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The map label for this gene is hisE

Identifier: 126453907

GI number: 126453907

Start: 3630448

End: 3630816

Strand: Reverse

Name: hisE

Synonym: BURPS1106A_3716

Alternate gene names: 126453907

Gene position: 3630816-3630448 (Counterclockwise)

Preceding gene: 126454802

Following gene: 126452972

Centisome position: 91.03

GC content: 67.48

Gene sequence:

>369_bases
ATGACGCAATCGACGACCGAAGACACGCTGCTGCGTCTCGCCGCCGTGATCGACAGCCGCAAGGGCGGCGATCCCGAGCA
ATCGTACGTGTCGCGCCTCTTTCACAAGGGCGACGACGCGATCCTGAAGAAGATCGGCGAGGAAGCGACCGAAGTCGTGC
TCGCCGCGAAGGACGTGCGCCAGGGCGGCGCGCCGTCGGCGCTCGTCGGCGAGGTCGCGGACCTGTGGTTCCACTGCCTC
GTCGCGCTGTCGCATTTCGACCTGAGCCCCGCCGACGTGATCGCCGAGCTCGAACGCCGCGAAGGCATGTCGGGCATCGA
GGAAAAGGCGCTGCGCAAGCGCCGCGAGCGCGAGGAAAACGGCGGTTGA

Upstream 100 bases:

>100_bases
GCCGGCGCTCGTGCTTTTTCCAGAAATTCGAGGGCACCGTCGACGACGGCGAATGGGTCGCGGTCGATCCGGTGCTCAAA
GATCCCGAACATATCTACAA

Downstream 100 bases:

>100_bases
GCCAATGCGGCCACGCGCCGCGTAAGTTTTGTCATCAAAGGGGAATAGCATCATGCCGGAGTCGCCGAACCAATTTCCGC
CGTCGTACCAGAGCGCGACC

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MTQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCL
VALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG

Sequences:

>Translated_122_residues
MTQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCL
VALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG
>Mature_121_residues
TQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLV
ALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_BURM7 (A3MPU2)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001082278.1
- ProteinModelPortal:   A3MPU2
- SMR:   A3MPU2
- GeneID:   4892977
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_2757
- TIGR:   BMA10247_2757
- HOGENOM:   HBG646527
- OMA:   ETVMAAK
- ProtClustDB:   PRK00400
- BioCyc:   BMAL320389:BMA10247_2757-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 13361; Mature: 13230

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVR
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QGGAPSALVGEVADLWFHCLVALSHFDLSPADVIAELERREGMSGIEEKALRKRREREEN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GG
CC
>Mature Secondary Structure 
TQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVR
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QGGAPSALVGEVADLWFHCLVALSHFDLSPADVIAELERREGMSGIEEKALRKRREREEN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA