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The map label for this gene is degQ [H]

Identifier: 126452486

GI number: 126452486

Start: 3626366

End: 3627574

Strand: Direct

Name: degQ [H]

Synonym: BURPS1106A_3709

Alternate gene names: 126452486

Gene position: 3626366-3627574 (Clockwise)

Preceding gene: 126453444

Following gene: 226830779

Centisome position: 90.92

GC content: 66.58

Gene sequence:

>1209_bases
ATGCTTAGACGCTTCTGGCTGTTCTTCGCCCAAGCGGTGACGGTGCTGCTCGCACTGATGTTCATCGTGGCGACGCTCAA
GCCGCAATGGCTCCAACGGCAAGGCCAGCTCGGCAAGCAGCTCGCGGCGCCGATCGTCGCGCTGCGGGAAGTCGCGCCCG
GCGTCGGCGGCGCGCCCGCTCAATCCTCGTATGCGGACGCCGCGCAAAAGGCGATGCCCGCGGTCGTCAACGTGTTCTCC
AGCAAGGACGGTTCGCTGCCGCCCGATCCGCGCGCGAAGGATCCGCTGTTTCGCTATTTCTTCGGCGACCGCAACGCGCG
CCGGCAGCAGGAGGAACCCGCGGCCAATCTGGGGTCGGGCGTCATCGTAAGCTCGGAGGGTTACATTCTAACGAACCAGC
ACGTCGTCGACGGCGCGGACCAGATCGAAGTCGCGCTCGCCGACGGCCGCACGGCCACCGCGAAGGTGATCGGCAGCGAT
CCGGAAACCGACCTCGCGGTGCTCAAGATCAACATGACGAACCTGCCGACGATCACGCTCGGCCGCTCCGACCAGTCGCG
CGTGGGCGACGTCGTGCTCGCGATCGGCAACCCGTTCGGGGTCGGCCAGACGGTCACGATGGGGATCATCAGCGCGCTCG
GGCGCAACCACCTCGGCATCAACACGTTCGAGAACTTCATCCAGACCGACGCGCCGATCAACCCGGGCAATTCGGGCGGC
GCGCTCGTCGACGTAAACGGCAACCTGCTCGGCATCAATACGGCGATCTACTCGCGCTCGGGCGGCTCGCTCGGCATCGG
CTTCGCGATCCCCGTGTCGACCGCGCGCAACGTGCTCGAGAGCATCATCACGACGGGCACCGTCACGCGCGGCTGGATCG
GCGTCGAGCCGCAGGACGTGACGCCGGAGATCGCCGAATCGTTCAGCCTTGCGCAAAAATCGGGCGCGATCGTTGCGGGC
GTGCTGCAAGGCGGCCCGGCCGACAAGGCAGGCATCAAGCCGGGCGATATTCTGATGTCGATCGACGGCGAGGACATCAC
CGATACGACGAAGCTGCTGAACGTCGTCGCGCAGATCAAGCCCGGCACGCCGGCGAAGGTTCACGTGGTGCGCAAGGGCA
AGGAGCTCGACGTCACCGTCGTGATCGGCAAGCGGCCGCCGCCGCCGAAGCAGGCGCTCGACGACCAGAACAGCGACGAG
GAGGAGTGA

Upstream 100 bases:

>100_bases
GGCCGTTCGGGCTGTAGTCCTTGAACCGCCCGATTTCGAGGGTATTGTTCAAGTACAATTCAAGTTCGATCCGATCCATA
TAAACCTCTAGTATCTTCAA

Downstream 100 bases:

>100_bases
GCGGCGGCGCGCCCCGCGCACGCGCGCGAGGCACGCGCTAGACGGCCGGCGACACGGCCGCGGGGCAGCCCGCCGATGCC
GCCTGCCCGGCCGGCGACTT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MLRRFWLFFAQAVTVLLALMFIVATLKPQWLQRQGQLGKQLAAPIVALREVAPGVGGAPAQSSYADAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARRQQEEPAANLGSGVIVSSEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARNVLESIITTGTVTRGWIGVEPQDVTPEIAESFSLAQKSGAIVAG
VLQGGPADKAGIKPGDILMSIDGEDITDTTKLLNVVAQIKPGTPAKVHVVRKGKELDVTVVIGKRPPPPKQALDDQNSDE
EE

Sequences:

>Translated_402_residues
MLRRFWLFFAQAVTVLLALMFIVATLKPQWLQRQGQLGKQLAAPIVALREVAPGVGGAPAQSSYADAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARRQQEEPAANLGSGVIVSSEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARNVLESIITTGTVTRGWIGVEPQDVTPEIAESFSLAQKSGAIVAG
VLQGGPADKAGIKPGDILMSIDGEDITDTTKLLNVVAQIKPGTPAKVHVVRKGKELDVTVVIGKRPPPPKQALDDQNSDE
EE
>Mature_402_residues
MLRRFWLFFAQAVTVLLALMFIVATLKPQWLQRQGQLGKQLAAPIVALREVAPGVGGAPAQSSYADAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARRQQEEPAANLGSGVIVSSEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARNVLESIITTGTVTRGWIGVEPQDVTPEIAESFSLAQKSGAIVAG
VLQGGPADKAGIKPGDILMSIDGEDITDTTKLLNVVAQIKPGTPAKVHVVRKGKELDVTVVIGKRPPPPKQALDDQNSDE
EE

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=361, Percent_Identity=32.9639889196676, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7019477, Length=289, Percent_Identity=35.6401384083045, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=34.6456692913386, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI22129776, Length=317, Percent_Identity=32.807570977918, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1789629, Length=326, Percent_Identity=45.398773006135, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1786356, Length=343, Percent_Identity=42.2740524781341, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789630, Length=329, Percent_Identity=43.161094224924, Blast_Score=228, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24646839, Length=307, Percent_Identity=33.8762214983713, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 42224; Mature: 42224

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFWLFFAQAVTVLLALMFIVATLKPQWLQRQGQLGKQLAAPIVALREVAPGVGGAPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QSSYADAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDRNARRQQEEPAANLGSG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHCCHHHCCCC
VIVSSEGYILTNQHVVDGADQIEVALADGRTATAKVIGSDPETDLAVLKINMTNLPTITL
EEEECCCEEEECCEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCEEEE
GRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARNVLESIITTGTVTRGWIGVEPQDV
EEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCC
TPEIAESFSLAQKSGAIVAGVLQGGPADKAGIKPGDILMSIDGEDITDTTKLLNVVAQIK
CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PGTPAKVHVVRKGKELDVTVVIGKRPPPPKQALDDQNSDEEE
CCCCCEEEEEECCCEEEEEEEECCCCCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MLRRFWLFFAQAVTVLLALMFIVATLKPQWLQRQGQLGKQLAAPIVALREVAPGVGGAPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QSSYADAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDRNARRQQEEPAANLGSG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHCCHHHCCCC
VIVSSEGYILTNQHVVDGADQIEVALADGRTATAKVIGSDPETDLAVLKINMTNLPTITL
EEEECCCEEEECCEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCEEEE
GRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARNVLESIITTGTVTRGWIGVEPQDV
EEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCC
TPEIAESFSLAQKSGAIVAGVLQGGPADKAGIKPGDILMSIDGEDITDTTKLLNVVAQIK
CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PGTPAKVHVVRKGKELDVTVVIGKRPPPPKQALDDQNSDEEE
CCCCCEEEEEECCCEEEEEEEECCCCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]