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The map label for this gene is moaE [H]

Identifier: 126453451

GI number: 126453451

Start: 2250616

End: 2251104

Strand: Reverse

Name: moaE [H]

Synonym: BURPS1106A_2265

Alternate gene names: 126453451

Gene position: 2251104-2250616 (Counterclockwise)

Preceding gene: 126452723

Following gene: 126452205

Centisome position: 56.44

GC content: 67.89

Gene sequence:

>489_bases
ATGGCGACGGTACGGGTGCAGGCGGACGATTTCGACGTGAGTGCCGAGATCGCGGCGCTGCGCGCGCGCAATCCGAAGGT
GGGCGCGATCGCGTGCTTCGTCGGCACGGTGCGCGATTTGAACGAAGGCGAGCAGGTCGACGCGCTCGAGCTCGAGCACT
ATCCGGGAATGACCGAGAAGGCGCTCGCCGCGATCGCGGAGGACGCGATCGCGCGCTGGCCGGGCATCGACGTCGCCATC
GTCCATCGGGTCGGCAAGCTGTATCCGCTTGATCAGATCGTGTTCGTCGCGACCGTGTCCGCGCACCGCGGCGACGCGTT
CCAGTCGTGCGAGTTCGTGATGGATTACCTGAAGACGCAGGCGCCGTTCTGGAAGAAGGAGAAGACGCCGGCGGGCGAGC
GCTGGGTCGACGCGCGCAGCGCCGACGACGCGGCGCTCGCGCGTTGGGGCGTCGAATCGGGGAACGCGCGGGAAAAGCGT
TCGACGTAG

Upstream 100 bases:

>100_bases
ATGGCGTGCAACCACACGATGACGGACGCCGGCACGCGGATCACCGAAGGCTGCGAGGTCGCGTTCTTCCCGCCCGTGAC
GGGCGGCTGAGGAGGCGACG

Downstream 100 bases:

>100_bases
GCGGGGTGGAACCCACCCGTTTCGCCCGAGTGAAAGGCGATGCCGGGCGATCGCGGGCTCGCCGGTCGCGGCGGGGCGTA
CCACGCGCGCTCCCTATTCG

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MATVRVQADDFDVSAEIAALRARNPKVGAIACFVGTVRDLNEGEQVDALELEHYPGMTEKALAAIAEDAIARWPGIDVAI
VHRVGKLYPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQAPFWKKEKTPAGERWVDARSADDAALARWGVESGNAREKR
ST

Sequences:

>Translated_162_residues
MATVRVQADDFDVSAEIAALRARNPKVGAIACFVGTVRDLNEGEQVDALELEHYPGMTEKALAAIAEDAIARWPGIDVAI
VHRVGKLYPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQAPFWKKEKTPAGERWVDARSADDAALARWGVESGNAREKR
ST
>Mature_161_residues
ATVRVQADDFDVSAEIAALRARNPKVGAIACFVGTVRDLNEGEQVDALELEHYPGMTEKALAAIAEDAIARWPGIDVAIV
HRVGKLYPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQAPFWKKEKTPAGERWVDARSADDAALARWGVESGNAREKRS
T

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=37.1681415929204, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1787003, Length=144, Percent_Identity=53.4722222222222, Blast_Score=161, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17509279, Length=111, Percent_Identity=36.036036036036, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356259, Length=128, Percent_Identity=36.71875, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17774; Mature: 17643

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVRVQADDFDVSAEIAALRARNPKVGAIACFVGTVRDLNEGEQVDALELEHYPGMTEK
CCEEEEECCCCCCHHHHHHHHCCCCCCEEHHEEHHHHHCCCCCCCCCEEECCCCCCCHHH
ALAAIAEDAIARWPGIDVAIVHRVGKLYPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQ
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHC
APFWKKEKTPAGERWVDARSADDAALARWGVESGNAREKRST
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ATVRVQADDFDVSAEIAALRARNPKVGAIACFVGTVRDLNEGEQVDALELEHYPGMTEK
CEEEEECCCCCCHHHHHHHHCCCCCCEEHHEEHHHHHCCCCCCCCCEEECCCCCCCHHH
ALAAIAEDAIARWPGIDVAIVHRVGKLYPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQ
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHC
APFWKKEKTPAGERWVDARSADDAALARWGVESGNAREKRST
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]