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The map label for this gene is nudF [H]

Identifier: 126453829

GI number: 126453829

Start: 1286215

End: 1286805

Strand: Direct

Name: nudF [H]

Synonym: BURPS1106A_1314

Alternate gene names: 126453829

Gene position: 1286215-1286805 (Clockwise)

Preceding gene: 126454747

Following gene: 126453643

Centisome position: 32.25

GC content: 63.79

Gene sequence:

>591_bases
ATGGCCGATTTGCCGAATCACGACGCCACCCTCACCGAAACTTGCATCGAAAGCGAATCCGTCTACGACGGCGCGTTCCT
GAAGGTCAAGCGCGACACCGTTCGTCTGCCGGACGGCAAGCATGCGACGCGCGAATACGTGACGCATCCGGGCGCGGTGA
TGGTCATCCCGCTGTTCGACGACGGCCGCGTGCTGATGGAAAGCCAGTACCGCTATCCGATCGGCAAGGTGATGGCCGAG
TTTCCGGCGGGCAAGCTCGATCCGAACGAAGGCGCGCTCGCCTGCGCGGTGCGCGAACTGCGTGAGGAAACCGGCTACAC
CGCGCGCGAATACGTGTTCCTCACGCGCATTCATCCGATCATCTCGTATTCGACCGAATTCATCGATATCTATCTCGCGC
GCGGCCTGACGGCGGGCGAGCGCAAGCTCGACGACGGCGAGTTCCTCGAGACGTTCACGGCGACGCTGCCGGACCTGCTC
GAGTGGGTGCGCACCGGCCGGATCAGCGACGTCAAGACGATCATCGGCACGATGTGGCTCGAGAAGGCGGTATCGGGCGC
ATGGCCGCTCGGTGACGTGATCCGGCCGTAG

Upstream 100 bases:

>100_bases
CAGTCTCTTCGTGGTGTTCGCGTTTCCCGGCTTCACGTTCCAGTATCTCGTCAAACGGCGCTGACGGCGTAGGCCGTCGC
GCCCCACTGCGGAGCCGCCG

Downstream 100 bases:

>100_bases
CGCTGCTGCGCGCCGAGCGGGGTAGTTTGCGAAGGGATACAATCGGTGCCGACGGTCGGCGCGATCGGGGTCCTCTTTCT
CGGACTTAATTTAGCACGGT

Product: NUDIX family hydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MADLPNHDATLTETCIESESVYDGAFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFDDGRVLMESQYRYPIGKVMAE
FPAGKLDPNEGALACAVRELREETGYTAREYVFLTRIHPIISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLL
EWVRTGRISDVKTIIGTMWLEKAVSGAWPLGDVIRP

Sequences:

>Translated_196_residues
MADLPNHDATLTETCIESESVYDGAFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFDDGRVLMESQYRYPIGKVMAE
FPAGKLDPNEGALACAVRELREETGYTAREYVFLTRIHPIISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLL
EWVRTGRISDVKTIIGTMWLEKAVSGAWPLGDVIRP
>Mature_195_residues
ADLPNHDATLTETCIESESVYDGAFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFDDGRVLMESQYRYPIGKVMAEF
PAGKLDPNEGALACAVRELREETGYTAREYVFLTRIHPIISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLLE
WVRTGRISDVKTIIGTMWLEKAVSGAWPLGDVIRP

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 21983; Mature: 21852

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLPNHDATLTETCIESESVYDGAFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFD
CCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCEEECCCCCHHHHHHHCCCCCEEEEEEEC
DGRVLMESQYRYPIGKVMAEFPAGKLDPNEGALACAVRELREETGYTAREYVFLTRIHPI
CCCEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEHHHHHHHH
ISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLLEWVRTGRISDVKTIIGTMWL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EKAVSGAWPLGDVIRP
HHHHCCCCCCHHCCCC
>Mature Secondary Structure 
ADLPNHDATLTETCIESESVYDGAFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFD
CCCCCCCCHHHHHHHCCCCCCCCEEEEEECCEEECCCCCHHHHHHHCCCCCEEEEEEEC
DGRVLMESQYRYPIGKVMAEFPAGKLDPNEGALACAVRELREETGYTAREYVFLTRIHPI
CCCEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEHHHHHHHH
ISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLLEWVRTGRISDVKTIIGTMWL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EKAVSGAWPLGDVIRP
HHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]