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The map label for this gene is pgm [H]

Identifier: 126454166

GI number: 126454166

Start: 3039144

End: 3040562

Strand: Reverse

Name: pgm [H]

Synonym: BURPS1106A_3119

Alternate gene names: 126454166

Gene position: 3040562-3039144 (Counterclockwise)

Preceding gene: 126453349

Following gene: 126452253

Centisome position: 76.23

GC content: 68.15

Gene sequence:

>1419_bases
ATGGACGACACAGAGAGTGAATCGATGATCTCCCAATCCATCTTCAAGGCATACGATATTCGGGGCGTGATCGGCAAGAC
GCTCGACGCCGACGTCGCGCGCTCGATCGGCCGCGCATTCGGCAGCGAAGTGCGCGCGCAGGGCGGCGACGCGGTCGTCG
TCGCGCGCGACGGCCGGCTCTCGGGGCCCGAGCTCGTCGGCGCGCTCGCGGACGGGCTGCGCGCGGCGGGCGTCGATGTC
GTCGACGTCGGCATGGTGCCGACGCCCGTCGGCTACTTCGCGGCGAGCGTGCCGCTCGCGCTGTCGGGCGGCGAGCGCCG
CGTCGATTCGTGCATCGTCGTCACGGGCAGCCACAATCCGCCCGACTACAACGGTTTCAAGATGGTCCTGCGCGGCGCCG
CGATTTACGGCGACCAGATCCAGGGCCTGTACAAGCGCATCGTCGACGCGCGTTTCGAGACCGGCAACGGTTCGTATGAG
CGATACGATGTCGCCGATCAATACGTCGAGCGCATCGTCGGCGACATCAGGCTCGCGCGGCCGCTGAAGCTCGTCGTCGA
TGCGGGCAACGGCGTCGCGGGCCCGCTCGCGACGCGCCTGTTCAAGGCGCTCGGCTGCGAACTCGTCGAGCTCTTCACCG
ACATCGACGGCAACTTCCCGAACCACCACCCGGACCCGGCGCACCCGGAGAACCTGCAGGACGTGATCGCGAAGCTGAAG
ACGACCGATGCCGAGATCGGCTTCGCGTTCGACGGCGACGGCGACCGCCTCGGCGTCGTCACGAAGGACGGCCAGATCAT
CTATCCGGACCGCCAGCTGATGCTGTTCGCCGAGGAAGTGCTGTCGCGCAACCCGGGCGCGCAGATCATCTACGACGTGA
AGTGCACGCGCAATCTCGCGCAGTGGGTGCGCGAGAAGGGCGGCGAGCCGCTGATGTGGAAGACGGGCCACTCGCTCGTG
AAGGCGAAGCTGCGCGAGACGGGCGCGCCGCTCGCGGGCGAGATGAGCGGCCACGTGTTCTTCAAGGATCGCTGGTACGG
CTTCGACGACGGCCTCTACACGGGCGCGCGCCTGCTCGAGATCCTCGCGCGCGCGGCCGATCCGAGCGCGCTGCTCAACG
GCTTGCCGAACGCGGTGTCGACGCCCGAGCTGCAACTGAAGCTCGACGAAGGCGAGAACGTGAAGCTGATCGACAAGCTG
CGCGCCGACGCGAAGTTCGACGGCGCGGACGAGGTCGTGACGATCGACGGTCTGCGCGTCGAGTATCCGGACGGCTTCGG
TCTCGCGCGTTCGTCGAACACGACGCCCGTGGTCGTGCTGCGCTTCGAGGCGAGCTCCGACGCGGCGCTCGCGCGGATCC
AGGACGATTTCCGGCGCGCGCTGAAGGCGGCGAAGCCGGACGCGAACCTGCCGTTCTGA

Upstream 100 bases:

>100_bases
GGATTCGCTTCCGGCATCGGCGGTGCGTTGCGTTGCCCCCTCGCCGGTCGGTTCGGGCGAGGATTTTTTACGCATTCGCG
TTGAGGCGGCCAAATTTTTT

Downstream 100 bases:

>100_bases
GCTTGACGGCGGCGCGGCGCGCGCCGGGCGCGGCGTGCCCGAGCTTGCGCTGACGCAAGCCTTGTCCAAAAAGCGGCGAC
GCATGCGTGCGTTCGCCGCT

Product: phosphoglucomutase/phosphomannomutase family protein

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MDDTESESMISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDV
VDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYE
RYDVADQYVERIVGDIRLARPLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLK
TTDAEIGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLV
KAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKL
RADAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF

Sequences:

>Translated_472_residues
MDDTESESMISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDV
VDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYE
RYDVADQYVERIVGDIRLARPLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLK
TTDAEIGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLV
KAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKL
RADAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
>Mature_472_residues
MDDTESESMISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDV
VDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYE
RYDVADQYVERIVGDIRLARPLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLK
TTDAEIGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLV
KAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKL
RADAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=457, Percent_Identity=37.199124726477, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI1789566, Length=482, Percent_Identity=24.4813278008299, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 50979; Mature: 50979

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDTESESMISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
SGPELVGALADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNP
CCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCCCCEEEEEECCCCC
PDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLAR
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCEEECCCCCCEEHHHHHHHHHHHHHHHHHCC
PLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
TTDAEIGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLA
CCCCCEEEEECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHH
QWVREKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLE
HHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
ILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRV
HHHHCCCHHHHHHCCCCCCCCCCEEEEECCCCCEEHHHHHHCCCCCCCCCCEEEECCEEE
EYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
ECCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDDTESESMISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
SGPELVGALADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNP
CCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCCCCEEEEEECCCCC
PDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLAR
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCEEECCCCCCEEHHHHHHHHHHHHHHHHHCC
PLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
TTDAEIGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLA
CCCCCEEEEECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHH
QWVREKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLE
HHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
ILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRV
HHHHCCCHHHHHHCCCCCCCCCCEEEEECCCCCEEHHHHHHCCCCCCCCCCEEEECCEEE
EYPDGFGLARSSNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
ECCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]