| Definition | Burkholderia pseudomallei 1106a chromosome I, complete genome. |
|---|---|
| Accession | NC_009076 |
| Length | 3,988,455 |
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The map label for this gene is polS [H]
Identifier: 126453608
GI number: 126453608
Start: 855632
End: 856408
Strand: Direct
Name: polS [H]
Synonym: BURPS1106A_0872
Alternate gene names: 126453608
Gene position: 855632-856408 (Clockwise)
Preceding gene: 126453351
Following gene: 126452357
Centisome position: 21.45
GC content: 70.01
Gene sequence:
>777_bases GTGAGACTGCAGGAGAAGGTCGCGATCCTGACGGGCGCGGCAAGCGGCATCGGCGAAGCGGTCGCGCGACGCTATCTGGA GGAGGGCGCGCGCTGCGTCCTCGTCGATCTGAAACCGGCCGACGGCGCGCTCGCGCGGCTCGTCGACGCGCATGCCGGCC GTGCGATCGCCGTGTCGGCGGACGTCACGCGCCGCGACGACATCGCGCGCATCGTCGCCACCGCCGTCGAGCGCTTCGGC GGCGTCGACATCCTGTTCAACAACGCGGCGCTCTTCGACATGCGCCCGCTCCTCGACGAATCGTGGGACGTGTTCGATCG CCTGTTCGCGGTCAACGTGAAGGGCCTGTTCTTCCTGATGCAGGCGGTCGCGCAGCGGATGGTCGAGCAGGGGCGCGGCG GCAAGATCGTCAACATGTCGTCGCAGGCGGGGCGCCGCGGCGAGGCGCTCGTGTCGCATTACTGCGCGACGAAGGCCGCG GTGCTGAGCTACACGCAGTCGGCCGCGCTCGCGCTCGCCAGGCACGGGATCAACGTGAACGGCATCGCGCCGGGCGTCGT CGACACGCCGATGTGGGAGCAGGTGGATGCGCTCTTCGCGCGCTACGAGAACCGGCCGCTCGGCGAGAAGAAGCGGCTCG TCGGCGAAGCGGTGCCGCTCGGCCGGATGGGCGTGCCCGACGATCTGACGGGCGCCGCGCTCTTTCTCGCCTCGGCGGAC GCCGATTACATCACCGCCCAGACGCTGAACGTCGACGGCGGCAACTGGATGAGCTGA
Upstream 100 bases:
>100_bases TGGCCGATCATTCGTTCGAAAATAGAGCAAATGATCGGCAAACGAGCGAACGCTCGCTTCGGCGGCCGGCGGCACGACAT ATAACGAATCGGAGACACCA
Downstream 100 bases:
>100_bases CATCATGGCCGCGATCGTCGCCGCGGGCGAGCTGCTCGCCGAATTCGTCGCCGCGAAGCGCGGCCAGGGCTTCGACGCGC CGGGCGAGTTCGCCGGCCCG
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSADVTRRDDIARIVATAVERFG GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGLFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VLSYTQSAALALARHGINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD ADYITAQTLNVDGGNWMS
Sequences:
>Translated_258_residues MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSADVTRRDDIARIVATAVERFG GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGLFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VLSYTQSAALALARHGINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD ADYITAQTLNVDGGNWMS >Mature_258_residues MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSADVTRRDDIARIVATAVERFG GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGLFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VLSYTQSAALALARHGINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD ADYITAQTLNVDGGNWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=34.5724907063197, Blast_Score=133, Evalue=2e-31, Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=35.2490421455939, Blast_Score=124, Evalue=8e-29, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30.3846153846154, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=34.2741935483871, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=30.6513409961686, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=31.1538461538462, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=32.1782178217822, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=33.0739299610895, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=29.6442687747036, Blast_Score=91, Evalue=2e-18, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=28.8973384030418, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI33667109, Length=252, Percent_Identity=31.7460317460317, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=34.4086021505376, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=30, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI4504505, Length=217, Percent_Identity=30.4147465437788, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=26.9430051813472, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=31.2138728323699, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=229, Percent_Identity=24.8908296943231, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=26.6968325791855, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=27.319587628866, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=34.375, Blast_Score=145, Evalue=3e-36, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=36.2595419847328, Blast_Score=134, Evalue=9e-33, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=34.2629482071713, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=32.6771653543307, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=31.7460317460317, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=32.5670498084291, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=35.632183908046, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=30.6513409961686, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=29.1666666666667, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=33.5907335907336, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=28.0155642023346, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=28.5140562248996, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=30.2197802197802, Blast_Score=77, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=33.59375, Blast_Score=135, Evalue=2e-32, Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=31.640625, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=32.5670498084291, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=29.5620437956204, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=33.203125, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=31.9548872180451, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=31.294964028777, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=30.0751879699248, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=32.4427480916031, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=29.2592592592593, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=29.368029739777, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=28.6764705882353, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=29.8039215686275, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=28.8888888888889, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=29.7794117647059, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=29.1512915129151, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=27.007299270073, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=31.5789473684211, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=28.5185185185185, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.5880149812734, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=30.3501945525292, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17564282, Length=210, Percent_Identity=30, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=27.037037037037, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=29.7794117647059, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=29.1828793774319, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=28.0612244897959, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=30.8755760368664, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=26.7676767676768, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=27.4611398963731, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=27.3764258555133, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=25.5102040816327, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=21.5686274509804, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=26.4248704663212, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=22.568093385214, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193207185, Length=155, Percent_Identity=27.741935483871, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=25, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=8e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=256, Percent_Identity=30.46875, Blast_Score=76, Evalue=5e-15, Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=26.0536398467433, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=35.1778656126482, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=33.4600760456274, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=34.251968503937, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=31.3953488372093, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=31.5175097276265, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=29.5719844357977, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=28.3582089552239, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI24644337, Length=207, Percent_Identity=30.9178743961353, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=26.4550264550265, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI281364892, Length=158, Percent_Identity=31.6455696202532, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=29.1828793774319, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=32.4742268041237, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=28.9340101522843, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=27.9187817258883, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665264, Length=201, Percent_Identity=26.3681592039801, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI221510726, Length=201, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24641232, Length=208, Percent_Identity=26.4423076923077, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 27630; Mature: 27630
Theoretical pI: Translated: 6.28; Mature: 6.28
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSA CCHHHHHHHEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEC DVTRRDDIARIVATAVERFGGVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGLFFLM CCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH QAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALARHGINVN HHHHHHHHHCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCC ADYITAQTLNVDGGNWMS CCEEEEEEEECCCCCCCC >Mature Secondary Structure MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSA CCHHHHHHHEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEC DVTRRDDIARIVATAVERFGGVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGLFFLM CCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH QAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALARHGINVN HHHHHHHHHCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCC ADYITAQTLNVDGGNWMS CCEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]