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The map label for this gene is rbsK [H]

Identifier: 126453421

GI number: 126453421

Start: 1824378

End: 1825352

Strand: Direct

Name: rbsK [H]

Synonym: BURPS1106A_1871

Alternate gene names: 126453421

Gene position: 1824378-1825352 (Clockwise)

Preceding gene: 126454096

Following gene: 126451531

Centisome position: 45.74

GC content: 77.64

Gene sequence:

>975_bases
ATGACGGCCGCCGTCGAACGCGCGGCCGGCGGGGCCTCGCCCGCGCGCGCCGGCAGGGTGATGGTGGTCGGCAGCCTGAA
CATGGACCTCGTCGTGCGCTCGGCGCGGCTGCCGCGGCCGGGCGAGACGCTCGCCGGCCGCTCGTTCGCGCAGGCGGCGG
GCGGCAAGGGCGGCAACCAGGCGGTCGCGGCCGCGCGGCTCGGCGCGCAGGTGGCGATGCTCGGCCGCGTCGGCGCGGAC
GCGCACGGCGCCGCGCTGCGCGCGGGGCTCGTCGCCGAGGGGATCGATTGCGTCGCGCTGTCGGTCAGCGCGACGGCGAC
GACGGGCGTCGCGCTCATCGTCGTCGACGATGCGAGCCAGAACGCGATCGTGATCGTCGCGGGCAGCAACGGCGAGGTGA
CCCCCGAATCGATCGCCGGGCACGAGGCGGCGATCGCCGCGGCCGACGTGCTGATCTGCCAGCTCGAGACGCCCGCCGCC
GCGGTTCGCGCGGCGCTGGCCGCCGGCCGCCGGCTCGGCAAGACCGTCGTGCTGAATCCGGCGCCCGCTGCCGGCCCGCT
GCCCGCCGACTGGTTGCCGCTCGTCGATTACCTGATCCCGAACGAAATCGAGGCCGCCGCGCTGACCGGCTTGCCGGTGC
GCGACCCGGCGAGCGCCGAGACCGCCGCGCGCGCGCTTGCGGCGGCTGGCGCGCGCAACGTGATCGTCACGCTGGGCGGC
CAGGGCGTTCTCGCGCTGACGGCGGACGGCGACGCGCGCCACTACCCGGCGCCGCGCGTCGCGGCCGTCGACACGACGGC
CGCGGGGGACACGTTCATCGGAGGTTTCGCCGCGCGGCTCGCCGCGCGCGACGCGCCGCACGACGCGATCCGGTTCGCGC
AGCGCGCGGCTGCGTTGTCGGTCACGCGCGCGGGCGCGCAGCCGTCGATTCCGACGCTCGCCGAGCTCGACGCGTTCGCG
CCGGGGCCGGCGTGA

Upstream 100 bases:

>100_bases
CGTCGGGCGCGCCGCAGCGCCGCCGCGTCGTGTCGCCGCGCCTCGTGCTGCGCGAGTCGACGACTGTCTACGTGGAGCCG
GCCGACGCCGGGTATCGCGG

Downstream 100 bases:

>100_bases
CACAACGCCGCGGTCGTGCCGGGCATGTAAGCCAAGAGAAAGAAAATATCGAGCCGGCGGCCGCGCCAAATAAGTTTTTC
TTCGCACGGGCGGCTGCCCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGAD
AHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAA
AVRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
QGVLALTADGDARHYPAPRVAAVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFA
PGPA

Sequences:

>Translated_324_residues
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGAD
AHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAA
AVRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
QGVLALTADGDARHYPAPRVAAVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFA
PGPA
>Mature_323_residues
TAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGADA
HGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAA
VRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGGQ
GVLALTADGDARHYPAPRVAAVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFAP
GPA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=40.7407407407407, Blast_Score=188, Evalue=6e-48,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=44.078947368421, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI87082343, Length=304, Percent_Identity=32.2368421052632, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081971, Length=283, Percent_Identity=26.8551236749117, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788484, Length=315, Percent_Identity=27.6190476190476, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788491, Length=298, Percent_Identity=24.8322147651007, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=40.9836065573771, Blast_Score=201, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=31.3432835820896, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=39.8671096345515, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24583886, Length=299, Percent_Identity=33.1103678929766, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31824; Mature: 31692

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQ
CCCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCHHCCCHHHHHHCCCCCCH
AVAAARLGAQVAMLGRVGADAHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQ
HHHHHHHCHHEEEHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCC
NAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAAVRAALAAGRRLGKTVVLNP
CEEEEEECCCCCCCHHHHCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECC
APAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
CCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QGVLALTADGDARHYPAPRVAAVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALS
CEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VTRAGAQPSIPTLAELDAFAPGPA
HEECCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQ
CCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCHHCCCHHHHHHCCCCCCH
AVAAARLGAQVAMLGRVGADAHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQ
HHHHHHHCHHEEEHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCC
NAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAAVRAALAAGRRLGKTVVLNP
CEEEEEECCCCCCCHHHHCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECC
APAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPASAETAARALAAAGARNVIVTLGG
CCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QGVLALTADGDARHYPAPRVAAVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALS
CEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VTRAGAQPSIPTLAELDAFAPGPA
HEECCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]