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The map label for this gene is cbiG/cobJ [H]

Identifier: 126453452

GI number: 126453452

Start: 1930268

End: 1932097

Strand: Reverse

Name: cbiG/cobJ [H]

Synonym: BURPS1106A_1964

Alternate gene names: 126453452

Gene position: 1932097-1930268 (Counterclockwise)

Preceding gene: 126454586

Following gene: 126455294

Centisome position: 48.44

GC content: 76.5

Gene sequence:

>1830_bases
ATGACCGCCGCGCCCGCGATCGTGATACTCGGGCCGGGCGCGCTCGAGACCGCGCGCCGGATCCAGGCGCGCTTCGACGG
CGCGCGGGTGCACGCGCTCGCCGGGCGCGCCGAGGCGGACCTCGCGTTCGCCGAGCTCGGCCCGCATCTGCGCGAGCTGT
ATGCGCGCGGCGCGCCGATCGTCGCGCTGTTCGCGGCCGGCATCGCGATTCGCTGCGTCGCGCCGTGCCTCGCCGACAAG
GGCGCGGAGCCGCCCGTGCTCGCCGTCGCCGAGGACGGCAGCGCGGTCGTGCCGCTGTTGGGCGGCCTCGCGGGCGCCAA
CGCGCTCGCGCGCGAGATCGCCGACGCGCTCGGCGTCGCGGCCGCGATCACGACGAGCGGCGAACTGCGCTTCGGCGCGT
GCATGCTGAACCCGCCCGAAGGCTACGCGCTCGCCGATCTCGACGCGGGCAAGCGCTTCGTGTCCGATCTGCTCGCGGGC
GAAAGCACGCGCGTCGAAGGCGATGCGCGCTGGCTCGACGATGTCGCGCTGCCGCGCGACGCGCACGCGGCGCGCGTGAT
CCGCGTCACGCCGCATGCGTCGCGTGGCGACGCGCACGCGTTGCTGATCCATCCGCGCAGCGTCGTCGTCGCGTTGGGCG
ATGGCGATGGGGATAACGACGGCGAGGGCCTGCGCGACGACGCGCGCAGCGTCTCGGCGCCCGATGCCACCGGTCGCGCC
CGCGCGAACGCGGCGCCGGATCTGCCGCCGCTTGCCGCGCGCATCGCCGCCGCGCTCGCCGCGCATGATCTCGCGCCGCT
CGCGCTCGCGGCCGTCGTCGCGCCCGCGCGGCGCATCGCCGAGCACGCGCTGACCGACGCGGCGCGCGCGCTGCGCGCGC
CGTTGCGCTTCGTCGAAACGAACGCGCGCGACGCCGCCGGCGTGCTCGACGCCGCGTTGCCCGGGGCGCTCGCGCCGCGC
GTCGACGCCTCGCGCGCCGCGGCGGGCTCACCGCGAACGACGCCGCCCGAGCCGCGCGACGTCGCGATCGCCGTCGCCCG
CGCGCCCGTCGACGCCGATGCGCTCGGCATCGCGCGCGGCCGCCTGACGGTGCTCGGCCTCGGCCCCGGCCGCGCGGACC
TGATGACCCCCGCCGCGCGCGCGGCGCTCGCCGACGCGACCGACATCGTCGGCTACGCGACCTACGTGAACATGGCGGGC
CCGTTGCGCGCCGATCAGCAACTGCACGTATCCGACAACCGCGAGGAGCTGCAGCGCGCGCGCCACGCGTTCGAGCTCGC
CGCGCGGGGCCGGCGCGTCGCGGTCGTGTCCTCGGGCGACCCCGGCGTGTTCGCGATGGCGGCCGCCGTGCTCGAGGCGC
TCGACGGCGCCGACGACGCGCGCTGGGCGGCCGTCGAGCTCGACGTCGTGCCCGGCGTGTCGGCCGCGCTCGCGACGGCG
GCCGAAGCCGGCGCGCCGCTCGGCCACGATTTCTGCCTGATCTCGCTGTCGGACAACCTGAAGCCGTGGGCGATCATCGA
AAAACGCATCGATCACGCGGCGGCCGCCGATTTCGCGCTCGCGTTCTACAACCCGGTGTCGCGCGCGCGGCCCGTGCAGT
TCGATCGCGCGCTCGACATCGTGCGCCGGCATCGCGCGCCGGAGACGGTCGTCGTGCTCGGCCGCGACATCGGCCGCCCC
GGCGCGACGCTCGCGACGACGACGCTCGCCGCGCTGTCCGCGCAGCAGGTCGACATGCGCACGATGGTGATCGTCGGCTC
GTCGACGACGCGCCGCGTCGCGCGCGACGGCGCGCGCGACTGGGTGTATACGCCGCGCTGGTATCGCTGA

