| Definition | Burkholderia pseudomallei 1106a chromosome I, complete genome. |
|---|---|
| Accession | NC_009076 |
| Length | 3,988,455 |
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The map label for this gene is aceE [H]
Identifier: 126454194
GI number: 126454194
Start: 2628121
End: 2630793
Strand: Reverse
Name: aceE [H]
Synonym: BURPS1106A_2667
Alternate gene names: 126454194
Gene position: 2630793-2628121 (Counterclockwise)
Preceding gene: 126454969
Following gene: 126452707
Centisome position: 65.96
GC content: 65.58
Gene sequence:
>2673_bases ATGAAGTACGTCGCAGCCGAACGCGACGACGACGCGCAGGAAACCGTCGAATGGCTCGAAGCGCTCGACGGCGTGATTTC GTCGGTCGGCCCCGGCCGCGCGCACTACCTGATCGAAAAGCAGATCGAATTCGCGCGCATGCACGGCGAGCACTTGCCGT TCTCCGCGAACACCCCGTACATCAACACGATTCCCGTCGAAGCCCAGGCGAAGATTCCGGGCGACCAGGACATCGAGCAC CGGATCCGCTCGTACACGCGCTGGAACGCGATCGCGATGGTGCTGCGCGCGGGCAAGCACACGAACGTCGGCGGCCACAT CGCGTCGTTCGCTTCGGCCGCGACGCTCTATGACGTCGGCTACAACCACTTCTGGCACGCGCCGTCCGCCGAGCACGGCG GCGATCTCGTGTTCGTGCAGGGCCATTCGTCGCCCGGCATTTACTCGCGCGCGTTCCTGCTCGGCCGCCTGACGGAAGAT CAGCTCGACAACTTCCGCCAGGAAGTGGGCGGCAACGGCATCTCGTCGTATCCGCACCCGTGGCTGATGCCGGATTTCTG GCAGTTCCCGACCGTGTCGATGGGCCTCGGTCCCATCATGGCGATCTATCAGGCGCGCTTCATGAAGTACCTGCAGGCGC GCGGGATCGTGAAGACGGAAGGCCGCAAGGTCTGGGCGTTCCTCGGCGACGGCGAGACCGACGAGCCGGAATCGCTCGGC GCGATCGGCATGGCGAGCCGCGAGAAGCTCGATAACCTCGTGTTCGTGATCAACTGCAACCTGCAGCGTCTCGACGGCCC GGTGCGCGGCAACGGCAAGATCATCCAGGAGCTCGAATCGGAGTTCCGCGGCGCCGGCTGGAACGTGATCAAGGTGATCT GGGGCAGCCGCTGGGATGCGCTGTTCGCGCGCGACAAGACGGGCGCGCTGATGCGCCGGATGATGGAAGCCGTCGACGGC GAGTATCAGACGTACAAGTCGGAGTCGGGCGCGTACGTGCGCGAGCACTTCTTCAACACGCCGGAGCTGAAGGCGCTCGT CGCCGACTGGTCCGACGACGACATCTGGAACCTGAACCGCGGCGGCCACGATCCGCACAAGATCTACGCGGCGTTCCACG AGGCGAGCAATTCGAAGGGCGCGCCGACGGTGATCCTTGCGAAGACGATCAAGGGCTACGGGATGGGCGAAGCCGGCCAG GCGATGAACATCACGCACCAGCAGAAGAAGTTGCCCGTCGAGCAACTGAAGAAGTTCCGCGACCAGTTCCGCCTGCCGAT CGCCGACGACGTGATCGCCGACGTGCCGTACCTGAAGTTCGACGAAGGCTCGAAGGAACTCGAGTACATGCGCGCGCACC GCCAGGCGCTCGGCGGCTATCTGCCGCAGCGCCGCCAGAAGGCGCAATCGCTGCCGGTGCCGGCGCTCGACGCGTTCGAG CCGCTGCTCAAGGGCACGGGCGAAGGCCGCGAGATCTCGACGACGATGGCGTTCGTGCGGATCCTGAACATCCTGCTGAA GGACAAGGCGCTCGGCAAGCGCGTCGTGCCGATCGTGCCGGACGAATCGCGCACGTTCGGCATGGAGGGCCTGTTCCGCC AGATCGGCATCTGGAACCAGGAAGGCCAGAAGTATGTGCCGGAAGATTCCGATCAACTGATGTTCTACAAGGAATCGGAA ACCGGCCAGATCCTGCAGGAAGGCATCAACGAAGCGGGCGGCATGTGCGACTGGATCGCGGCGGCGACGTCGTACTCGAC GCACGGCGAGATCATGGTGCCGTTCTATATCTTCTATTCGATGTTCGGCTTCCAGCGCATCGGCGATCTCGCGTGGGCGG CGGGCGACATGCGCTCGCGCGGTTTCCTGCTCGGCGGCACCGCGGGCCGCACGACGCTCAACGGCGAAGGCCTGCAGCAC GAAGACGGCCACTCGCTGATGTGGGCGGCTTCGGTGCCGAACTGCGTGAGCTACGATCCGACGTTCGGCTACGAGCTCGC CGTCATCGTGCAGGACGGCCTGCGCCGGATGGTGCAGGAGCAGGAGGACGTCTATTACTACGTGACGGTGATGAACGAGA ACTACGAGCACCCGGCGATTCCGCAGGGCGAGCACGTGGCGGCCGACATCATCAAGGGCATGTACGCGTTCAGGAAGGCC GACGCCGACAAGAAGGCGCCGCGCGTGCAACTGCTCGGCGCGGGCACGATCTTCAACGAAGTGATCGCCGCGGCGGACCT GCTGAAGAACGACTGGGGCGTCGCCGCCGATCTCTGGAGCGTGCCGAGCTTCACCGAGCTCGCGCGCGAAGGCCATGACG TCGAGCGCTGGAACCTGCTGCATCCGGCCGAGGCGCGCCGCCTGTCGCACGTGCAGACGTGCCTGAAGGACACGCAGGGC CCGGTGATCGCGTCGACCGACTACGTCCGCGCGCTCGCCGACCAGATCCGCGGCCAGATCGACCGCCGCTACGTCGTGCT CGGCACCGACGGCTTCGGCCGCTCGGACACGCGCGGCGCGCTGCGCCACTTCTTCGAGGTGGACCGCTACTGGGTCACGG TCGCGGCGCTCAACGCGCTCGCCGATGAAGGCACGATCGAGCGCAAGGTCGTCGCCGACGCCATCGCGAAGTACAACCTC GACCCGGCCAAGCCCAACCCGATGACGGTTTAA
Upstream 100 bases:
>100_bases GGGAGCTTGTTGCAGCTGGCGGCATGCGTCGTCGCGCGAAGGCCATCTTCAATTCCAGGACACCCAGGAGACGAGAATGT CCGCTGTACCGAATGAAGTG
Downstream 100 bases:
>100_bases CGCACGCGCCGCGCGAGCCGCGCGCCCGCTCCCGCTGTCGACGATTTCGACGAACGAAGCGGAGGCGGGTGGCGCGGCTG CGCCTTGCATGGGATCGGAG
Product: pyruvate dehydrogenase subunit E1
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 890; Mature: 890
Protein sequence:
>890_residues MKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKIPGDQDIEH RIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTED QLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGETDEPESLG AIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMRRMMEAVDG EYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQ AMNITHQQKKLPVEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLPVPALDAFE PLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQLMFYKESE TGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQH EDGHSLMWAASVPNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKGMYAFRKA DADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLLHPAEARRLSHVQTCLKDTQG PVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNL DPAKPNPMTV
Sequences:
