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The map label for this gene is nrdD [C]

Identifier: 126453461

GI number: 126453461

Start: 2709335

End: 2711086

Strand: Direct

Name: nrdD [C]

Synonym: BURPS1106A_2742

Alternate gene names: 126453461

Gene position: 2709335-2711086 (Clockwise)

Preceding gene: 126454704

Following gene: 126452817

Centisome position: 67.93

GC content: 64.61

Gene sequence:

>1752_bases
ATGCACCCTTGCGCCGCGCCGAATCCCGCGTCGCGCGACAAGCCGTTGATCGACGTCGAATCGTCGATCAACGAATACCT
GGACCGGCAGGACTGGCGCGTCAACGCGAACGCGAACCAGGGCTATTCGCTCGGCGGCCTGATCCTGAACGTGTCCGGCA
AGGTGATCGCGAACTACTGGCTGAGCCACGTCTACCCGAGCGCGATCGGCGAAGCGCACCGCAATGCGGATCTGCACATC
CACGATCTCGACGTGCTGTCCGGCTACTGCGCGGGCTGGTCGCTGCGCACGCTGCTCAACGAAGGGTTGAACGGCGTGCC
CGGCAAGGTCGAGTCGGGGCCGCCGAAGCACATGTCGAGCGCGGTCGGCCAGATCGTGAACTTCCTCGGCACGCTGCAGA
ACGAATGGGCGGGCGCGCAGGCGTTCAGCTCGTTCGACACGTACATGGCGCCGTTCGTGCGCCGCGACGCGCTCACCTAC
GCCGAAGTGCGCCAGTCCGTCCAGGAACTGATCTACAACCTGAACGTGCCGTCACGCTGGGGCACGCAGACGCCGTTCAC
GAACCTGACGTTCGACTGGATCTGCCCCGAGGATCTGCGCGAGCAAGTGCCCGTGATCGCCGGCGAAGAGATGCCGTTCA
CGTACGGCGATCTGCAGCCCGAAATGGACATGATCAACCAGGCGTACATCGAGGTGATGCAGGCGGGCGACGCGGCGGGC
CGCGTGTTCACGTTCCCGATTCCGACCTACAACATCACCGCCGATTTCGACTGGCACAGCCCGAACGCCGAGCGCCTGTT
CGAGATGACCGCGCGCTACGGCCTGCCGTACTTCCAGAACTTCATCAATTCCGAGTTGAAGCCGAACATGATCCGCTCGA
TGTGCTGCCGGCTGCAGCTCGACCTGCGCGAGCTGATGAAGCGCGGCAACGGGCTGTTCGGCTCGGCCGAGCAGACGGGA
TCGATCGGCGTGGTCACCGTGAATTGCGCGCGGCTCGGCTATCTGCACGCGGGCGACGAGCGCGCGCTCTTCGCGCGGCT
CGACACGCTGCTCGACTACGGCAAGGAAAGCCTCGAGATCAAGCGCGAGGTGATCCAGCATCACATGAACAACGGGCTCT
TCCCGTACACGAAGCGCTATCTCGGCACGCTGCGCAATCATTTCTCGACGCTCGGCGTGAACGGCATCAACGAGATGATC
CGCAATTTCACGCGCGACGCGCACGATCTGACGACCGACTGGGGCCACGCGTTCGCGCTGCGCCTGCTCGACCACGTGCG
CGCGCGCATCGTCGAGTATCAGGAGGAAACGGGCCACATGTACAACCTCGAGGCGACGCCGGCCGAGGGCACGACGTACC
GCTTCGCGAAGGAAGACCGCCGCCGCTATCCGGACATCCTGCAGGCGGGCACGCCGCAGATGCCGTACTACACGAACTCG
TCGCAGTTGCCGGTAGGCTTCACCGACGATCCGTTCGAGGCGCTCGAACGCCAGGACGACCTGCAGCGCAAATACACGGG
CGGCACGGTGCTGCATCTGTACATGACCGAGCCGCTGTCGTCCGCCGACGCGTGCCGCACGCTCGTGAAGCGCGCGCTCA
CCCGCTTCTCGCTGCCGTATCTGACCGTCACGCCGACCTTCTCGATCTGCCCGACGCACGGCTATCTCGCCGGCAGCCAC
CCGTTTTGCCCGAAGTGCGACGAAGCGCTGCTGCGTCGCAAATTGTCTCAATCCCAACCGATGGAAGCCTGA

Upstream 100 bases:

>100_bases
CGCCGGATCGCCGTTGACCCATACAACATCTGGTATTTAGCATTCACCCCGTCACCAGATTTTGTGCCACCAACGAGAGA
GGCCCACGTTGTCCGAGACC

Downstream 100 bases:

>100_bases
ACATGACGACGACATTGCAAGCCAACCCACAAGCCGCCCGCGCCGCGATCGTGCTGTCCGACGACGAGCGCCAGCCGTGC
GAGATCTGGACCCGCGTGAT

Product: anaerobic ribonucleoside triphosphate reductase

Products: dUTP; H2O; Oxidized thioredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPSAIGEAHRNADLHI
HDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTY
AEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAGDAAG
RVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMKRGNGLFGSAEQTG
SIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMI
RNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPYYTNS
SQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTFSICPTHGYLAGSH
PFCPKCDEALLRRKLSQSQPMEA

Sequences:

>Translated_583_residues
MHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPSAIGEAHRNADLHI
HDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTY
AEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAGDAAG
RVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMKRGNGLFGSAEQTG
SIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMI
RNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPYYTNS
SQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTFSICPTHGYLAGSH
PFCPKCDEALLRRKLSQSQPMEA
>Mature_583_residues
MHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPSAIGEAHRNADLHI
HDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTY
AEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAGDAAG
RVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMKRGNGLFGSAEQTG
SIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMI
RNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPYYTNS
SQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTFSICPTHGYLAGSH
PFCPKCDEALLRRKLSQSQPMEA

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2 [C]

Molecular weight: Translated: 65872; Mature: 65872

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYW
CCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCCCEECCEEEECCCHHHHHHH
LSHVYPSAIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSS
HHHHCHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHH
AVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTYAEVRQSVQELIYNLNVPSRW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAGDAAG
CCCCCCCCCEEECCCCHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
RVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQL
CEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHH
DLRELMKRGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEI
HHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCHHHHHHHHHHHHCCHHHHHH
KREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMIRNFTRDAHDLTTDWGHAFAL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHCHHHHHHHH
RLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPYYTNS
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCHHHHHCCCCCCCEECCC
SQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPY
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCE
LTVTPTFSICPTHGYLAGSHPFCPKCDEALLRRKLSQSQPMEA
EEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHPCAAPNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYW
CCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCCCEECCEEEECCCHHHHHHH
LSHVYPSAIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLNEGLNGVPGKVESGPPKHMSS
HHHHCHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHH
AVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTYAEVRQSVQELIYNLNVPSRW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQAYIEVMQAGDAAG
CCCCCCCCCEEECCCCHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
RVFTFPIPTYNITADFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQL
CEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHH
DLRELMKRGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEI
HHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCHHHHHHHHHHHHCCHHHHHH
KREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMIRNFTRDAHDLTTDWGHAFAL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHCHHHHHHHH
RLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDILQAGTPQMPYYTNS
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCHHHHHCCCCCCCEECCC
SQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPY
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCE
LTVTPTFSICPTHGYLAGSHPFCPKCDEALLRRKLSQSQPMEA
EEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Reduced thioredoxin; UTP [C]

Specific reaction: Reduced thioredoxin + UTP --> dUTP + H2O + Oxidized thioredoxin [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]