Upstream 100 bases:

>100_bases
CGACGATGGCCGCGCAGCGGATCGTGCCGCTCGCGGACGTCGATCCGATGGCGTCGCCGTATTTTTCGCTGCTCGTCGTG
CCGGGGGAAAAATGGCAAGG

Downstream 100 bases:

>100_bases
TATCGCGGCCGCCGAAGCGAGGCGACGCACGGCGCGTCGTCCCGCTTCGCCGGCAACGGGCGCGCCGCGCACCGAGCGCG
CCCGCTGCGCGCTTGCGCGC

Product: cobalamin biosynthesis protein CbiG/precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MTAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPIVALFAAGIAIRCVAPCLADK
GAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAG
ESTRVEGDARWLDDVALPRDAHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDNDGEGLRDDARSVSAPDATGRA
RANAAPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVETNARDAAGVLDAALPGALAPR
VDASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAG
PLRADQQLHVSDNREELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGVSAALATA
AEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDIVRRHRAPETVVVLGRDIGRP
GATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARDWVYTPRWYR

Sequences:

>Translated_609_residues
MTAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPIVALFAAGIAIRCVAPCLADK
GAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAG
ESTRVEGDARWLDDVALPRDAHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDNDGEGLRDDARSVSAPDATGRA
RANAAPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVETNARDAAGVLDAALPGALAPR
VDASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAG
PLRADQQLHVSDNREELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGVSAALATA
AEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDIVRRHRAPETVVVLGRDIGRP
GATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARDWVYTPRWYR
>Mature_608_residues
TAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPIVALFAAGIAIRCVAPCLADKG
AEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGE
STRVEGDARWLDDVALPRDAHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDNDGEGLRDDARSVSAPDATGRAR
ANAAPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVETNARDAAGVLDAALPGALAPRV
DASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGP
LRADQQLHVSDNREELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGVSAALATAA
EAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDIVRRHRAPETVVVLGRDIGRPG
ATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARDWVYTPRWYR

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 63022; Mature: 62891

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPI
CCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHCCCCH
VALFAAGIAIRCVAPCLADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGESTRVEGDARWLDDVALPRD
HEEECCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCCCCC
AHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDNDGEGLRDDARSVSAPDATGRA
CCCEEEEEECCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCC
RANAAPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVET
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NARDAAGVLDAALPGALAPRVDASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARG
CCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHEEECC
RLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQQLHVSDNREELQRA
CEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHH
RHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGVSAALATA
HHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
AEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDI
HHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHH
VRRHRAPETVVVLGRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARD
HHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCCC
WVYTPRWYR
CCCCCCCCC
>Mature Secondary Structure 
TAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPI
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHCCCCH
VALFAAGIAIRCVAPCLADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGESTRVEGDARWLDDVALPRD
HEEECCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCCCCC
AHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDNDGEGLRDDARSVSAPDATGRA
CCCEEEEEECCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCC
RANAAPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVET
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NARDAAGVLDAALPGALAPRVDASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARG
CCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHEEECC
RLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQQLHVSDNREELQRA
CEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHH
RHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGVSAALATA
HHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
AEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDI
HHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHH
VRRHRAPETVVVLGRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARD
HHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCCC
WVYTPRWYR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]