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The map label for this gene is comL [H]

Identifier: 126454430

GI number: 126454430

Start: 2195198

End: 2196022

Strand: Direct

Name: comL [H]

Synonym: BURPS1106A_2206

Alternate gene names: 126454430

Gene position: 2195198-2196022 (Clockwise)

Preceding gene: 126452316

Following gene: 126452035

Centisome position: 55.04

GC content: 64.61

Gene sequence:

>825_bases
ATGATGCATTCGACCAAACGCGTCGCAAAACCTGCGGCCGCCTGGGCCGCGCTGGCGGCGGCCGCGGCGCTCGTCGCGGG
TTGCCACGGCTTGCCGCAGAAGAGCGATGAGACGGCAACCTGGTCGAACAACAAATTATACTCAGAGGCTCAGGATGCAT
TGACGGGCGGCGACTGGGGCAAGTGCGCGAAGTACTTCGAGGCGCTGCAAGGCCGCGATCCGTTCGGCCACTTCGCGCAA
CAGGCGCAGATCAACGTCGCCTACTGCAACTGGAAGGACAACGAAACGGCCGCCGCCGATCAGGCGGTCGACCGCTTCAT
CCAGTTGCACCCGGATCACCCGGACGTCGCGTATGCGTACTACCTGAAGGGGATGATCCACTTCAACGACGACCTGGGCC
TGTTCGGCCGCTTCTCCGGCCAGGACATGAGCGAGCGCGATCCGCAGGCGCTGCGCGAATCGTACGATGCGTTCAAGGTC
GTCGTCGACCGCTATCCGAAGAGCAAGTACGCGCCCGACGCGGCCGCGCGCATGCGCTACATCGTCAACGCGCTCGCGTC
GCACGAAGTGCACGCGGCCGACTACTACTACCGGCGCGGCGCCTATGTCGCGGCGATCAACCGCGCGCAGCTTGCGATCA
AGGAATACAAGAACGCGCCGGCGATCGAGGACGCGCTGCACATCATGATGCTGTCGTACGCGAAGCTGAATCAGCCGCAG
CTCGCCGACGACACGAAGCGCGTGCTCGCCTCGACGTTCCCGGACAGCCCGTACGTGACCGGCCACGCGCGGCCGGGCTC
GAAGAAATCGTGGTGGCAATTCTGA

Upstream 100 bases:

>100_bases
CGGTTTGACTTGCCCGCACGGGCATTCAACGAACTTGAACGGGTCATTTAGACTGGGTCACTTGAGACTTGAAGCTAGGA
CAATGCGAGCCCTTTTCACC

Downstream 100 bases:

>100_bases
GCTGAGCGTCGCGATTCGCGCTGCGTGCGCGACCGATGGTGCGCGATCGGCGCATCGACAAAGAAACCCGGCCTGTCGAG
CCGGGTTTTTCTTTTCGCGC

Product: putative competence lipoprotein ComL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWGKCAKYFEALQGRDPFGHFAQ
QAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRESYDAFKV
VVDRYPKSKYAPDAAARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYAKLNQPQ
LADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF

Sequences:

>Translated_274_residues
MMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWGKCAKYFEALQGRDPFGHFAQ
QAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRESYDAFKV
VVDRYPKSKYAPDAAARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYAKLNQPQ
LADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF
>Mature_274_residues
MMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWGKCAKYFEALQGRDPFGHFAQ
QAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRESYDAFKV
VVDRYPKSKYAPDAAARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYAKLNQPQ
LADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF

Specific function: Required for efficient transformation of Neisseria gonorrhoeae by species-related DNA [H]

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=237, Percent_Identity=35.0210970464135, Blast_Score=157, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689
- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30592; Mature: 30592

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
KCAKYFEALQGRDPFGHFAQQAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAY
HHHHHHHHHCCCCCHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
YLKGMIHFNDDLGLFGRFSGQDMSERDPQALRESYDAFKVVVDRYPKSKYAPDAAARMRY
HHHHHEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYAKLNQPQ
HHHHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
LADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF
CCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure
MMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
KCAKYFEALQGRDPFGHFAQQAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAY
HHHHHHHHHCCCCCHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
YLKGMIHFNDDLGLFGRFSGQDMSERDPQALRESYDAFKVVVDRYPKSKYAPDAAARMRY
HHHHHEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYAKLNQPQ
HHHHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
LADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF
CCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8830266 [H]