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The map label for this gene is acdA [H]

Identifier: 126453242

GI number: 126453242

Start: 1287440

End: 1288636

Strand: Direct

Name: acdA [H]

Synonym: BURPS1106A_1316

Alternate gene names: 126453242

Gene position: 1287440-1288636 (Clockwise)

Preceding gene: 126453643

Following gene: 126452328

Centisome position: 32.28

GC content: 66.58

Gene sequence:

>1197_bases
ATGGATCTCGATTATTCCCCCGCCGACGACGCGTTCCGCGCCGAAATCCGCGCGTGGCTCGAGGCGAATCTGCCTCGCGC
GCTGCGCGACAAGGTGCTCAACCACAAACGTCTGAATCGCGACGATTTCGCGGGCTGGCACCGGCTGCTCGGCACGCGAG
GCTGGTCCGCGCCCGCATGGCCCGCCGAATACGGCGGGCCCGGCTGGAACGCGACGCAGCGCCATATCTGGGAAGAGGAA
TGCGCGCGCATCGGCGCGCCGCCCGTGCTGCCGTTCGGCGTGTCGATGGTCGCGCCGGTGCTGATGAAGTACGGCAGCGA
AGCGCAGAAGCGCCGCTATCTGCCGCGCATCCTGGACGGCACCGACTGGTGGTGCCAGGGCTACTCGGAGCCCGGCTCGG
GTTCGGATCTCGCGTCGCTGCGCACGCGCGCCGAGCGCCGCGGCGATCATTACCTCGTCAACGGCCAGAAGACCTGGACG
ACGCTCGGCCAGCACGCGGACATGATGTTCTGCCTCGTGCGCACCGATCCCGACGCGAAGAAGCAGGAAGGGATCTCGTT
CCTGCTGATCGACATGAAATCGCCCGGCATCACGGTGCGCCCGATCGTCACGCTCGACGAGGATCGCGAAGTCAACGAGG
TGTTCTTCGAGGATGTGAAGGTGCCCGTCGAGAATCTCGTCGGCGACGAGAATCGCGGCTGGACCTACGCGAAATATCTG
CTCGGGCACGAGCGCACCGGCATCGCCCGGGTCGGCGCGTCGAAGCGCGAACTCGATTTCCTGAAGCGCATCGCGTCACG
CGAGCGCAAGAACGGCAAGCCGCTCATCGCCGATCCCGTGTTCGCCGCGAAGATCGCCGCGCTGGAGATCGAGTTGATGG
CGCTCGAGGTCACGGTGCTGCGCGTCGTCAGCAGCGAGGCGAGCGGGCGCGGGCCGGGGCCGGAGGCGTCGATGCTGAAG
ATCAAGGGCACCGAGATCCAGCAGGCGCTGACCGAACTGATGGTCGACGCGATCGGGCCGCTCGCCGCGCCGTTCGACGC
CGCGTTCCTCGAAGGCGAGCGCGAGCGCAGCATCGCCGGCGACGACGACGCGGCGCCGCTCGCCGCGTATTACTTCAACT
ACCGCAAGACGTCGATCTATGGCGGTTCGAACGAAATCCAGAAGAACATCATCGCGCAGATGATTCTCGGCCTGTGA

Upstream 100 bases:

>100_bases
GCTGCCGGTTCCCGCCGCGCTGAAAGAGCCTTTGCAGTGATCGCCCGCTGATCGCTGCGCGGCCCGCGGGCGGCCGGCGC
GGTCAGAGGAGACACTGCGC

Downstream 100 bases:

>100_bases
GGAGCGGCGCCATGAACTTCACTTTCAGCGAAGAACAACAGCAATTCGCCCATGCGCTGCGCCGCTATCTCGACGAGCGC
TACGGCTTCGACGCGCGGCG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDLDYSPADDAFRAEIRAWLEANLPRALRDKVLNHKRLNRDDFAGWHRLLGTRGWSAPAWPAEYGGPGWNATQRHIWEEE
CARIGAPPVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDGTDWWCQGYSEPGSGSDLASLRTRAERRGDHYLVNGQKTWT
TLGQHADMMFCLVRTDPDAKKQEGISFLLIDMKSPGITVRPIVTLDEDREVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGASKRELDFLKRIASRERKNGKPLIADPVFAAKIAALEIELMALEVTVLRVVSSEASGRGPGPEASMLK
IKGTEIQQALTELMVDAIGPLAAPFDAAFLEGERERSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL

Sequences:

