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The map label for this gene is ftsK [H]

Identifier: 126452613

GI number: 126452613

Start: 2971968

End: 2974274

Strand: Reverse

Name: ftsK [H]

Synonym: BURPS1106A_3043

Alternate gene names: 126452613

Gene position: 2974274-2971968 (Counterclockwise)

Preceding gene: 126453486

Following gene: 126452390

Centisome position: 74.57

GC content: 67.84

Gene sequence:

>2307_bases
ATGGCAAAAGCACCTTATACCGCTCAGGCCCAGGCGCTACCGCACCGGATGTCGCGCCTACTGACCGAGATCCGCTGGAT
TCTCCAGGTCGCGCTGCTCGCCTTCCTGCTGATGGCGCTCCTGAGCTACAGCCGGCGCGATCCGAGCTGGACCCACGCCG
CGCAGGTCGACCACATCGCGAACTGGGCAGGGCGGGTCGGCGCATGGACGGCCGACATCATGCTGCTGCTCTTCGGCCTG
TCCGCGTACTGGCTCATCGTGCTGCTCGGCCGGCGCGTGGCCGCGAACTATCGTCGCATCACCCGGCACGACGCGCTGCC
CGGCGAGCCGGAGAAGCCGGCCGGCTGGCTCGCCGAAGGCTTCGCGTTCGTGCTCGTGCTGCTCGCGAGTGACGGCATCG
AGGCGCTGCGGATGTGGTCGCTGAAAGTGCAGTTGCCGCGCGCGCCGGGCGGCGTCGTCGGCGAGACGGTCGCGCGCGGC
GTCGCGCACGCGCTCGGCTTCACTGGCGGCACGCTCGCGCTGCTGATCGCGCTCGCGATCGGGCTGTCGCTGTATTTCCG
CTTTTCGTGGCTGTCGGTCGCCGAACGCGTCGGCGACGCGATCATCAACGCGTTCACGCTCGCGAAGCTGCGCCGCGAGG
CCGAGCGCGACCGCAAGCTCGGCGAGGCCGCGGCCGTCAAGCGCGAGGGCAAGGTGGAGGAGGAGCGCGTGCGCATCGAG
GAGCACGAGCCCGTCACGATCGTGCCGCCCGTCGTCACGCCCGCCAAATCCGAGCGCGCCGAGAAGGAGCGCCAGCAGCC
GCTGTTCACCGATCTGCCGGGCGATTCGACGCTGCCCGCGATCGCGCTGCTCGACCCCGCGCCGACGTCGCAGGAGACGA
TCTCCGCGGACACGCTCGAATTCACCTCGCGCCTGATCGAGAAGAAGCTGAAGGATTTCGGCGTCGAGGTGAGCGTCGTC
GCCGCGTATCCGGGCCCCGTCGTCACCCGCTACGAGATCGAGCCGGCGACGGGCGTGAAGGGCAGCCAGATCGTCAATCT
GTCGAAGGATCTCGCGCGCTCGCTGTCGCTCGTGTCGATCCGCGTCGTCGAGACGATTCCCGGCAAGAACTTCATGGCGC
TCGAATTGCCGAACCAGCGCCGCCAGACGGTGCGGCTGTCCGAGATCCTCGGCTCCGAGGTCTATGCGGACGCGCCGTCG
ATGCTCACCCTCGGCCTCGGCAAGGACATCGGCGGCAAGCCGGTGTGCGCGGATCTCGCGAAGATGCCGCACTTGCTCGT
CGCCGGCACGACGGGCTCGGGCAAGTCGGTGGGGATCAACGCGATGATCCTGTCGCTGCTCTACAAGGCGAGCGCCGAGC
AGGTGCGCCTCATCCTGATCGATCCGAAGATGCTCGAAATGAGCGTCTACGAAGGCATTCCGCATCTGCTGTGCCCGGTC
GTCACCGACATGCGCCAGGCAGGCCACGCGCTGAACTGGACCGTCGCCGAGATGGAGCGCCGCTACAAGCTGATGAGCAA
GCTCGGCGTGCGCAATCTCGCCGGCTACAACAACAAGATCGAGGACGCGAAGAAGCGCGAAGAGAAGATCCCGAATCCGT
TCAGCCTGACGCCGGACGATCCGGAGCCGCTCGGCCGGCTGCCGAACATCGTCGTCGTGATCGACGAGCTGGCCGATCTG
ATGATGGTCGTCGGCAAGAAGGTGGAGGAGCTGATCGCGCGGATCGCGCAGAAGGCGCGCGCCGCGGGCATCCACCTGAT
TCTCGCGACGCAGCGCCCGTCGGTCGACGTGATCACGGGCCTCATCAAGGCCAACGTGCCGACGCGGATCGCGTTCCAGG
TGTCGTCGAAGATCGATTCGCGCACGATTCTCGACCAGATGGGCGCCGAATCGCTGCTCGGCCAGGGCGATATGCTGTAC
CTGCCGCCCGGCAGCGGGCTGCCCGTGCGCGTGCACGGCGCGTTCGTGTCGGACGACGAAGTGCACCGCGTCGTCGAGAA
GCTCAAGGAGCACGGCGAGCCGAACTACATCGAGGGCCTCCTCGAGGGCGGCACGATCGACGGCGACGAAGGCTCGGCCG
CGGGAACGGGCGAAGCGAACGGCGAGTCCGACCCGTTGTACGACCAGGCGGTCGAGATCGTCATCAAGAACCGGCGCGCG
TCGATCTCGCTCGTGCAGCGCCACCTGCGCATCGGCTACAACCGCGCGGCGCGGCTGCTCGAGCAAATGGAGCAGTCGGG
GCTCGTGTCGGCGATGTCGTCGAGCGGGAACCGCGAAATCCTCACCCCCGCGCGCGACGCGGAGTGA