>Translated_890_residues MKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKIPGDQDIEH RIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTED QLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGETDEPESLG AIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMRRMMEAVDG EYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQ AMNITHQQKKLPVEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLPVPALDAFE PLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQLMFYKESE TGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQH EDGHSLMWAASVPNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKGMYAFRKA DADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLLHPAEARRLSHVQTCLKDTQG PVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNL DPAKPNPMTV >Mature_890_residues MKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKIPGDQDIEH RIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTED QLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGETDEPESLG AIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMRRMMEAVDG EYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQ AMNITHQQKKLPVEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLPVPALDAFE PLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQLMFYKESE TGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQH EDGHSLMWAASVPNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKGMYAFRKA DADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLLHPAEARRLSHVQTCLKDTQG PVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNL DPAKPNPMTV
Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge
COG id: COG2609
COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=59.6610169491525, Blast_Score=1078, Evalue=0.0,
Paralogues:
None
Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004660 - InterPro: IPR009014 - InterPro: IPR015941 - InterPro: IPR005474 [H]
Pfam domain/function: PF00456 Transketolase_N [H]
EC number: =1.2.4.1 [H]
Molecular weight: Translated: 99502; Mature: 99502
Theoretical pI: Translated: 5.92; Mature: 5.92
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPY CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE INTIPVEAQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVG EEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC YNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTEDQLDNFRQEVGGNGISSYPHP CCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC WLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGETDEPESLG CCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCCHHCC AIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDA CCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHH LFARDKTGALMRRMMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNR HHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCCHHHEEEECCCCCCCEECCC GGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQAMNITHQQKKLPVEQLKKFR CCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHH DQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLPVPALDAFE HHHCCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHH PLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQ HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHCCCCC EGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYS CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEHHHHHHHH MFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLMWAASVPNCVSYDP HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCCCCCCCCCC TFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKGMYAFRKA CCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC DADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLL CCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCCCCHHHCCC HPAEARRLSHVQTCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGA CCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHH LRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNLDPAKPNPMTV HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC >Mature Secondary Structure MKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPY CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE INTIPVEAQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVG EEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC YNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTEDQLDNFRQEVGGNGISSYPHP CCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC WLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGETDEPESLG CCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCCHHCC AIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDA CCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHH LFARDKTGALMRRMMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNR HHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCCHHHEEEECCCCCCCEECCC GGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQAMNITHQQKKLPVEQLKKFR CCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHH DQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLPVPALDAFE HHHCCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHH PLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQ HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHCCCCC EGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYS CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEHHHHHHHH MFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLMWAASVPNCVSYDP HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCCCCCCCCCC TFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKGMYAFRKA CCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC DADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLL CCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCCCCHHHCCC HPAEARRLSHVQTCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGA CCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHH LRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNLDPAKPNPMTV HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8021225 [H]