>Translated_398_residues
MDLDYSPADDAFRAEIRAWLEANLPRALRDKVLNHKRLNRDDFAGWHRLLGTRGWSAPAWPAEYGGPGWNATQRHIWEEE
CARIGAPPVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDGTDWWCQGYSEPGSGSDLASLRTRAERRGDHYLVNGQKTWT
TLGQHADMMFCLVRTDPDAKKQEGISFLLIDMKSPGITVRPIVTLDEDREVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGASKRELDFLKRIASRERKNGKPLIADPVFAAKIAALEIELMALEVTVLRVVSSEASGRGPGPEASMLK
IKGTEIQQALTELMVDAIGPLAAPFDAAFLEGERERSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
>Mature_398_residues
MDLDYSPADDAFRAEIRAWLEANLPRALRDKVLNHKRLNRDDFAGWHRLLGTRGWSAPAWPAEYGGPGWNATQRHIWEEE
CARIGAPPVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDGTDWWCQGYSEPGSGSDLASLRTRAERRGDHYLVNGQKTWT
TLGQHADMMFCLVRTDPDAKKQEGISFLLIDMKSPGITVRPIVTLDEDREVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGASKRELDFLKRIASRERKNGKPLIADPVFAAKIAALEIELMALEVTVLRVVSSEASGRGPGPEASMLK
IKGTEIQQALTELMVDAIGPLAAPFDAAFLEGERERSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=408, Percent_Identity=26.2254901960784, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI226958414, Length=308, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226958412, Length=346, Percent_Identity=26.878612716763, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4501859, Length=340, Percent_Identity=27.3529411764706, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI4557233, Length=359, Percent_Identity=27.0194986072423, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI4557231, Length=301, Percent_Identity=27.5747508305648, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI187960098, Length=301, Percent_Identity=27.5747508305648, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI211971008, Length=351, Percent_Identity=26.7806267806268, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI48976061, Length=351, Percent_Identity=26.7806267806268, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI21361497, Length=298, Percent_Identity=28.5234899328859, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI7656849, Length=214, Percent_Identity=28.0373831775701, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4557235, Length=199, Percent_Identity=32.6633165829146, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI76496475, Length=199, Percent_Identity=32.6633165829146, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38505218, Length=310, Percent_Identity=25.4838709677419, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4503943, Length=292, Percent_Identity=26.3698630136986, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI7669494, Length=292, Percent_Identity=26.3698630136986, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87081958, Length=401, Percent_Identity=23.1920199501247, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786223, Length=406, Percent_Identity=21.4285714285714, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=341, Percent_Identity=26.3929618768328, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=383, Percent_Identity=26.1096605744125, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=346, Percent_Identity=27.1676300578035, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=356, Percent_Identity=27.5280898876405, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17570075, Length=421, Percent_Identity=24.9406175771971, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=264, Percent_Identity=31.4393939393939, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=226, Percent_Identity=33.6283185840708, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17551932, Length=212, Percent_Identity=31.1320754716981, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=197, Percent_Identity=32.48730964467, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=226, Percent_Identity=33.6283185840708, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=210, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=271, Percent_Identity=25.0922509225092, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=257, Percent_Identity=27.2373540856031, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=194, Percent_Identity=26.2886597938144, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=265, Percent_Identity=25.2830188679245, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562446, Length=350, Percent_Identity=24.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=390, Percent_Identity=26.9230769230769, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355753, Length=313, Percent_Identity=28.7539936102236, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24666513, Length=346, Percent_Identity=26.3005780346821, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI281363737, Length=282, Percent_Identity=29.0780141843972, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24660351, Length=183, Percent_Identity=33.879781420765, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646207, Length=359, Percent_Identity=26.7409470752089, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920834, Length=400, Percent_Identity=24, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44374; Mature: 44374

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDYSPADDAFRAEIRAWLEANLPRALRDKVLNHKRLNRDDFAGWHRLLGTRGWSAPAW
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC
PAEYGGPGWNATQRHIWEEECARIGAPPVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDG
CHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCHHHHCC
TDWWCQGYSEPGSGSDLASLRTRAERRGDHYLVNGQKTWTTLGQHADMMFCLVRTDPDAK
CCHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCEEEEEEECCCCCH
KQEGISFLLIDMKSPGITVRPIVTLDEDREVNEVFFEDVKVPVENLVGDENRGWTYAKYL
HHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHH
LGHERTGIARVGASKRELDFLKRIASRERKNGKPLIADPVFAAKIAALEIELMALEVTVL
HCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHEEEHHHHHHHHH
RVVSSEASGRGPGPEASMLKIKGTEIQQALTELMVDAIGPLAAPFDAAFLEGERERSIAG
HHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCCCC
DDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
CCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLDYSPADDAFRAEIRAWLEANLPRALRDKVLNHKRLNRDDFAGWHRLLGTRGWSAPAW
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC
PAEYGGPGWNATQRHIWEEECARIGAPPVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDG
CHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCHHHHCC
TDWWCQGYSEPGSGSDLASLRTRAERRGDHYLVNGQKTWTTLGQHADMMFCLVRTDPDAK
CCHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCEEEEEEECCCCCH
KQEGISFLLIDMKSPGITVRPIVTLDEDREVNEVFFEDVKVPVENLVGDENRGWTYAKYL
HHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHH
LGHERTGIARVGASKRELDFLKRIASRERKNGKPLIADPVFAAKIAALEIELMALEVTVL
HCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHEEEHHHHHHHHH
RVVSSEASGRGPGPEASMLKIKGTEIQQALTELMVDAIGPLAAPFDAAFLEGERERSIAG
HHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCCCC
DDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
CCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]