Upstream 100 bases:

>100_bases
CGGCGGCGCAGCGTTTACAATAGATCGGATCGAACGATCGGCGGGCTGTCGGCGGTTTCTTGCCGCACGCGGCCGCCTCA
TCGCCCCTTTTGACGGATTC

Downstream 100 bases:

>100_bases
ATCCGCGCCGGCGCGCCTGCCGAACGCGCGCCGGCCCTCTACGGAGAAAACCACAGCATGCAGCATCAGTCGTTGGCAGT
TCATACCGGCTCCGGCTCCG

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 767

Protein sequence:

>768_residues
MAKAPYTAQAQALPHRMSRLLTEIRWILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRVGAWTADIMLLLFGL
SAYWLIVLLGRRVAANYRRITRHDALPGEPEKPAGWLAEGFAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARG
VAHALGFTGGTLALLIALAIGLSLYFRFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIE
EHEPVTIVPPVVTPAKSERAEKERQQPLFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLIEKKLKDFGVEVSVV
AAYPGPVVTRYEIEPATGVKGSQIVNLSKDLARSLSLVSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPS
MLTLGLGKDIGGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPV
VTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGRLPNIVVVIDELADL
MMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLY
LPPGSGLPVRVHGAFVSDDEVHRVVEKLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRA
SISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILTPARDAE

Sequences:

>Translated_768_residues
MAKAPYTAQAQALPHRMSRLLTEIRWILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRVGAWTADIMLLLFGL
SAYWLIVLLGRRVAANYRRITRHDALPGEPEKPAGWLAEGFAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARG
VAHALGFTGGTLALLIALAIGLSLYFRFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIE
EHEPVTIVPPVVTPAKSERAEKERQQPLFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLIEKKLKDFGVEVSVV
AAYPGPVVTRYEIEPATGVKGSQIVNLSKDLARSLSLVSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPS
MLTLGLGKDIGGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPV
VTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGRLPNIVVVIDELADL
MMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLY
LPPGSGLPVRVHGAFVSDDEVHRVVEKLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRA
SISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILTPARDAE
>Mature_767_residues
AKAPYTAQAQALPHRMSRLLTEIRWILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIANWAGRVGAWTADIMLLLFGLS
AYWLIVLLGRRVAANYRRITRHDALPGEPEKPAGWLAEGFAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARGV
AHALGFTGGTLALLIALAIGLSLYFRFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIEE
HEPVTIVPPVVTPAKSERAEKERQQPLFTDLPGDSTLPAIALLDPAPTSQETISADTLEFTSRLIEKKLKDFGVEVSVVA
AYPGPVVTRYEIEPATGVKGSQIVNLSKDLARSLSLVSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPSM
LTLGLGKDIGGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPVV
TDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDDPEPLGRLPNIVVVIDELADLM
MVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYL
PPGSGLPVRVHGAFVSDDEVHRVVEKLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRAS
ISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILTPARDAE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=493, Percent_Identity=63.4888438133874, Blast_Score=608, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 83689; Mature: 83558

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPYTAQAQALPHRMSRLLTEIRWILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
NWAGRVGAWTADIMLLLFGLSAYWLIVLLGRRVAANYRRITRHDALPGEPEKPAGWLAEG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARGVAHALGFTGGTLALLIALAI
HHHHHHHHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GLSLYFRFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
EHEPVTIVPPVVTPAKSERAEKERQQPLFTDLPGDSTLPAIALLDPAPTSQETISADTLE
CCCCEEEECCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCCCCHHHHHHHHH
FTSRLIEKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVNLSKDLARSLSLVSI
HHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHEE
RVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPSMLTLGLGKDIGGKPVCADLA
EEEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCCCCCHHHHHH
KMPHLLVAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPV
HCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
VTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
PEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITG
CHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
LIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYLPPGSGLPVRVHGAFVSDDE
HHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEEEEEECCCHH
VHRVVEKLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRA
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
SISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILTPARDAE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure 
AKAPYTAQAQALPHRMSRLLTEIRWILQVALLAFLLMALLSYSRRDPSWTHAAQVDHIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
NWAGRVGAWTADIMLLLFGLSAYWLIVLLGRRVAANYRRITRHDALPGEPEKPAGWLAEG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGETVARGVAHALGFTGGTLALLIALAI
HHHHHHHHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GLSLYFRFSWLSVAERVGDAIINAFTLAKLRREAERDRKLGEAAAVKREGKVEEERVRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
EHEPVTIVPPVVTPAKSERAEKERQQPLFTDLPGDSTLPAIALLDPAPTSQETISADTLE
CCCCEEEECCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCCCCHHHHHHHHH
FTSRLIEKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVNLSKDLARSLSLVSI
HHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHEE
RVVETIPGKNFMALELPNQRRQTVRLSEILGSEVYADAPSMLTLGLGKDIGGKPVCADLA
EEEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCCCCCHHHHHH
KMPHLLVAGTTGSGKSVGINAMILSLLYKASAEQVRLILIDPKMLEMSVYEGIPHLLCPV
HCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
VTDMRQAGHALNWTVAEMERRYKLMSKLGVRNLAGYNNKIEDAKKREEKIPNPFSLTPDD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
PEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITG
CHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
LIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGQGDMLYLPPGSGLPVRVHGAFVSDDE
HHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEEEEEECCCHH
VHRVVEKLKEHGEPNYIEGLLEGGTIDGDEGSAAGTGEANGESDPLYDQAVEIVIKNRRA
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
SISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILTPARDAE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]