Click here to switch to the map view.

The map label for this gene is clpX [H]

Identifier: 126452859

GI number: 126452859

Start: 2336047

End: 2337318

Strand: Reverse

Name: clpX [H]

Synonym: BURPS1106A_2364

Alternate gene names: 126452859

Gene position: 2337318-2336047 (Counterclockwise)

Preceding gene: 126451473

Following gene: 126453756

Centisome position: 58.6

GC content: 61.64

Gene sequence:

>1272_bases
ATGGCGGACAAGAAAGGTTCGAACAGCGAGAAGCTGTTGTATTGCTCGTTTTGCGGCAAAAGCCAGCATGAGGTGAAGAA
GCTCATCGCGGGGCCGTCGGTATTCATCTGCGATGAATGTATCGACTTGTGCAACGAGATCATCCGCGACGAAGCGGCCG
CGGCGGGCGTCGAAGCCAGCCTGTCCAAATCCGACCTGCCGAGCCCGCAGGAGATTCGCGACATCCTCGATCAGTACGTG
ATCGGCCAGGAGCGCGCGAAGAAGATCCTCGCCGTCGCCGTCTACAATCACTACAAGCGCCTGAAGCATCTCGACAAGAA
GGACGATGTCGAGTTGTCGAAGAGCAACATCCTGTTGATCGGCCCGACGGGCTCCGGCAAGACGCTGCTCGCGCAGACCC
TCGCGCGCCTGCTGAACGTGCCGTTCGTGATCGCCGACGCGACCACGCTGACGGAGGCCGGTTATGTCGGCGAGGACGTC
GAGAACATCATCCAGAAGCTGCTGCAGAACTGCAACTACGAGGTCGAGAAGGCGCAGCGCGGGATCGTCTACATCGACGA
AATCGACAAGATCAGCCGCAAGTCGGACAACCCGTCGATCACCCGCGACGTGTCGGGCGAGGGCGTCCAGCAGGCGCTGC
TCAAGCTCGTCGAGGGCACGATGGCGTCGGTGCCGCCGCAGGGCGGCCGCAAGCACCCGAACCAGGATTTCATCCAGGTC
GACACCACCAACATCCTGTTCATTTGCGGCGGCGCGTTCGACGGCCTCGAGAAGGTGATCACCGACCGCACCGAAAAGAC
CGGCATCGGTTTCGGCGCGACGGTCAAGAGCAAGCAGGAGCGGGACGCGGGCGAAGTGCTGCGCGAGGTCGAGCCGGAAG
ACCTGATCAAATTCGGGTTGATCCCCGAGCTGATCGGCCGTCTGCCGGTGGTCGCGACGCTCGGCAAGCTCGATGAAGCC
GCGCTGATGAAGATTCTCGTCGAGCCGAAGAACGCGCTCGTCAAGCAGTATCAGAAGCTGTTCGCGATGGAGCGGGTCGA
ACTCGAGATTCGTCCGGACGCGCTGCAAGCCGTCGCCCGCAAGGCGATCCGCCGCAAGACGGGCGCGCGCGGGCTGCGTT
CGATCATCGAGCAGGCGCTCCTCGACGTGATGTACGAACTGCCGACGCTCAAGGGCGTCAGCAAGGTGATCATCGACGAC
AATGTCATCGAAGGAGACGGCAAGCCGTTATTGATCTATGAGGACACGCCGAAAGTGGCGGGTTCGAATTGA

Upstream 100 bases:

>100_bases
GCAAAAGAACATCGCCGCCGTCTCCCGAGTATTTACCAGGTCATGGTGTCGGGGACAAACGGCGTATTATGTAACTCATG
TGTCCGGAGGCTCTACATTC

Downstream 100 bases:

>100_bases
CCGGCTTTGACGTTTCGTGAGGAAAAAAGCCGTTCATGGAATCGTGAGCGGCTTTTTTTCGTTTATCTTGTGGGTAACTC
TGACTCGCACCGTACGGTGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSKSDLPSPQEIRDILDQYV
IGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDEA
ALMKILVEPKNALVKQYQKLFAMERVELEIRPDALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTLKGVSKVIIDD
NVIEGDGKPLLIYEDTPKVAGSN

Sequences:

>Translated_423_residues
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSKSDLPSPQEIRDILDQYV
IGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDEA
ALMKILVEPKNALVKQYQKLFAMERVELEIRPDALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTLKGVSKVIIDD
NVIEGDGKPLLIYEDTPKVAGSN
>Mature_422_residues
ADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSKSDLPSPQEIRDILDQYVI
GQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVE
NIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVD
TTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDEAA
LMKILVEPKNALVKQYQKLFAMERVELEIRPDALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTLKGVSKVIIDDN
VIEGDGKPLLIYEDTPKVAGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=333, Percent_Identity=52.8528528528528, Blast_Score=325, Evalue=7e-89,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=73.7349397590361, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=46, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988663, Length=389, Percent_Identity=42.9305912596401, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI71982908, Length=297, Percent_Identity=47.4747474747475, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=297, Percent_Identity=47.4747474747475, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=44.1767068273092, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6319704, Length=447, Percent_Identity=38.7024608501119, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=46.6049382716049, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=46.6049382716049, Blast_Score=290, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46420; Mature: 46289

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEAS
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHH
LSKSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLI
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQR
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLREVEPEDLIKFGL
ECCEEEEEECCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCHHHHHHHCCHHHHHHHCC
IPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYQKLFAMERVELEIRPDALQAVAR
HHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHHH
KAIRRKTGARGLRSIIEQALLDVMYELPTLKGVSKVIIDDNVIEGDGKPLLIYEDTPKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCCEEECCCCEEEEECCCCCCC
GSN
CCC
>Mature Secondary Structure 
ADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEAS
CCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHH
LSKSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLI
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQR
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLREVEPEDLIKFGL
ECCEEEEEECCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCHHHHHHHCCHHHHHHHCC
IPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYQKLFAMERVELEIRPDALQAVAR
HHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHHH
KAIRRKTGARGLRSIIEQALLDVMYELPTLKGVSKVIIDDNVIEGDGKPLLIYEDTPKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCCEEECCCCEEEEECCCCCCC
GSN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA