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The map label for this gene is cidA [H]

Identifier: 126452971

GI number: 126452971

Start: 26127

End: 26597

Strand: Direct

Name: cidA [H]

Synonym: BURPS1106A_0025

Alternate gene names: 126452971

Gene position: 26127-26597 (Clockwise)

Preceding gene: 126455044

Following gene: 126454133

Centisome position: 0.66

GC content: 75.8

Gene sequence:

>471_bases
ATGAGCAGGATTTCGGCTACGGCGGCAACCGCGACTCGCCCGACGACGGCGGCGCCCGCGCGCGTGGGCCGCGCGGCGCG
CGTCGCGTTGCAGACGGCCGCGCTCGGCGCGCTGTGGGCGGCGATCGACTGGACGGTGCGCGCGTTCGGCGTGCCGGTGC
CGTCCGGCGTGGTCGGCCTCGCGGTGCTGCTCGCGCTGCTGCTGTCCGGCCGCGTCGCGCCCGGCTGGGTGAAGGACGGC
GCGAACTGGCTGCTGTCCGACATGCTGCTCTTCTTCATCCCGGCGACCGTCGCGGCCGTGCAGTACGGCGGCCTCTTCAA
GGCGGACGGCTGGCGGCTCGCGCTCGTCGTCGTCGCCGGAACCACGTTCGTGATGCTGTCGGTGGCGATCGCGGTCGACG
TCGCGGCGGGCTTCGAGCGGCGGCTCGCGGTGATGCGCGTGCGTGCCGGCCGCCGCCGCGCGCGGGCCTGA

Upstream 100 bases:

>100_bases
TAAACGGAATGGGTTTTATAGAACCAAGTCATTTTATTTATGGACGCGTGAATCCTATACTGCCTCCATTCTGTAAAGCA
AGGCATTTCGGGAGCATTCG

Downstream 100 bases:

>100_bases
CGTGGCACGGTTTCCCCTTTCCCCATTTCATGCCATTCGTTGATGGCACCGGTTCCGAAGGCCGCATCATGACGACGCCC
GATCTCTCGTTTCTCACCGC

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSRISATAATATRPTTAAPARVGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDG
ANWLLSDMLLFFIPATVAAVQYGGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA

Sequences:

>Translated_156_residues
MSRISATAATATRPTTAAPARVGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDG
ANWLLSDMLLFFIPATVAAVQYGGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA
>Mature_155_residues
SRISATAATATRPTTAAPARVGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDGA
NWLLSDMLLFFIPATVAAVQYGGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 16253; Mature: 16122

Theoretical pI: Translated: 12.50; Mature: 12.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRISATAATATRPTTAAPARVGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGL
CCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AVLLALLLSGRVAPGWVKDGANWLLSDMLLFFIPATVAAVQYGGLFKADGWRLALVVVAG
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHH
TTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRISATAATATRPTTAAPARVGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGL
CCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AVLLALLLSGRVAPGWVKDGANWLLSDMLLFFIPATVAAVQYGGLFKADGWRLALVVVAG
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHH
TTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA