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The map label for this gene is nanT [H]

Identifier: 126453926

GI number: 126453926

Start: 1766778

End: 1768004

Strand: Reverse

Name: nanT [H]

Synonym: BURPS1106A_1806

Alternate gene names: 126453926

Gene position: 1768004-1766778 (Counterclockwise)

Preceding gene: 126454782

Following gene: 126452031

Centisome position: 44.33

GC content: 66.83

Gene sequence:

>1227_bases
ATGGCCATGAGCTGGACCCGGGAGCAACGCAACGTCACGATCGCCGCCTATCTCGGCTGGACGCTCGACGCGTTCGACTT
CTTCCTGATGGTCTTCGTGCTGAAGGACATCGCCGCCGAATTCAACACGAAGATTCCCGCCGTCGCGTTCGCGATCACGC
TGACGCTCGCCGCGCGCCCGATCGGCGCGCTGATCTTCGGCCGCCTCGCCGATCACTTCGGCCGCCGGCCGACGCTGATG
ATCAACATCGCGTGCTACTCGCTGCTCGAGCTCGCGTCCGGCTTCGCGCCGAGCCTCGCCGCGCTGCTCGTGCTGCGCAC
GCTGTTCGGCGTCGCGATGGGCGGCGAATGGGGCGTCGGCTCCGCGCTGACGATGGAGACGGTTCCGCCGCGCGCGCGCG
GCGCGGTGTCGGGCCTGCTGCAGGCGGGCTATCCGAGCGGCTACCTGCTCGCGTCGGTCGTCTTCGGCCTGCTCTACCCG
TACATCGGCTGGCGCGGCATGTTCATGATCGGCGTGCTGCCCGCGCTGCTCGTGCTGTACGTGCGCGCGAAAGTGCCCGA
ATCGCCCGCGTGGAAGCAGATGGAAAAGCGCGCGCGGCCGGGCCTCGTCGCCACGCTCAAGCAGAACTGGAAACTGTCGA
TCTATGCAGTCGTCCTGATGACCGCGTTCAACTTCTTCTCGCACGGCACGCAGGATCTCTACCCGACTTTCCTGCGCGAG
CAGCATCACTTCGATCCGCATACGGTGTCGTGGATCACGATCGTGCTGAACATCGGCGCGATCGTGGGCGGCCTCACGTT
CGGCTGGTTGTCCGAACGCATCGGCCGGCGCCGCGCGATCTTCATCGCCGCGATGATCGCGCTGCCCGTGCTGCCGCTGT
GGGCGTTCTCGACCGGCGCGCTCGCGCTCGCCGCGGGCGCGTTCCTGATGCAGATCTCGGTGCAGGGCGCGTGGGGCGTG
ATCCCCGTGCACCTGAACGAGATTTCACCGGACGAGATTCGCGCGACGTTCCCCGGCTTCGTCTATCAGCTCGGCAACCT
GCTCGCGTCGGGCAACGCGACGCTGCAGGCGCAGTTCGCGGTCGATCACGGCAACAACTACGGCATGGCGCTCGCGACGG
TCGCGGGCATCGTCGCCGTCGTCATCTGCGTTTTAATTGTGTTCAGCCGCGAACGACGCGGAATCGACATGACGCAGACG
GCCGCGATGAGCCCGACCAGCGGATGA

Upstream 100 bases:

>100_bases
GCGCGCGGCGAGCGGCGTACACTCGCGTTACCGCCCGCGCGCAGCGCCGGCCGGGCGGTGCGGAGCACGACGGCGCTTCC
CAATCGAGGAGACCGTCGCC

Downstream 100 bases:

>100_bases
GCTCGCGCGCGGCGGCGCACCATCGCGCAACGGTACGTTGCGCTGCGTGCGGCAGGCCGTTCGTGCTGCATCGCACCGAA
CGCTCTAGAGGACTTTGTCC

Product: major facilitator superfamily transporter sialate:H(+) symporter

Products: NA

Alternate protein names: Sialic acid permease [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKIPAVAFAITLTLAARPIGALIFGRLADHFGRRPTLM
INIACYSLLELASGFAPSLAALLVLRTLFGVAMGGEWGVGSALTMETVPPRARGAVSGLLQAGYPSGYLLASVVFGLLYP
YIGWRGMFMIGVLPALLVLYVRAKVPESPAWKQMEKRARPGLVATLKQNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLRE
QHHFDPHTVSWITIVLNIGAIVGGLTFGWLSERIGRRRAIFIAAMIALPVLPLWAFSTGALALAAGAFLMQISVQGAWGV
IPVHLNEISPDEIRATFPGFVYQLGNLLASGNATLQAQFAVDHGNNYGMALATVAGIVAVVICVLIVFSRERRGIDMTQT
AAMSPTSG

