Click here to switch to the map view.

The map label for this gene is hexR [H]

Identifier: 126454355

GI number: 126454355

Start: 647181

End: 648074

Strand: Direct

Name: hexR [H]

Synonym: BURPS1106A_0673

Alternate gene names: 126454355

Gene position: 647181-648074 (Clockwise)

Preceding gene: 126453518

Following gene: 126454470

Centisome position: 16.23

GC content: 71.92

Gene sequence:

>894_bases
ATGACGCCATTCGCCGAGCAGCCCGCCTTCGACATCGTCGCCCGCATCGCCGAGTGCGCGCCCGAGTTGCGCGATGCCGA
GCGCAAGGTGGCGGCGCTGATCCTCGGCGATCTCGCGCAGGCCGCGCACGCGAGCATCGGCGCGCTCGCCGCGCGGGCGG
ACGTGAGCGTCGCCACCGTCACGCGCTTCGCGAAGGCGGTGGGCTGCCGCGACGTGCGCGAGCTCAAGCTGCGGCTCGCG
CAGGCGGCCGCGGTCGGCCAGCGCTTTCTGGCGCCGGCCGCCGCCGACGCTCAGCGCGACGAGACGCCCGTTTCGCGCGT
GTACGAAGACGTGCGGATCGCGCTCGAACACAATCACCGTTTGCTGCGCCAGACGTCGTTCGACGCGGCCGCCGCCGCGC
TCGCCGCGGCGAACATGATCTACGTGTACGGGCAGGGCGGCGGCTCGACCGCGCTCGCCGACGAACTGCGCTTTCGCCTC
GTGCGTTTCGGCCGGCCGGTCGCGAGCTACCAGGACGCGCTGCTGCAGCGGATGGTCGCGGCCACCGCGGCGCCCGGCTG
CGTCGTCGTCGCGCTGTCGGTGTCCGGGCGCGTTCCGGAGCAGCTCGAGAGCTGCGCGCTCGCGAAGCGCTACGGCGCGA
CGCTCGTCGCGCTGACCGCGCCCGCTTCGCCGCTCGCGCAACTCGCCGATCACCTGATTCCCGTCGTCGCGTTCGAAACC
GATTTCATCTTCAAGCCGTCGACATCGCGCTATGCGATGCTGATGGCGCTCGACGTGCTCGTCACCGAAGTCGCGCTGCG
CCTGGGCGACGATTGCCGCGAGCTGCTGCGCCGGATGAAGCACGCGCTCGACATGCACCGCGGCGGCGGCGAGCGCCAAC
CGTTAGGAGACTGA

Upstream 100 bases:

>100_bases
GTTGACTTCGCGATAGTACAGAAAGTAGCATCGCAGCGGTGATGTTATTTATTAACATGCCGGTGCGCGCCGGCTGTCCC
CGTCAATCGATCGCCGCCTC

Downstream 100 bases:

>100_bases
CATGCACTCGCATCCCGAAGTGGCCGATACGCTGATCGTCGGCGCGCAGTTGTACGACGGCACGGGCGCGCCGAGCGTCG
AGCGCGACGTCGCGATACGC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTPFAEQPAFDIVARIAECAPELRDAERKVAALILGDLAQAAHASIGALAARADVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLAPAAADAQRDETPVSRVYEDVRIALEHNHRLLRQTSFDAAAAALAAANMIYVYGQGGGSTALADELRFRL
VRFGRPVASYQDALLQRMVAATAAPGCVVVALSVSGRVPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
DFIFKPSTSRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGERQPLGD

Sequences:

>Translated_297_residues
MTPFAEQPAFDIVARIAECAPELRDAERKVAALILGDLAQAAHASIGALAARADVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLAPAAADAQRDETPVSRVYEDVRIALEHNHRLLRQTSFDAAAAALAAANMIYVYGQGGGSTALADELRFRL
VRFGRPVASYQDALLQRMVAATAAPGCVVVALSVSGRVPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
DFIFKPSTSRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGERQPLGD
>Mature_296_residues
TPFAEQPAFDIVARIAECAPELRDAERKVAALILGDLAQAAHASIGALAARADVSVATVTRFAKAVGCRDVRELKLRLAQ
AAAVGQRFLAPAAADAQRDETPVSRVYEDVRIALEHNHRLLRQTSFDAAAAALAAANMIYVYGQGGGSTALADELRFRLV
RFGRPVASYQDALLQRMVAATAAPGCVVVALSVSGRVPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFETD
FIFKPSTSRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGERQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=288, Percent_Identity=32.9861111111111, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788767, Length=283, Percent_Identity=24.3816254416961, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082369, Length=212, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31770; Mature: 31639

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPFAEQPAFDIVARIAECAPELRDAERKVAALILGDLAQAAHASIGALAARADVSVATV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLAPAAADAQRDETPVSRVYEDVRIALEHNHR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLRQTSFDAAAAALAAANMIYVYGQGGGSTALADELRFRLVRFGRPVASYQDALLQRMVA
HHHHHCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ATAAPGCVVVALSVSGRVPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHEECC
DFIFKPSTSRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGERQPLGD
CEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TPFAEQPAFDIVARIAECAPELRDAERKVAALILGDLAQAAHASIGALAARADVSVATV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLAPAAADAQRDETPVSRVYEDVRIALEHNHR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLRQTSFDAAAAALAAANMIYVYGQGGGSTALADELRFRLVRFGRPVASYQDALLQRMVA
HHHHHCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ATAAPGCVVVALSVSGRVPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHEECC
DFIFKPSTSRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGERQPLGD
CEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]