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The map label for this gene is paaK [H]

Identifier: 126453980

GI number: 126453980

Start: 3740287

End: 3741375

Strand: Direct

Name: paaK [H]

Synonym: BURPS1106A_3840

Alternate gene names: 126453980

Gene position: 3740287-3741375 (Clockwise)

Preceding gene: 126452809

Following gene: 126455139

Centisome position: 93.78

GC content: 67.86

Gene sequence:

>1089_bases
ATGGCGACTCCGCAATTCCATCCGCTGCGCATTCGCGACGTGCGGCCCGAAACCGCCGACGCCGTCACGGTGTCGTTCGA
AGTGCCGCCCGAGCTGCGCGACGCTTACCGCTTCACGCAAGGCCAGTTCGTCACGCTGAAGGCGCACGTCGACGGCGAGG
AAACCCGCCGCTCGTATTCGATCTGCGTCGGCACGACGGATTACGACCGCGACGGCGAGTTGCGCATCGGCATCAAGCGC
GTGCGCGGCGGCCGCTTCTCGAACTTCGCGTTCGATACGCTCAAGCCCGGCCACACGATCGACGTGATGACGCCGGACGG
CCGCTTCTTCACGCACCTGAACGCCGGGCACGGCAAGCAGTACGTCGCGTTCGCGGGCGGCTCGGGGATCACGCCCGTGC
TCGCGATCGTCAAGACGACGCTCGAGCTCGAGCCGCGCAGCACGTTCACGCTGATCTACGGCAACCGCAGCGTCGATTCG
ATCATGTTCGCCGAGGAACTCGAGGACCTGAAGAACCGCTTCATGCAGCGGCTCGCCCTCTACCACGTGCTGTCCGACGA
CGTGCAGGACGTCGAGCTGTTCAACGGCGTGCTCGATCAGGCGAAATGCGCGGCGTTTCTCGATTCGCTCGTGCCGGCCG
CGACGATCGACGAGGCGTTCATCTGCGGGCCGGCGCCGATGATGGACGCCGCGGAAGCCGCGCTCGCCGCGGCCGGCGTG
CCGCGCGAGCGCGTGCATGTCGAGCGCTTCGGCACGCCGCTGCCGCAGGCGGGCGCGCCCGCCGTCGAAATCACCGCCGA
CACGCCCGCCGCCGACCTCGAAATCGTGCTCGACGGCAAGAAGCGCAAGCTGCGGCTGCCGTACGAAGGCGCGAGCCTCC
TCGATGTCGGGCTGCGCGCGGGCCTCGCGCTGCCGTACGCGTGCAAGGGCGGCGTCTGCTGCACGTGCCGCGCGAAGGTG
CTCGAAGGCGAGGTGCGGATGGAGAAGAACTACACGCTGGAGCCGCAGGAGATCGCCGACGGATTCGTGCTCACCTGCCA
GTGCCATCCGGTCAGCGAGAAGATCGTCGTCAGCTACGACGAACGGTAG

Upstream 100 bases:

>100_bases
CATACCGAGCGGCTCGCGCAATTCGCGTCGACCGCGTGCAAGGCGCTCTATCGCTGCCTCGACTGCCGCGAACCCTTCGA
CTACTTCAAACCTTATTGAT

Downstream 100 bases:

>100_bases
GCGGCGTCTTGCCGCGCGGTTACGCGCGGCCCGCCATCTCGCTTACACTAGGGGCCGCCTGCGGGCCGGACGCGCGACGC
GCCGGCCCGCAGGCGGCTTT

Product: phenylacetate-CoA oxygenase/reductase, PaaK subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MATPQFHPLRIRDVRPETADAVTVSFEVPPELRDAYRFTQGQFVTLKAHVDGEETRRSYSICVGTTDYDRDGELRIGIKR
VRGGRFSNFAFDTLKPGHTIDVMTPDGRFFTHLNAGHGKQYVAFAGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDS
IMFAEELEDLKNRFMQRLALYHVLSDDVQDVELFNGVLDQAKCAAFLDSLVPAATIDEAFICGPAPMMDAAEAALAAAGV
PRERVHVERFGTPLPQAGAPAVEITADTPAADLEIVLDGKKRKLRLPYEGASLLDVGLRAGLALPYACKGGVCCTCRAKV
LEGEVRMEKNYTLEPQEIADGFVLTCQCHPVSEKIVVSYDER

Sequences:

>Translated_362_residues
MATPQFHPLRIRDVRPETADAVTVSFEVPPELRDAYRFTQGQFVTLKAHVDGEETRRSYSICVGTTDYDRDGELRIGIKR
VRGGRFSNFAFDTLKPGHTIDVMTPDGRFFTHLNAGHGKQYVAFAGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDS
IMFAEELEDLKNRFMQRLALYHVLSDDVQDVELFNGVLDQAKCAAFLDSLVPAATIDEAFICGPAPMMDAAEAALAAAGV
PRERVHVERFGTPLPQAGAPAVEITADTPAADLEIVLDGKKRKLRLPYEGASLLDVGLRAGLALPYACKGGVCCTCRAKV
LEGEVRMEKNYTLEPQEIADGFVLTCQCHPVSEKIVVSYDER
>Mature_361_residues
ATPQFHPLRIRDVRPETADAVTVSFEVPPELRDAYRFTQGQFVTLKAHVDGEETRRSYSICVGTTDYDRDGELRIGIKRV
RGGRFSNFAFDTLKPGHTIDVMTPDGRFFTHLNAGHGKQYVAFAGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDSI
MFAEELEDLKNRFMQRLALYHVLSDDVQDVELFNGVLDQAKCAAFLDSLVPAATIDEAFICGPAPMMDAAEAALAAAGVP
RERVHVERFGTPLPQAGAPAVEITADTPAADLEIVLDGKKRKLRLPYEGASLLDVGLRAGLALPYACKGGVCCTCRAKVL
EGEVRMEKNYTLEPQEIADGFVLTCQCHPVSEKIVVSYDER

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI49574502, Length=217, Percent_Identity=27.1889400921659, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787658, Length=357, Percent_Identity=47.0588235294118, Blast_Score=327, Evalue=8e-91,
Organism=Escherichia coli, GI1787098, Length=344, Percent_Identity=25.8720930232558, Blast_Score=111, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6322146, Length=220, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39700; Mature: 39569

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPQFHPLRIRDVRPETADAVTVSFEVPPELRDAYRFTQGQFVTLKAHVDGEETRRSYS
CCCCCCCCEEEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEEECCCHHHCCEEE
ICVGTTDYDRDGELRIGIKRVRGGRFSNFAFDTLKPGHTIDVMTPDGRFFTHLNAGHGKQ
EEEECCCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCEEEEEECCCCCE
YVAFAGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDSIMFAEELEDLKNRFMQRLAL
EEEEECCCCCHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
YHVLSDDVQDVELFNGVLDQAKCAAFLDSLVPAATIDEAFICGPAPMMDAAEAALAAAGV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCC
PRERVHVERFGTPLPQAGAPAVEITADTPAADLEIVLDGKKRKLRLPYEGASLLDVGLRA
CHHHEEHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHC
GLALPYACKGGVCCTCRAKVLEGEVRMEKNYTLEPQEIADGFVLTCQCHPVSEKIVVSYD
CCCCCCCCCCCEEEEEEHEECCCEEEECCCCCCCHHHHCCCEEEEEEECCCCCEEEEEEC
ER
CC
>Mature Secondary Structure 
ATPQFHPLRIRDVRPETADAVTVSFEVPPELRDAYRFTQGQFVTLKAHVDGEETRRSYS
CCCCCCCEEEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEEECCCHHHCCEEE
ICVGTTDYDRDGELRIGIKRVRGGRFSNFAFDTLKPGHTIDVMTPDGRFFTHLNAGHGKQ
EEEECCCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCEEEEEECCCCCE
YVAFAGGSGITPVLAIVKTTLELEPRSTFTLIYGNRSVDSIMFAEELEDLKNRFMQRLAL
EEEEECCCCCHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
YHVLSDDVQDVELFNGVLDQAKCAAFLDSLVPAATIDEAFICGPAPMMDAAEAALAAAGV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCC
PRERVHVERFGTPLPQAGAPAVEITADTPAADLEIVLDGKKRKLRLPYEGASLLDVGLRA
CHHHEEHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHC
GLALPYACKGGVCCTCRAKVLEGEVRMEKNYTLEPQEIADGFVLTCQCHPVSEKIVVSYD
CCCCCCCCCCCEEEEEEHEECCCEEEECCCCCCCHHHHCCCEEEEEEECCCCCEEEEEEC
ER
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]