGCCTCGCCCGCTGA

Upstream 100 bases:

>100_bases
GCCCGCGCAAGGCGGCGCCAGCCGCGCCGCCGCCTTGCGCCGCTTCGCTTAAACCGGCCCGTCCGATCGGCCACCTACCG
GCTCCGTGAGCCCCACGCCC

Downstream 100 bases:

>100_bases
ACGCGCGCCGAAACGCCCCGATTCATTCATCATCCACGTCCAGCATAGCCACGAACATGTCGCAACAACTTCAGCAAATC
ATCGATAACACCTGGGAAAA

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNPRLDTLQPYPFEKLRALFAGVTPSTPLPPISFGIGEPKHATPALIRDAAAAALDGLASYPATAGTDALRDTVARWLER
RYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRENGATQDGERPIVLCPNPFYQIYEGAALLAGAAPYFVNSDPARN
FAPDYSSVPADVWARTQLVYVCSPGNPTGAVLTLDDWRELFALSDEHGFVIASDECYSEIYFDETKPPLGGLEAAHRLGR
DFTRLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGDEAHVRENRALYAQKFATVTP
MLAEVLDVRLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAGTAECVEGAQR
IVDFCRGLAR

Sequences:

>Translated_410_residues
MNPRLDTLQPYPFEKLRALFAGVTPSTPLPPISFGIGEPKHATPALIRDAAAAALDGLASYPATAGTDALRDTVARWLER
RYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRENGATQDGERPIVLCPNPFYQIYEGAALLAGAAPYFVNSDPARN
FAPDYSSVPADVWARTQLVYVCSPGNPTGAVLTLDDWRELFALSDEHGFVIASDECYSEIYFDETKPPLGGLEAAHRLGR
DFTRLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGDEAHVRENRALYAQKFATVTP
MLAEVLDVRLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAGTAECVEGAQR
IVDFCRGLAR
>Mature_410_residues
MNPRLDTLQPYPFEKLRALFAGVTPSTPLPPISFGIGEPKHATPALIRDAAAAALDGLASYPATAGTDALRDTVARWLER
RYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRENGATQDGERPIVLCPNPFYQIYEGAALLAGAAPYFVNSDPARN
FAPDYSSVPADVWARTQLVYVCSPGNPTGAVLTLDDWRELFALSDEHGFVIASDECYSEIYFDETKPPLGGLEAAHRLGR
DFTRLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGDEAHVRENRALYAQKFATVTP
MLAEVLDVRLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAGTAECVEGAQR
IVDFCRGLAR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=280, Percent_Identity=25, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI169881279, Length=280, Percent_Identity=25, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI56713256, Length=410, Percent_Identity=21.7073170731707, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI56713254, Length=410, Percent_Identity=21.7073170731707, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788722, Length=412, Percent_Identity=26.6990291262136, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786816, Length=347, Percent_Identity=24.7838616714697, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788627, Length=236, Percent_Identity=22.4576271186441, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859735, Length=413, Percent_Identity=25.4237288135593, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44434; Mature: 44434

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRLDTLQPYPFEKLRALFAGVTPSTPLPPISFGIGEPKHATPALIRDAAAAALDGLAS
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YPATAGTDALRDTVARWLERRYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRENGA
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
TQDGERPIVLCPNPFYQIYEGAALLAGAAPYFVNSDPARNFAPDYSSVPADVWARTQLVY
CCCCCCCEEECCCHHHHHHCCHHHHHCCCCCEECCCCCCCCCCCCCCCCHHHHCCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDEHGFVIASDECYSEIYFDETKPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCCCCHHHHHHHHHH
DFTRLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGD
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCHHHHHCCCEECCC
EAHVRENRALYAQKFATVTPMLAEVLDVRLPDAAFYLWANVARTGLSDTEFARRLYADYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCC
VTVLPGSYLARDAHGANPGRDFVRIALVAGTAECVEGAQRIVDFCRGLAR
EEEECCHHHHCCCCCCCCCHHHEEEHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPRLDTLQPYPFEKLRALFAGVTPSTPLPPISFGIGEPKHATPALIRDAAAAALDGLAS
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YPATAGTDALRDTVARWLERRYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRENGA
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
TQDGERPIVLCPNPFYQIYEGAALLAGAAPYFVNSDPARNFAPDYSSVPADVWARTQLVY
CCCCCCCEEECCCHHHHHHCCHHHHHCCCCCEECCCCCCCCCCCCCCCCHHHHCCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDEHGFVIASDECYSEIYFDETKPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCCCCHHHHHHHHHH
DFTRLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGD
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCHHHHHCCCEECCC
EAHVRENRALYAQKFATVTPMLAEVLDVRLPDAAFYLWANVARTGLSDTEFARRLYADYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCC
VTVLPGSYLARDAHGANPGRDFVRIALVAGTAECVEGAQRIVDFCRGLAR
EEEECCHHHHCCCCCCCCCHHHEEEHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA