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The map label for this gene is blh [H]

Identifier: 126454369

GI number: 126454369

Start: 2157352

End: 2158254

Strand: Direct

Name: blh [H]

Synonym: BURPS1106A_2172

Alternate gene names: 126454369

Gene position: 2157352-2158254 (Clockwise)

Preceding gene: 126453059

Following gene: 126454829

Centisome position: 54.09

GC content: 69.55

Gene sequence:

>903_bases
GTGACAACAGCGTCCACGATGACGGTCGAAGGCTTTTTCGACCCGGCGACATGCACGATCAGCTATTTGCTGTTCGATTC
CGGCAGCGGCGAATGCGCGCTGATCGACAGCGTGCTCGACTACGACCCGAAATCCGGCCGCACGCGCACCGCGAGCGCGG
ACCAGTTGATCGCGCGCGTCGCGGCGCTCGGCGCGCGCGTGCGCTGGCTGCTCGAGACGCACGTGCACGCCGACCATCTG
TCGGCCGCGCCGTACCTGAAAACGCGGGTCGGCGGCGAGATCGCGATCGGCCGCCACGTGACGCGCGTGCAGGACGTGTT
CGGCAAGCTGTTCAACGCAGGCCCCGCGTTCGCGCACGACGGCAGCCAGTTCGACCGCCTGCTCGACGACGGCGACACGC
TCGCGCTCGGCGCGCTCTCGATCCGCGCGATGCATACGCCGGGCCACACGCCGGCGTGCATGACCTACGTCGTCACCGAA
GCGCATGCGGCGCACGACGCGCGCGACGCGGCCGCGTTCGTCGGCGATACGCTGTTCATGCCCGACTACGGCACCGCGCG
CTGCGACTTCCCCGGCGGCGACGCGCGCTCGCTGTACCGGTCGATCCGCAAGGTGCTGAGCCTGCCGCCCGCGACGCGCC
TGTACATGTGCCACGACTATCAGCCGAACGGCCGCGCGATCCAGTACGCGAGCACCGTCGCCGACGAGTTGCGCGAGAAC
GTGCACATCCGCGAAGGCGTCACCGAGGACGATTTCGTCGCGATGCGCACCGCGCGCGACGCGACGCTCGACATGCCGGT
GCTGATGCTGCCCTCGGTGCAGGTCAACATGCGCGCGGGCCGCCTGCCCGAGCCCGAGGACAACGGCGTGCGCTACCTGA
AGATCCCGCTCGACGCGATCTGA

Upstream 100 bases:

>100_bases
AATCAAGTACCTGTGCTCGCCGATCGGCAATGCTGTCAACTTGGCACGGTTCTTGTTCGAATGAACGCCATCTCGACGAA
TGGGCTCCAGGAGAAACCTC

Downstream 100 bases:

>100_bases
GCCCGCGGCCCGCCTTCCCCAACGACGCACGACATACGACCACGCCCATCATGGAAATCCGCAAGCTGACCGACACGCTA
TCGGTCTCCCCCCAACTCGT

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLETHVHADHL
SAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTE
AHAAHDARDAAAFVGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTVADELREN
VHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI

Sequences:

>Translated_300_residues
MTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLETHVHADHL
SAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTE
AHAAHDARDAAAFVGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTVADELREN
VHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI
>Mature_299_residues
TTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLETHVHADHLS
AAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEA
HAAHDARDAAAFVGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTVADELRENV
HIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=279, Percent_Identity=30.1075268817204, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17538952, Length=266, Percent_Identity=29.6992481203008, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI221330176, Length=277, Percent_Identity=29.2418772563177, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32684; Mature: 32553

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARV
CCCCCEEEEECCCCCHHEEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCHHHHHHHH
AALGARVRWLLETHVHADHLSAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHD
HHHHHHHHHHHHHHCCHHHHCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCCCCC
GSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEAHAAHDARDAAAFVGDTLFM
CHHHHHHHCCCCEEEEEEEEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHHHCCEEEC
PDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTVADELREN
CCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHC
VHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI
CCHHCCCCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
TTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARV
CCCCEEEEECCCCCHHEEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCHHHHHHHH
AALGARVRWLLETHVHADHLSAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHD
HHHHHHHHHHHHHHCCHHHHCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCCCCC
GSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEAHAAHDARDAAAFVGDTLFM
CHHHHHHHCCCCEEEEEEEEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHHHCCEEEC
PDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTVADELREN
CCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHC
VHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI
CCHHCCCCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]