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The map label for this gene is lrp [H]

Identifier: 126452877

GI number: 126452877

Start: 3743960

End: 3744475

Strand: Reverse

Name: lrp [H]

Synonym: BURPS1106A_3844

Alternate gene names: 126452877

Gene position: 3744475-3743960 (Counterclockwise)

Preceding gene: 126452222

Following gene: 126454674

Centisome position: 93.88

GC content: 65.31

Gene sequence:

>516_bases
ATGGCGCACGTGGAATTGGATGCGATTGACCGGCGCATTCTTTCTATCCTTCAGGAGAATGGGCGTTTGTCGAACCAGGA
CATCGCCGAGCGGGTGAATCTGTCGCCGAGTCCTTGCCTGAGGCGGATCCGCCGGCTCGAGGAAATGGGCGTGATCACCG
GCTACGTCGCGCTGCTCGATCCGCAGAAGCTCGGGCTCGATCTGCTCGCGTACGTGAGCGTGCGGCTGGAGAAGCGCGGC
GGCGTCGCGCCCGTGCGCGGCGACGAGACGTCCGCGCGCGCCGGCGCGACCCATGCCGAGCTGTTCCGCGCGGCGGTGCA
GGCGTGGCCGGAAGTGGTCGCGTGCCACGCGATGACGGGCGACATGGATTATCTGCTGCGCGTGCAGGTCGAGGACATGG
CGCATTTCTCGCGCTTCATGCAGGAGCAACTGCTGCACCATCCGTCGGTGATCGACGTGAAGACGAGTTTCTCGCTCGAG
CGCTTCAAGGAAACGACCGCGCTGCCGATCCGCTGA

Upstream 100 bases:

>100_bases
AAGTGTAGCGGGGAGAGCCGAGTGGAAACTTGCGAACTTGGTCGCGCAACGCTACGCTTGCGCAATTTCTCGTCCGCACG
AACAGGCAGGGAGACAGGAA

Downstream 100 bases:

>100_bases
ACAGCATACATACGGTGCGCGGCCGGCCGGGCGGCCGCACGACGTGCGCCGCGGCCGGCTCAAAAAAACGGGCGGCCCGT
TGTGGACCGCCCGTTCCCGT

Product: putative leucine-responsive regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALLDPQKLGLDLLAYVSVRLEKRG
GVAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRFMQEQLLHHPSVIDVKTSFSLE
RFKETTALPIR

Sequences:

>Translated_171_residues
MAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALLDPQKLGLDLLAYVSVRLEKRG
GVAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRFMQEQLLHHPSVIDVKTSFSLE
RFKETTALPIR
>Mature_170_residues
AHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALLDPQKLGLDLLAYVSVRLEKRGG
VAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTGDMDYLLRVQVEDMAHFSRFMQEQLLHHPSVIDVKTSFSLER
FKETTALPIR

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=167, Percent_Identity=40.7185628742515, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI87081742, Length=165, Percent_Identity=40, Blast_Score=127, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 19231; Mature: 19100

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALLD
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PQKLGLDLLAYVSVRLEKRGGVAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DMDYLLRVQVEDMAHFSRFMQEQLLHHPSVIDVKTSFSLERFKETTALPIR
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AHVELDAIDRRILSILQENGRLSNQDIAERVNLSPSPCLRRIRRLEEMGVITGYVALLD
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PQKLGLDLLAYVSVRLEKRGGVAPVRGDETSARAGATHAELFRAAVQAWPEVVACHAMTG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DMDYLLRVQVEDMAHFSRFMQEQLLHHPSVIDVKTSFSLERFKETTALPIR
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]