Sequences:

>Translated_408_residues
MAMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKIPAVAFAITLTLAARPIGALIFGRLADHFGRRPTLM
INIACYSLLELASGFAPSLAALLVLRTLFGVAMGGEWGVGSALTMETVPPRARGAVSGLLQAGYPSGYLLASVVFGLLYP
YIGWRGMFMIGVLPALLVLYVRAKVPESPAWKQMEKRARPGLVATLKQNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLRE
QHHFDPHTVSWITIVLNIGAIVGGLTFGWLSERIGRRRAIFIAAMIALPVLPLWAFSTGALALAAGAFLMQISVQGAWGV
IPVHLNEISPDEIRATFPGFVYQLGNLLASGNATLQAQFAVDHGNNYGMALATVAGIVAVVICVLIVFSRERRGIDMTQT
AAMSPTSG
>Mature_407_residues
AMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKIPAVAFAITLTLAARPIGALIFGRLADHFGRRPTLMI
NIACYSLLELASGFAPSLAALLVLRTLFGVAMGGEWGVGSALTMETVPPRARGAVSGLLQAGYPSGYLLASVVFGLLYPY
IGWRGMFMIGVLPALLVLYVRAKVPESPAWKQMEKRARPGLVATLKQNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLREQ
HHFDPHTVSWITIVLNIGAIVGGLTFGWLSERIGRRRAIFIAAMIALPVLPLWAFSTGALALAAGAFLMQISVQGAWGVI
PVHLNEISPDEIRATFPGFVYQLGNLLASGNATLQAQFAVDHGNNYGMALATVAGIVAVVICVLIVFSRERRGIDMTQTA
AMSPTSG

Specific function: May be a sugar-cation symporter involved in sialic acid uptake [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter family. Sialic acid transporter (TC 2.A.1.12.1) subfamily [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=192, Percent_Identity=27.0833333333333, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082404, Length=353, Percent_Identity=28.328611898017, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI87082231, Length=450, Percent_Identity=27.3333333333333, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790550, Length=417, Percent_Identity=26.378896882494, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788292, Length=451, Percent_Identity=24.6119733924612, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786229, Length=388, Percent_Identity=25.5154639175258, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081723, Length=338, Percent_Identity=28.1065088757396, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789941, Length=428, Percent_Identity=25, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082159, Length=140, Percent_Identity=33.5714285714286, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17542342, Length=135, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86562855, Length=179, Percent_Identity=30.7262569832402, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984734, Length=203, Percent_Identity=29.5566502463054, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322632, Length=435, Percent_Identity=27.5862068965517, Blast_Score=155, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004742 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44245; Mature: 44114

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKIPAVAFAITLTLAARP
CCCCCCCHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IGALIFGRLADHFGRRPTLMINIACYSLLELASGFAPSLAALLVLRTLFGVAMGGEWGVG
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
SALTMETVPPRARGAVSGLLQAGYPSGYLLASVVFGLLYPYIGWRGMFMIGVLPALLVLY
CEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRAKVPESPAWKQMEKRARPGLVATLKQNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLRE
HHHCCCCCCHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QHHFDPHTVSWITIVLNIGAIVGGLTFGWLSERIGRRRAIFIAAMIALPVLPLWAFSTGA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
LALAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGFVYQLGNLLASGNATLQAQFA
HHHHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEE
VDHGNNYGMALATVAGIVAVVICVLIVFSRERRGIDMTQTAAMSPTSG
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
AMSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKIPAVAFAITLTLAARP
CCCCCCHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IGALIFGRLADHFGRRPTLMINIACYSLLELASGFAPSLAALLVLRTLFGVAMGGEWGVG
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
SALTMETVPPRARGAVSGLLQAGYPSGYLLASVVFGLLYPYIGWRGMFMIGVLPALLVLY
CEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRAKVPESPAWKQMEKRARPGLVATLKQNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLRE
HHHCCCCCCHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QHHFDPHTVSWITIVLNIGAIVGGLTFGWLSERIGRRRAIFIAAMIALPVLPLWAFSTGA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
LALAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGFVYQLGNLLASGNATLQAQFA
HHHHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEE
VDHGNNYGMALATVAGIVAVVICVLIVFSRERRGIDMTQTAAMSPTSG
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA