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The map label for this gene is emrK [H]

Identifier: 126454055

GI number: 126454055

Start: 1596247

End: 1597434

Strand: Reverse

Name: emrK [H]

Synonym: BURPS1106A_1644

Alternate gene names: 126454055

Gene position: 1597434-1596247 (Counterclockwise)

Preceding gene: 126455101

Following gene: 126452822

Centisome position: 40.05

GC content: 71.04

Gene sequence:

>1188_bases
ATGCCCGACCCGAACGATGCCGCCGAGCGCGGCAACGACGAACGCAGCGAGCACGACGAACCCGGCCGCGAACGCGCGCG
CGGGCGCCGCGAAGAGGCCGACGCCCACGCGCGCGACGCGCGGCCCGGCGACGCGCCTTCCGGCGAGCGCAAGCGGCCCG
GCAAGAAACCGCTCGTCGTGCTCGCGATCATCGTCGTGCTGCTGCTCGTCGGCGCGTTCGTCTGGTGGTTCGCGACGCGC
AATCAGGTCAGCACCGACGACGCCTACACCGACGGCAACGCGATCACGATCGCGCCGAAGGTGTCCGGCTACGTCGTCGC
GCTCGCGATCGACGACAACGTCTACGTCCATCGCGGCGATCTGCTGCTCGTGATCGACAAGCGCGACTATCAGGCGCAAG
TCGACGCGGCGCGCGCGCAGCTCGGGCTCGCGCAGGCGCAGCTCGACGCCGCGCAGGTGCAGCTCGACATCGCGCACGTG
CAGTTCCCCGCGCAATACCGGCAGGCGCAGGCGCAGATCGAGGCCGCGCAGGCGAGCTTCAGGCAGGCGCTCGCCGCGTA
CGAGCGGCAGCACGCGGTCGACGCGCGCGCGACATCGCAGCAGGCGATCGACGTCGCCGACGCGCAACGGCTCACCGCCG
ACGCGAACGTCGCGACCGCCCGCGCGCAGGCGCGCACCGCGAGCCTCGTGCCGCAGCAGATCCGGCAGGCTCAGACCGCG
GTCGAGCAGCGCCGCCAGCAGGTGCTGCAGGCGCAAGCGCAGCTCGAGGCCGCCCAGCTCGCGCTGTCGTACTGCGAAGT
GCGCGCGCCGTCCGACGGCTGGATCACGCGCCGCAACGTGCAGCTCGGCTCGTTCCTGCAGGCGGGCGCGGCGCTCTTCG
CGATCGTCACGCCGCAGCTGTGGGTGACGGCGAATTTCAAGGAATCGCAGCTCGAGCGCATGCGCGCCGGCGATCGCGTG
AGCGTGTCGGTCGACGCGTATCCGAACCTCGAGCTGCACGGCCACGTCGACAGCATCCAGCTCGGCAGCGGCTCGCGCTT
CTCCGCGTTTCCGCCGGAGAACGCGACCGGCAATTTCGTGAAGATCGTTCAGCGCGTGCCGGTGAAGATCGCGATCGACG
GCGGCCTGCCGCGCGATCCGCCGCTCGGAATCGGGCTGTCGGTCGTGCCGAAGGTGTATCTGAAATGA

Upstream 100 bases:

>100_bases
GGCAAACGGGAAGCGAGCAGCGAGTCGCGGCCCGTCGCGCGCCCCGCGACCCGAATCGCCGGCGCGCCTTGTGGTGGCCG
GCGCACAGGAGCGAAGCGCG

Downstream 100 bases:

>100_bases
CGATGACATCGATCACGGCGACGGCGAAGACTCGCAATCATGCGCCGACCGAACCGGGCGCCGCGCGTGATGCGCGGCAC
CGTATCCATCCCGTTCGCCG

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPDPNDAAERGNDERSEHDEPGRERARGRREEADAHARDARPGDAPSGERKRPGKKPLVVLAIIVVLLLVGAFVWWFATR
NQVSTDDAYTDGNAITIAPKVSGYVVALAIDDNVYVHRGDLLLVIDKRDYQAQVDAARAQLGLAQAQLDAAQVQLDIAHV
QFPAQYRQAQAQIEAAQASFRQALAAYERQHAVDARATSQQAIDVADAQRLTADANVATARAQARTASLVPQQIRQAQTA
VEQRRQQVLQAQAQLEAAQLALSYCEVRAPSDGWITRRNVQLGSFLQAGAALFAIVTPQLWVTANFKESQLERMRAGDRV
SVSVDAYPNLELHGHVDSIQLGSGSRFSAFPPENATGNFVKIVQRVPVKIAIDGGLPRDPPLGIGLSVVPKVYLK

Sequences:

