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The map label for this gene is mltB [H]

Identifier: 126453500

GI number: 126453500

Start: 2877972

End: 2879330

Strand: Direct

Name: mltB [H]

Synonym: BURPS1106A_2936

Alternate gene names: 126453500

Gene position: 2877972-2879330 (Clockwise)

Preceding gene: 126453339

Following gene: 126453177

Centisome position: 72.16

GC content: 66.52

Gene sequence:

>1359_bases
GTGTCGGTTATACTGCCCCGAAATCGTCCGTCTCGTCCGCTTCGCTTCGACATGATCTTCCACCAGCCTGCCGCACCCGC
CTCGCTCGCTTTCCGTCTTCGCTTCCCGCTCGCCGCGCTGTCGCTCGCCGCGACGCTCTTCGCGTCGGCCGCCGTCGCGC
AAACGCAGCCCGCCGCAGCCGTCGTCGCGCAAGAGCCGGCGCAATCGCAATCGCAATCGCAATCGCAATCGCAATCGCAA
TCGCAATCGCAGCCGCAGCCGCAGCCGCAGCCGCAGCCGAGCGTACAGCAGGGGCAAACATTCGAAGAAGAAATCATTCC
GCAGCGCTACGCGAACAACGCGAAGATCGACGCGTTCATCGCCGACATGGTCGCGCGCCACGACTTCGATGCGAACGCGC
TGCATGCGCTGTTCGCGCGCGTGAGCTACTCGGCGACCGCCGCGAAGCTCGTGATGCCCGCGCCGTCGCCAGCCGTCAAG
AACTGGCGCGTCTACCAGTCGCGCTTTCTCGACGCGGTGCGCGTGAACGCCGGCGTGAAATTCTGGCGCGCGAACCAAGG
CACGCTGCAACGCGCGTCCACGGAATTCGGCGTGCCGCCCGAGGTGATCGTCGGCATCATCGGCGTCGAGACGATCTACG
GCCGCTACATGGGCAACTTCCGCACGCTCGACGCGCTGACGACGCTCGCGTTCGACTATCCGAACACGCCGAATCGCGAC
GCGCGGCAGGCGACGTTCCGCAAGAATCTCGAAGATTTCCTCGTCTGGACGCGCGACAGCCAGCTCGACCCGACGGGCGT
GCTCGGCTCGTACACGGGCGCGGTCGGCATCCCGCAGTTCCTGCCGAGCAGCATCCGCGATTACGCGGTCGACTACGACG
GCAATGGTCACATCGATCTGCGCGCGAGCCAGGCCGATGCGATCGGCAGCGTCGCGAACTATCTGAAGCAGCACGGCTGG
GAAACCGGTCGGCCGGTAGTATGGAACATCGCGCCCGATACGGGCAGCCAGGGCGTCGCGCAAGCGGCGGCGGATGGTCG
CCCCGAGCCGCACTGGGTGCTGTCGCAGTTGCTGCGCGCGGGGCTCGTGCTCGACGAGCCGTCCGTGAACATCGCATCGG
AGGCGAGCACGCCCGCCACCGTGGTCGATTTGCCGACGCCCGGCCGCGCAACCGAATACAAGCTCGGACTGCAGAATTTC
TACGTGCTGACCCGCTACAACCGCAGCTTCTTCTATGCGCTCGCCGTCTATCAGCTGGGTGAGCGTGTGAAGGCGCAGAT
GGAAGCGAGCGGCGCGTTGACACCGTCGCCCGCCGACGCGGCAACCGGCTCACCCGCCGCACAGCCGCCGTCCGAATGA

Upstream 100 bases:

>100_bases
GCGCCGCAGGTCTCCGTCAAGGATGTCCGCGATATCGTCTGGTGCGAAGTTCGCCGCTAACTTACCACATCACGCCCCCC
GCCGGGCCGGCGCGACGGGC

Downstream 100 bases:

>100_bases
CGCCGACGCGGCGCGAAGCGAGCGATGGCTTGAACGAAGGCTGAATGAAAAGCGCCGCGTCAGCGGCGCTTCAGACTGCT
GACGAAACCCACGTTTTTCG

Product: lytic murein transglycosylase B

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSVILPRNRPSRPLRFDMIFHQPAAPASLAFRLRFPLAALSLAATLFASAAVAQTQPAAAVVAQEPAQSQSQSQSQSQSQ
SQSQPQPQPQPQPSVQQGQTFEEEIIPQRYANNAKIDAFIADMVARHDFDANALHALFARVSYSATAAKLVMPAPSPAVK
NWRVYQSRFLDAVRVNAGVKFWRANQGTLQRASTEFGVPPEVIVGIIGVETIYGRYMGNFRTLDALTTLAFDYPNTPNRD
ARQATFRKNLEDFLVWTRDSQLDPTGVLGSYTGAVGIPQFLPSSIRDYAVDYDGNGHIDLRASQADAIGSVANYLKQHGW
ETGRPVVWNIAPDTGSQGVAQAAADGRPEPHWVLSQLLRAGLVLDEPSVNIASEASTPATVVDLPTPGRATEYKLGLQNF
YVLTRYNRSFFYALAVYQLGERVKAQMEASGALTPSPADAATGSPAAQPPSE

