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The map label for this gene is czcR [H]

Identifier: 126453308

GI number: 126453308

Start: 3761285

End: 3762223

Strand: Reverse

Name: czcR [H]

Synonym: BURPS1106A_3859

Alternate gene names: 126453308

Gene position: 3762223-3761285 (Counterclockwise)

Preceding gene: 126455096

Following gene: 126451528

Centisome position: 94.33

GC content: 72.1

Gene sequence:

>939_bases
TTGAATACGCGTGATCTTCAAGCTTTCGTGGCGGTCGTCGACAGCGGCTCGATGGTGGCCGCCGCGACCCGGCTCCATCT
GACGCAGCCCGGCCTGACGCGGCGCGTGCAGAACCTCGAGACGACGCTCGGCGTGCCGCTCCTCGATCGGCAGAGCAAGC
CGCTCAAGCCGACCGCGGCGGGCCGCGAGGTCTACGCGCTCGCGCGCAACGTGCTGCGCTCGGTCGACGAACTGCTGGCC
GTCGCGGCGCCCGGTAGCGAGCCGGCGGGCGAACTGCGGATCGGCGTGCCGCCGTTTTTGTCGGAGCTCGCGCTCGAAGG
GCCGATCGACCGGCTACGCGACGCGTTTCCGCGCCTCACGCTGCGGATCACGGCCGGCTGGTCGCCGGCGCTGCTGGAAA
ACGTCGAGCGCGCAGTGCTCGATGCCGCCGCGGTGATGATGCCGGCAAGCTTCCCGATGCCGGAGACGCTCGTGTCGACG
CTGCTCGGCGTGCAGCCGACGGTGCTCGTCGCCGCGCGCGATTTCGCGCTGCCGCCGGGGCCGCTGTCGCTCGACGCGCT
GGCGCGCTATCCGTGGGTGCTGAGCCAGGACGGCTGCGGGATGCGCTCCGCGCTGAGCCGCGCGTTCAGCGCGGCGGGGC
TGCCGTTCGACGTCGCGGTCGAAGCATTCGGCTCGGATCTGCAGCTCTCGCTCGTCGCGCGCGGCGCGGGGCTCGGCATC
GCATCGGCGTCCGCGCTCGCGCGCAGCCCGCACCGGAATGCGCTGCGGATCGTCGAAACGGCGGATGTCGAGCCGGGAAT
CAACGTATGGCTCGTGCACGGCGTGCTGCCGGGCCGGCTGATGCGGCCCGTCGAGCTGCTGCGCGAGCGGCTCGCCGCGG
TGCTGGAGGAGGAAAGAAGCCGGCGGTTGGGCGGCGAAGCGGACATGCCGGCCAATTAG

Upstream 100 bases:

>100_bases
TTCATCGAAAGGATCTCGGGAAACGAACGAGCTCCTATCGTAGAGATGCGCTTGTTATGCGACAATTGAAATATGTTCAA
TATGATTATGCGAGTTTGTT

Downstream 100 bases:

>100_bases
AGCCGGCATTCAAGGGAAAATCCGTATTTTCTACAAGGAAATGTTGCATTGCGTCAAACAAACCGGTATAGTTTGAACCG
TCTCCTCCATGTCTCCTCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAAGREVYALARNVLRSVDELLA
VAAPGSEPAGELRIGVPPFLSELALEGPIDRLRDAFPRLTLRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVST
LLGVQPTVLVAARDFALPPGPLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
ASASALARSPHRNALRIVETADVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERSRRLGGEADMPAN

Sequences:

>Translated_312_residues
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAAGREVYALARNVLRSVDELLA
VAAPGSEPAGELRIGVPPFLSELALEGPIDRLRDAFPRLTLRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVST
LLGVQPTVLVAARDFALPPGPLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
ASASALARSPHRNALRIVETADVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERSRRLGGEADMPAN
>Mature_312_residues
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAAGREVYALARNVLRSVDELLA
VAAPGSEPAGELRIGVPPFLSELALEGPIDRLRDAFPRLTLRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVST
LLGVQPTVLVAARDFALPPGPLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
ASASALARSPHRNALRIVETADVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERSRRLGGEADMPAN

Specific function: Transcriptional Activator For The Hut, Put And Ure Operons And Repressor For The Gdh And Gltb Operons In Response To Nitrogen Limitation. Negative Regulator Of Its Own Expression (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=30.2788844621514, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=28.8, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790399, Length=315, Percent_Identity=27.3015873015873, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788481, Length=243, Percent_Identity=28.3950617283951, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789506, Length=221, Percent_Identity=24.8868778280543, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787806, Length=273, Percent_Identity=24.1758241758242, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787879, Length=276, Percent_Identity=27.8985507246377, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI145693105, Length=264, Percent_Identity=26.8939393939394, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789440, Length=196, Percent_Identity=27.5510204081633, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=239, Percent_Identity=27.6150627615063, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789639, Length=189, Percent_Identity=27.5132275132275, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788296, Length=272, Percent_Identity=24.6323529411765, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33171; Mature: 33171

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAA
CCCHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GREVYALARNVLRSVDELLAVAAPGSEPAGELRIGVPPFLSELALEGPIDRLRDAFPRLT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHCCCHHHHHHHCCCEE
LRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVSTLLGVQPTVLVAARDFALPPG
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
PLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
CCCHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCH
ASASALARSPHRNALRIVETADVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERS
HHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RRLGGEADMPAN
HHCCCCCCCCCC
>Mature Secondary Structure
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAA
CCCHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GREVYALARNVLRSVDELLAVAAPGSEPAGELRIGVPPFLSELALEGPIDRLRDAFPRLT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHCCCHHHHHHHCCCEE
LRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVSTLLGVQPTVLVAARDFALPPG
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
PLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
CCCHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCH
ASASALARSPHRNALRIVETADVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERS
HHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RRLGGEADMPAN
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA