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The map label for this gene is qor [H]

Identifier: 126452470

GI number: 126452470

Start: 1222592

End: 1223566

Strand: Direct

Name: qor [H]

Synonym: BURPS1106A_1245

Alternate gene names: 126452470

Gene position: 1222592-1223566 (Clockwise)

Preceding gene: 126453334

Following gene: 126453780

Centisome position: 30.65

GC content: 69.03

Gene sequence:

>975_bases
ATGCCGAAGGCAATTCGTTACGACCAGCCGGGCGGCCCGGAAGTCATGAAATGGGTCGACATCGACGTCGGCGCGCCGCA
GCCGGGCGAAGTCCGCATCAAGCAGCACGCGGTCGGCCTGAACTACATCGACGTCTATTTCCGCACCGGCCTGTATCCGC
AACCGCTGCCGGGCGGTCTCGGCATGGAGGCGGCGGGCGAGGTCACGGAGCTCGGCGAAGGCGTGACGGCGCTCAAGCCG
GGCGACCGCGTCGCGTATGTCGCGCAGCCGCCGGGCGCATACGCGCAGGAGCGCGTGCTGGCCGCCGCGAAGCTCGTGAA
GCTGCCGGAGGCCATCGGCTACGAGGACGCGGCGTCGGCGATGCTGCAGGGCCTGACCGCGCAATATCTGCTGCGTCGCA
CGTACAAGGTCGAGCCGGGCGACACGATCGTCATTCACGCGGCGGCGGGCGGCGTGGGCCTGCTCGTCTGCCAGTGGGCG
AAGGCGCTCGGCGCGACGGTGATCGGCACGGTCGGCTCCGACGAGAAGGCCGCGCTCGCGAAGGCGCACGGCTGCGATCA
CCCGATCGTCTACACGCGCGAGAACTTCACCGAACGCGTGAAGGAGATCACGAACGGCGCGGGCGTGCCGGTGGTCTACG
ATTCGATCGGCAAGGACACGTACATCGGCTCGCTCGACTGTCTCGCGCCGCTCGGCATGTTCGTGAGCTTCGGCAACGCG
TCCGGGCCGCTGCCGCCGATCGACTCGAAGGAGTTCTCGTCGCGCGGCTCGCTGTTCTTCACGCGGCCGACGTTGTTCTC
GTACATCGCCAAGCGCGAGGATCTCGATCGCAACGCGGCCGAGCTGTTCGACGTGCTCGCGTCCGGCCGCGTGAAGACGA
GCATCCGGCAGCGCTATCCGCTCGAGAACGTCGCGCAGGCGCACCGCGACCTCGAGGCGCGGCGCACCACGGGCTCGACG
GTCCTGCTGCCCTGA

Upstream 100 bases:

>100_bases
CGGGCGCAGCGCTCGTCCACGCATGGCGCGCGCCCGCGCATCACCCGAGGGCGCGGGCCGATTCCGAACTCAACGCACAT
CGCAACCAGGAGAAGCCAGC

Downstream 100 bases:

>100_bases
GCCTCATGCGGCCGCGGGCGCGCCGCGGCCGGGCCCGCGCGCGCATCGCGCGCCGCGTGCCGGCTCGTTCGCCGGCCGCG
CGCGAACGAGCCAGCGCCGC

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPKAIRYDQPGGPEVMKWVDIDVGAPQPGEVRIKQHAVGLNYIDVYFRTGLYPQPLPGGLGMEAAGEVTELGEGVTALKP
GDRVAYVAQPPGAYAQERVLAAAKLVKLPEAIGYEDAASAMLQGLTAQYLLRRTYKVEPGDTIVIHAAAGGVGLLVCQWA
KALGATVIGTVGSDEKAALAKAHGCDHPIVYTRENFTERVKEITNGAGVPVVYDSIGKDTYIGSLDCLAPLGMFVSFGNA
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKREDLDRNAAELFDVLASGRVKTSIRQRYPLENVAQAHRDLEARRTTGST
VLLP

Sequences:

>Translated_324_residues
MPKAIRYDQPGGPEVMKWVDIDVGAPQPGEVRIKQHAVGLNYIDVYFRTGLYPQPLPGGLGMEAAGEVTELGEGVTALKP
GDRVAYVAQPPGAYAQERVLAAAKLVKLPEAIGYEDAASAMLQGLTAQYLLRRTYKVEPGDTIVIHAAAGGVGLLVCQWA
KALGATVIGTVGSDEKAALAKAHGCDHPIVYTRENFTERVKEITNGAGVPVVYDSIGKDTYIGSLDCLAPLGMFVSFGNA
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKREDLDRNAAELFDVLASGRVKTSIRQRYPLENVAQAHRDLEARRTTGST
VLLP
>Mature_323_residues
PKAIRYDQPGGPEVMKWVDIDVGAPQPGEVRIKQHAVGLNYIDVYFRTGLYPQPLPGGLGMEAAGEVTELGEGVTALKPG
DRVAYVAQPPGAYAQERVLAAAKLVKLPEAIGYEDAASAMLQGLTAQYLLRRTYKVEPGDTIVIHAAAGGVGLLVCQWAK
ALGATVIGTVGSDEKAALAKAHGCDHPIVYTRENFTERVKEITNGAGVPVVYDSIGKDTYIGSLDCLAPLGMFVSFGNAS
GPLPPIDSKEFSSRGSLFFTRPTLFSYIAKREDLDRNAAELFDVLASGRVKTSIRQRYPLENVAQAHRDLEARRTTGSTV
LLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=31.7220543806647, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=31.7220543806647, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=29.7124600638978, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=29.7872340425532, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI28557745, Length=226, Percent_Identity=33.1858407079646, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI24308257, Length=323, Percent_Identity=27.2445820433437, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI197927207, Length=192, Percent_Identity=30.2083333333333, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI67078404, Length=173, Percent_Identity=31.7919075144509, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI41872631, Length=239, Percent_Identity=30.5439330543933, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI47519420, Length=334, Percent_Identity=26.9461077844311, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI67078406, Length=122, Percent_Identity=34.4262295081967, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=47.7064220183486, Blast_Score=311, Evalue=5e-86,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=26.8518518518519, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=303, Percent_Identity=26.4026402640264, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17556000, Length=274, Percent_Identity=27.007299270073, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=38.5802469135802, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI45550423, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330659, Length=211, Percent_Identity=29.8578199052133, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19920632, Length=211, Percent_Identity=29.8578199052133, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34729; Mature: 34598

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAIRYDQPGGPEVMKWVDIDVGAPQPGEVRIKQHAVGLNYIDVYFRTGLYPQPLPGGL
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHCCCCCEEEHHHCCCCCCCCCCCC
GMEAAGEVTELGEGVTALKPGDRVAYVAQPPGAYAQERVLAAAKLVKLPEAIGYEDAASA
CCCCCCCHHHHCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
MLQGLTAQYLLRRTYKVEPGDTIVIHAAAGGVGLLVCQWAKALGATVIGTVGSDEKAALA
HHHHHHHHHHHHHHEECCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHH
KAHGCDHPIVYTRENFTERVKEITNGAGVPVVYDSIGKDTYIGSLDCLAPLGMFVSFGNA
HHCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKREDLDRNAAELFDVLASGRVKTSIRQRYP
CCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCC
LENVAQAHRDLEARRTTGSTVLLP
HHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
PKAIRYDQPGGPEVMKWVDIDVGAPQPGEVRIKQHAVGLNYIDVYFRTGLYPQPLPGGL
CCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHCCCCCEEEHHHCCCCCCCCCCCC
GMEAAGEVTELGEGVTALKPGDRVAYVAQPPGAYAQERVLAAAKLVKLPEAIGYEDAASA
CCCCCCCHHHHCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
MLQGLTAQYLLRRTYKVEPGDTIVIHAAAGGVGLLVCQWAKALGATVIGTVGSDEKAALA
HHHHHHHHHHHHHHEECCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHH
KAHGCDHPIVYTRENFTERVKEITNGAGVPVVYDSIGKDTYIGSLDCLAPLGMFVSFGNA
HHCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKREDLDRNAAELFDVLASGRVKTSIRQRYP
CCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCC
LENVAQAHRDLEARRTTGSTVLLP
HHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]