Sequences:

>Translated_452_residues
MSVILPRNRPSRPLRFDMIFHQPAAPASLAFRLRFPLAALSLAATLFASAAVAQTQPAAAVVAQEPAQSQSQSQSQSQSQ
SQSQPQPQPQPQPSVQQGQTFEEEIIPQRYANNAKIDAFIADMVARHDFDANALHALFARVSYSATAAKLVMPAPSPAVK
NWRVYQSRFLDAVRVNAGVKFWRANQGTLQRASTEFGVPPEVIVGIIGVETIYGRYMGNFRTLDALTTLAFDYPNTPNRD
ARQATFRKNLEDFLVWTRDSQLDPTGVLGSYTGAVGIPQFLPSSIRDYAVDYDGNGHIDLRASQADAIGSVANYLKQHGW
ETGRPVVWNIAPDTGSQGVAQAAADGRPEPHWVLSQLLRAGLVLDEPSVNIASEASTPATVVDLPTPGRATEYKLGLQNF
YVLTRYNRSFFYALAVYQLGERVKAQMEASGALTPSPADAATGSPAAQPPSE
>Mature_451_residues
SVILPRNRPSRPLRFDMIFHQPAAPASLAFRLRFPLAALSLAATLFASAAVAQTQPAAAVVAQEPAQSQSQSQSQSQSQS
QSQPQPQPQPQPSVQQGQTFEEEIIPQRYANNAKIDAFIADMVARHDFDANALHALFARVSYSATAAKLVMPAPSPAVKN
WRVYQSRFLDAVRVNAGVKFWRANQGTLQRASTEFGVPPEVIVGIIGVETIYGRYMGNFRTLDALTTLAFDYPNTPNRDA
RQATFRKNLEDFLVWTRDSQLDPTGVLGSYTGAVGIPQFLPSSIRDYAVDYDGNGHIDLRASQADAIGSVANYLKQHGWE
TGRPVVWNIAPDTGSQGVAQAAADGRPEPHWVLSQLLRAGLVLDEPSVNIASEASTPATVVDLPTPGRATEYKLGLQNFY
VLTRYNRSFFYALAVYQLGERVKAQMEASGALTPSPADAATGSPAAQPPSE

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=325, Percent_Identity=41.2307692307692, Blast_Score=213, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 49055; Mature: 48924

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVILPRNRPSRPLRFDMIFHQPAAPASLAFRLRFPLAALSLAATLFASAAVAQTQPAAA
CCEECCCCCCCCCEEEEEEEECCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVAQEPAQSQSQSQSQSQSQSQSQPQPQPQPQPSVQQGQTFEEEIIPQRYANNAKIDAFI
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHH
ADMVARHDFDANALHALFARVSYSATAAKLVMPAPSPAVKNWRVYQSRFLDAVRVNAGVK
HHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCE
FWRANQGTLQRASTEFGVPPEVIVGIIGVETIYGRYMGNFRTLDALTTLAFDYPNTPNRD
EEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCH
ARQATFRKNLEDFLVWTRDSQLDPTGVLGSYTGAVGIPQFLPSSIRDYAVDYDGNGHIDL
HHHHHHHHCHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCEEEE
RASQADAIGSVANYLKQHGWETGRPVVWNIAPDTGSQGVAQAAADGRPEPHWVLSQLLRA
ECCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHC
GLVLDEPSVNIASEASTPATVVDLPTPGRATEYKLGLQNFYVLTRYNRSFFYALAVYQLG
CEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCEEEEEEEECCHHHHHHHHHHHH
ERVKAQMEASGALTPSPADAATGSPAAQPPSE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVILPRNRPSRPLRFDMIFHQPAAPASLAFRLRFPLAALSLAATLFASAAVAQTQPAAA
CEECCCCCCCCCEEEEEEEECCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVAQEPAQSQSQSQSQSQSQSQSQPQPQPQPQPSVQQGQTFEEEIIPQRYANNAKIDAFI
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHH
ADMVARHDFDANALHALFARVSYSATAAKLVMPAPSPAVKNWRVYQSRFLDAVRVNAGVK
HHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCE
FWRANQGTLQRASTEFGVPPEVIVGIIGVETIYGRYMGNFRTLDALTTLAFDYPNTPNRD
EEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCH
ARQATFRKNLEDFLVWTRDSQLDPTGVLGSYTGAVGIPQFLPSSIRDYAVDYDGNGHIDL
HHHHHHHHCHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCEEEE
RASQADAIGSVANYLKQHGWETGRPVVWNIAPDTGSQGVAQAAADGRPEPHWVLSQLLRA
ECCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHC
GLVLDEPSVNIASEASTPATVVDLPTPGRATEYKLGLQNFYVLTRYNRSFFYALAVYQLG
CEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCEEEEEEEECCHHHHHHHHHHHH
ERVKAQMEASGALTPSPADAATGSPAAQPPSE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]