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The map label for this gene is paaF [H]

Identifier: 126453651

GI number: 126453651

Start: 3485326

End: 3486624

Strand: Direct

Name: paaF [H]

Synonym: BURPS1106A_3577

Alternate gene names: 126453651

Gene position: 3485326-3486624 (Clockwise)

Preceding gene: 126452791

Following gene: 126452695

Centisome position: 87.39

GC content: 65.82

Gene sequence:

>1299_bases
ATGGCAACCTCGCTTCCGCTCGACCCGATCGAACGAGCGAGCCGCGACGAACTGCTCGCGCTTCAGCTCGACCGCCTGAA
ATGGTCACTCGCCCACGCGTACGAGAACTCGCCCGTCTATCGGCGCAAGTTCGACGAGGCGGGCGTGCACCCGGCCGATC
TGAAAACGCTTGCGGATCTGAGCCGCTTTCCGTTCACGACGAAGAACGATCTGCGCGACAACTATCCGTTCGGCATGTTC
GCCGTGCCGCAGGAGCGCATCTCGCGCATCCACGCTTCGTCAGGCACGACGGGCAAGCCGACGGTGGTCGGCTATACCGC
GCGGGACATCGATACCTGGGCGGGCCTCGTCGCACGCTCGATCCGCGCGGCGGGCGCGCGGCCGGGCGACAAGGTGCATG
TGAGCTACGGCTACGGCCTCTTCACGGGCGGCCTGGGCGCGCATTACGGCGCCGAGCGGGCCGGGCTGACGGTGATCCCG
TTCGGCGGCGGCCAGACCGAAAAGCAGGTGCAACTGATCCAGGACTTCCGGCCCGATATCATCATGGTGACGCCCAGCTA
CATGCTGTCGATCGCCGACGAAATGGAACGTCAGCACCTCGATCCCGCCCAGTGCTCGCTGCGAATCGGCATCTTCGGCG
CGGAACCGTGGACCAACGACATGCGCGTCGCAATCGAGCAGCGCATGGGCATCGACGCCGTCGACATCTATGGGCTCTCC
GAGGTGATCGGCCCGGGCGTCGCATCGGAGTGCGTCGAAACGAAGGACGGCCCGACGATCTGGGAAGATCACTTCTACCC
CGAGATCATCGATCCCGACACCGGCGAAGTGCTGCCGGACGGCGCATTCGGCGAACTCGTGTTCACGTCGCTCACGAAGG
AAGCGCTGCCGATCGTCCGCTACCGGACCCGCGACCTCACCCGCCTGCTGCCCGGCACCGCGCGTACGATGCGCAGGATG
GAAAAAATCACCGGCCGTTCGGACGACATGATGATCGTGCGCGGCGTGAACGTGTTCCCGACCCAGCTCGAAGAGCAATT
GCTCAAGCAGCGTGCGCTCGCGCCTCACTATCAGGTGGTGCTGACGAAGGACGGGCCGCTCGACGTGCTGACGCTCAACG
TCGAGCCCTGCCCGGAGACGGCGCCGGATGCGGCCGCGATCGACGCCGCACGCCGCGCGCTCGCGCACGACATCAAATCG
CTGATTGGCGTGACGGCGATCATCAACGTGTTGCCCGTCAACGGCATCGAGCGCTCGGTCGGCAAGGCGAGACGAATCGT
CGACAAGCGGCGGCCGTGA

Upstream 100 bases:

>100_bases
GTCGCGATGTTCCGCGGCAAGTCGACTCAAATCAAAGGGACGGTGATCCCTGTAGACCGTTAGCGTCCACGCACGCTCAC
ATAAATATATTGGAGACATC

Downstream 100 bases:

>100_bases
CGTTTCGCGCATGGCGGCTGGGCAGCCCGCACGTGTGCGCGCTTGCGGGCCCGGGCCGCCTGAGGAAAGATCGCCGCGCG
GGGCGCGGCGGCGCGCATCA

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADLSRFPFTTKNDLRDNYPFGMF
AVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARSIRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVVLTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKS
LIGVTAIINVLPVNGIERSVGKARRIVDKRRP

Sequences:

>Translated_432_residues
MATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADLSRFPFTTKNDLRDNYPFGMF
AVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARSIRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVVLTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKS
LIGVTAIINVLPVNGIERSVGKARRIVDKRRP
>Mature_431_residues
ATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADLSRFPFTTKNDLRDNYPFGMFA
VPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARSIRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPF
GGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLSE
VIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVRYRTRDLTRLLPGTARTMRRME
KITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVVLTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKSL
IGVTAIINVLPVNGIERSVGKARRIVDKRRP

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=436, Percent_Identity=64.4495412844037, Blast_Score=584, Evalue=1e-168,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47667; Mature: 47536

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADL
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKNDLRDNYPFGMFAVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARS
HHCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EEECHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHCCHH
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVR
HHHCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKSLIGVTAIINVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRIVDKRRP
HHHHHHHHCCCC
>Mature Secondary Structure 
ATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADL
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKNDLRDNYPFGMFAVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARS
HHCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EEECHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHCCHH
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVR
HHHCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKSLIGVTAIINVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRIVDKRRP
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]