>Translated_395_residues
MPDPNDAAERGNDERSEHDEPGRERARGRREEADAHARDARPGDAPSGERKRPGKKPLVVLAIIVVLLLVGAFVWWFATR
NQVSTDDAYTDGNAITIAPKVSGYVVALAIDDNVYVHRGDLLLVIDKRDYQAQVDAARAQLGLAQAQLDAAQVQLDIAHV
QFPAQYRQAQAQIEAAQASFRQALAAYERQHAVDARATSQQAIDVADAQRLTADANVATARAQARTASLVPQQIRQAQTA
VEQRRQQVLQAQAQLEAAQLALSYCEVRAPSDGWITRRNVQLGSFLQAGAALFAIVTPQLWVTANFKESQLERMRAGDRV
SVSVDAYPNLELHGHVDSIQLGSGSRFSAFPPENATGNFVKIVQRVPVKIAIDGGLPRDPPLGIGLSVVPKVYLK
>Mature_394_residues
PDPNDAAERGNDERSEHDEPGRERARGRREEADAHARDARPGDAPSGERKRPGKKPLVVLAIIVVLLLVGAFVWWFATRN
QVSTDDAYTDGNAITIAPKVSGYVVALAIDDNVYVHRGDLLLVIDKRDYQAQVDAARAQLGLAQAQLDAAQVQLDIAHVQ
FPAQYRQAQAQIEAAQASFRQALAAYERQHAVDARATSQQAIDVADAQRLTADANVATARAQARTASLVPQQIRQAQTAV
EQRRQQVLQAQAQLEAAQLALSYCEVRAPSDGWITRRNVQLGSFLQAGAALFAIVTPQLWVTANFKESQLERMRAGDRVS
VSVDAYPNLELHGHVDSIQLGSGSRFSAFPPENATGNFVKIVQRVPVKIAIDGGLPRDPPLGIGLSVVPKVYLK

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=354, Percent_Identity=31.3559322033898, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1789041, Length=363, Percent_Identity=31.404958677686, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1790519, Length=308, Percent_Identity=30.5194805194805, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789637, Length=336, Percent_Identity=25.5952380952381, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081951, Length=339, Percent_Identity=27.7286135693215, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790024, Length=255, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790012, Length=249, Percent_Identity=26.5060240963855, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787013, Length=315, Percent_Identity=28.2539682539683, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789900, Length=321, Percent_Identity=26.1682242990654, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43004; Mature: 42873

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPNDAAERGNDERSEHDEPGRERARGRREEADAHARDARPGDAPSGERKRPGKKPLVV
CCCCCCHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
LAIIVVLLLVGAFVWWFATRNQVSTDDAYTDGNAITIAPKVSGYVVALAIDDNVYVHRGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCEEEEECC
LLLVIDKRDYQAQVDAARAQLGLAQAQLDAAQVQLDIAHVQFPAQYRQAQAQIEAAQASF
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHHHHHH
RQALAAYERQHAVDARATSQQAIDVADAQRLTADANVATARAQARTASLVPQQIRQAQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VEQRRQQVLQAQAQLEAAQLALSYCEVRAPSDGWITRRNVQLGSFLQAGAALFAIVTPQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHEEEEECCCE
WVTANFKESQLERMRAGDRVSVSVDAYPNLELHGHVDSIQLGSGSRFSAFPPENATGNFV
EEEECCCHHHHHHHHCCCEEEEEECCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCHHH
KIVQRVPVKIAIDGGLPRDPPLGIGLSVVPKVYLK
HHHHHCCEEEEECCCCCCCCCCCCCHHHHCHHHCC
>Mature Secondary Structure 
PDPNDAAERGNDERSEHDEPGRERARGRREEADAHARDARPGDAPSGERKRPGKKPLVV
CCCCCHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
LAIIVVLLLVGAFVWWFATRNQVSTDDAYTDGNAITIAPKVSGYVVALAIDDNVYVHRGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCEEEEECC
LLLVIDKRDYQAQVDAARAQLGLAQAQLDAAQVQLDIAHVQFPAQYRQAQAQIEAAQASF
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHHHHHH
RQALAAYERQHAVDARATSQQAIDVADAQRLTADANVATARAQARTASLVPQQIRQAQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VEQRRQQVLQAQAQLEAAQLALSYCEVRAPSDGWITRRNVQLGSFLQAGAALFAIVTPQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHEEEEECCCE
WVTANFKESQLERMRAGDRVSVSVDAYPNLELHGHVDSIQLGSGSRFSAFPPENATGNFV
EEEECCCHHHHHHHHCCCEEEEEECCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCHHH
KIVQRVPVKIAIDGGLPRDPPLGIGLSVVPKVYLK
HHHHHCCEEEEECCCCCCCCCCCCCHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]